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High-Performance Liquid Chromatography (HPLC) is a key technique in the evaluation of biopharmaceuticals. To improve the separation of biopharmaceuticals, it is crucial to improve the fundamental understanding of the parameters governing their band b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaed2a0423a969562fbc2c6d6eb58912
https://hdl.handle.net/20.500.14017/03fa0c0a-8d05-46af-a2ff-d2c395003d6a
https://hdl.handle.net/20.500.14017/03fa0c0a-8d05-46af-a2ff-d2c395003d6a
Autor:
Donatela Sadriaj, Deirdre Cabooter, Devin Makey, Dwight R. Stoll, Monika Dittmann, Gert Desmet, Huiying Song
Publikováno v:
Journal of chromatography. A. 1637
In an ongoing effort to better understand the underlying mechanisms of band broadening in particle-packed reversed-phase liquid chromatography columns, new models for intra-particle diffusion, representing an adsorption- and partition-type retention
Publikováno v:
Journal of Chromatography A. 1532:124-135
The accuracy of the longitudinal diffusion term (b-term) plays a vital role in the study of mass transfer mechanisms in high performance liquid chromatography (HPLC). In this study, three commonly used methodologies (peak parking; fitting of an exper