Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Donata Maciaczyk"'
Autor:
Julia Tsiampali, Silke Neumann, Beatriz Giesen, Katharina Koch, Donata Maciaczyk, Christoph Janiak, Daniel Hänggi, Jaroslaw Maciaczyk
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 378 (2020)
Glioblastoma (GBM) is the most aggressive malignant primary brain tumour in adulthood. Despite strong research efforts current treatment options have a limited impact on glioma stem-like cells (GSCs) which contribute to GBM formation, progression and
Externí odkaz:
https://doaj.org/article/0a002d75bddb4b26929821b23563c844
Autor:
Philippe Aretz, Donata Maciaczyk, Suad Yusuf, Rüdiger V. Sorg, Daniel Hänggi, Hongjia Liu, Hongde Liu, Tikam Chand Dakal, Amit Sharma, Ramakrishna Bethanabatla, Silke Neumann, Jarek Maciaczyk
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4562
Isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GBM) is a fast growing and highly heterogeneous tumor, often characterized by the presence of glioblastoma stem cells (GSCs). The plasticity of GSCs results in therapy resistance and impairs anti-
Autor:
Daniel Hänggi, Christoph Janiak, Donata Maciaczyk, Silke Neumann, Katharina Koch, Beatriz Giesen, Julia Tsiampali, Jaroslaw Maciaczyk
Publikováno v:
Pharmaceuticals, Vol 13, Iss 378, p 378 (2020)
Pharmaceuticals
Volume 13
Issue 11
Pharmaceuticals
Volume 13
Issue 11
Glioblastoma (GBM) is the most aggressive malignant primary brain tumour in adulthood. Despite strong research efforts current treatment options have a limited impact on glioma stem-like cells (GSCs) which contribute to GBM formation, progression and
Autor:
Julia Tsiampali, Silke Neumann, Donata Maciaczyk, Jaroslaw Maciaczyk, Sara J. Fraser-Miller, Keith C. Gordon, Sarah L. Young, Chima Robert
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 252:119534
Raman spectroscopy (RS) has been used as a powerful diagnostic and non-invasive tool in cancer diagnosis as well as in discrimination of cancer and immune cells. In this study RS in combination with chemometrics was applied to cellular Raman spectral
Autor:
Katharina Koch, Friederike Schröter, Jaroslaw Maciaczyk, Rudolf Hartmann, Ulf Dietrich Kahlert, Donata Maciaczyk, Dieter Willbold, Abigail K. Suwala, Andrea Caroline Krüger
Publikováno v:
OncoTarget 7(45), 73414-73431 (2016). doi:10.18632/oncotarget.12337
Oncotarget
Oncotarget
// Katharina Koch 1 , Rudolf Hartmann 2 , Friederike Schroter 3 , Abigail Kora Suwala 1 , Donata Maciaczyk 1 , Andrea Caroline Kruger 1 , Dieter Willbold 2, 4 , Ulf Dietrich Kahlert 1, 5 , Jaroslaw Maciaczyk 1 1 Neurosurgery Department, University Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a068c7f9695515e88462b4d6f33f1a1
https://hdl.handle.net/2128/12542
https://hdl.handle.net/2128/12542
Autor:
Gabriele Niedermann, Jaroslaw Maciaczyk, Marco Prinz, Tomasz Bogiel, Soroush Doostkam, Charles G. Eberhart, Ulf Dietrich Kahlert, Donata Maciaczyk, Brent A. Orr, Jörg Schubert, Guido Nikkhah, Thomas Brabletz, Brian W. Simons, Thomas Reithmeier
Publikováno v:
Cancer Letters. 325:42-53
Here we show that activation of the canonical WNT/β-catenin pathway increases the expression of stem cell genes and promotes the migratory and invasive capacity of glioblastoma. Modulation of WNT signaling alters the expression of epithelial-to-mese
Autor:
Jaroslaw Maciaczyk, Guido Nikkhah, Josef Bischofberger, Donata Maciaczyk, C.E. Jannes, Guilherme Lepski
Publikováno v:
Molecular and cellular neurosciences
Introduction Differentiation of neuronal progenitor cells (NPCs) in vitro into functional neurons is dependent on a complex cascade of molecular signaling pathways, many of which remain unknown. More specifically, in human NPCs the relationship betwe
Publikováno v:
Experimental Neurology. 213:354-362
Freshly isolated fetal midbrain neural precursor cells (NPCs) that maintain the potential to differentiate into dopamine (DA) neurons represent a valuable source for cell therapy in Parkinson's disease. However, it is poorly understood why midbrain N
Autor:
Johanna Wessolleck, Ulf Dietrich Kahlert, Mischa Schmidt, Jens Osterholz, Martin O. Steinhauser, Jaroslaw Maciaczyk, Donata Maciaczyk, Guido Nikkhah, Benjamin Merkt
Publikováno v:
Scientific Reports
The impact of pressure waves on cells may provide several possible applications in biology and medicine including the direct killing of tumors, drug delivery or gene transfection. In this study we characterize the physical properties of mechanical pr
Autor:
Donata Maciaczyk, Tomasz Bogiel, Charles G. Eberhart, Ulf Dietrich Kahlert, Guido Nikkhah, Eli E. Bar, Jaroslaw Maciaczyk, Noemi Bender
Publikováno v:
Folia neuropathologica. 50(4)
Glioblastoma multiforme (GBM), as many other solid tumours, contains a subpopulation of cells termed cancer stem-like cells responsible for the initiation and propagation of tumour growth. However, a unique immunophenotype/surface antigen composition