Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Donall Forde"'
Autor:
Alvina G. Lai, Wai Hoong Chang, Constantinos A. Parisinos, Michail Katsoulis, Ruth M. Blackburn, Anoop D. Shah, Vincent Nguyen, Spiros Denaxas, George Davey Smith, Tom R. Gaunt, Krishnarajah Nirantharakumar, Murray P. Cox, Donall Forde, Folkert W. Asselbergs, Steve Harris, Sylvia Richardson, Reecha Sofat, Richard J. B. Dobson, Aroon Hingorani, Riyaz Patel, Jonathan Sterne, Amitava Banerjee, Alastair K. Denniston, Simon Ball, Neil J. Sebire, Nigam H. Shah, Graham R. Foster, Bryan Williams, Harry Hemingway
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background An Informatics Consult has been proposed in which clinicians request novel evidence from large scale health data resources, tailored to the treatment of a specific patient. However, the availability of such consultations is lackin
Externí odkaz:
https://doaj.org/article/78307b29f564469e8cd433172aa802e4
Autor:
Xiaodong Zhuang, Donall Forde, Senko Tsukuda, Valentina D’Arienzo, Laurent Mailly, James M. Harris, Peter A. C. Wing, Helene Borrmann, Mirjam Schilling, Andrea Magri, Claudia Orbegozo Rubio, Robert J. Maidstone, Mudassar Iqbal, Miguel Garzon, Rosalba Minisini, Mario Pirisi, Sam Butterworth, Peter Balfe, David W. Ray, Koichi Watashi, Thomas F. Baumert, Jane A. McKeating
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The circadian factors BMAL1/CLOCK and REV-ERB are master regulators of the human liver transcriptome but their role in hepatitis B virus infection is largely unknown. Here, Zhuang et al. show that REV-ERB regulates hepatitis B virus entry and BMAL1 d
Externí odkaz:
https://doaj.org/article/6a8ef38d436d4d3fbb7a5a30aa9a40f8
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Despite much progress in cancer research, its incidence and mortality continue to rise. A robust biomarker that would predict tumor behavior is highly desirable and could improve patient treatment and prognosis. Methods In a retro
Externí odkaz:
https://doaj.org/article/d20a81dcb493407e88ef60332547592c
Autor:
Isa Murrell, Donall Forde, Wioleta Zelek, Linda Tyson, Lisa Chichester, Nicki Palmer, Rachel Jones, B Paul Morgan, Catherine Moore
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245382 (2021)
Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve. Hence, defining the events o
Externí odkaz:
https://doaj.org/article/b233049e2a27452e9f692293a8e0f207
Autor:
Anna L McNaughton, José Lourenço, Phillip Armand Bester, Jolynne Mokaya, Sheila F Lumley, Uri Obolski, Donall Forde, Tongai G Maponga, Kenneth R Katumba, Dominique Goedhals, Sunetra Gupta, Janet Seeley, Robert Newton, Ponsiano Ocama, Philippa C Matthews
Publikováno v:
PLoS Medicine, Vol 17, Iss 4, p e1003068 (2020)
BackgroundInternational Sustainable Development Goals (SDGs) for elimination of hepatitis B virus (HBV) infection set ambitious targets for 2030. In African populations, infant immunisation has been fundamental to reducing incident infections in chil
Externí odkaz:
https://doaj.org/article/55148311f9ac47a5a6a659097cce117d
Autor:
Alvina G. Lai, Donall Forde, Wai Hoong Chang, Fang Yuan, Xiaodong Zhuang, Claudia Orbegozo Rubio, Chun-Xiao Song, Jane A. McKeating
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Background: Little is known about the impact of nutrients on cellular transcriptional responses, especially in face of environmental stressors such as oxygen deprivation. Hypoxia-inducible factors (HIF) coordinate the expression of genes essential fo
Externí odkaz:
https://doaj.org/article/b6f41b16619e420f8a9312c6b666a092
Autor:
Anoop D. Shah, Constantinos A. Parisinos, Wai Hoong Chang, G Davey Smith, Benedict Williams, Sion Kim Harris, Harry Hemingway, Ruth Blackburn, Tom R. Gaunt, S. Ball, Richard Dobson, Reecha Sofat, Vincent Nguyen, Donall Forde, Alastair K Denniston, Alvina G. Lai, Folkert W. Asselbergs, Ami Banerjee, Sylvia Richardson, Jonathan A C Sterne, Spiros Denaxas, Nigam H. Shah, Graham R. Foster, Riyaz S. Patel, Murray P. Cox, Krishnarajah Nirantharakumar, Neil J. Sebire, Aroon D. Hingorani, Michail Katsoulis
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Medical Informatics and Decision Making
BMC Medical Informatics and Decision Making
Background An Informatics Consult has been proposed in which clinicians request novel evidence from large scale health data resources, tailored to the treatment of a specific patient. However, the availability of such consultations is lacking. We see
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18628a579ff8f64de9f32c7c8c4cd66d
https://www.repository.cam.ac.uk/handle/1810/329308
https://www.repository.cam.ac.uk/handle/1810/329308
Autor:
Alvina Lai, Wai Hoong Chang, Parisinos, Constantinos A., Michail Katsoulis, Ruth Blackburn, Anoop Shah, Vincent Nguyen, Spiros Denaxas, George Davey Smith, Tom Gaunt, Krishnarajah Nirantharakumar, Cox, Murray P., Donall Forde, Asselbergs, Folkert W., Steve Harris, Sylvia Richardson, Reecha Sofat, Dobson, Richard R. H., Hingorani, Aroon D., Patel, Riyaz S., Jonathan Sterne, Amitava Banerjee, Denniston, Alastair K. O., Simon Ball, Neil Sebire, Nigam Shah, Graham Foster, Bryan Williams, Harry Hemingway
Publikováno v:
Lai, A, Hoong Chang, W, Parisinos, C A, Katsoulis, M, Blackburn, R, Shah, A, Nguyen, V, Denaxas, S, Davey Smith, G, Gaunt, T R, Nirantharakumar, K, Cox, M P, Forde, D, Asselbergs, F W, Harris, S, Richardson, S, Sofat, R, Dobson, R R H, Hingorani, A D, Patel, R S, Sterne, J A C, Banerjee, A, Denniston, A K O, Denniston, A K O, Ball, S, Sebire, N, Shah, N, Foster, G, Williams, B & Hemingway, H 2021, ' An Informatics Consult approach for generating clinical evidence for treatment decisions ', BMC Medical Informatics and Decision Making, vol. 21, 281 .
University of Bristol-PURE
University of Bristol-PURE
Background: An Informatics Consult has been proposed in which clinicians request novel evidence from large scale health data resources, tailored to the treatment of a specific patient. However, the availability of such consultations is lacking. We se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::55455b51c1433a183d26a243371cb1d3
https://hdl.handle.net/1983/e00b330e-e419-4f3a-954c-f28ad4edfffe
https://hdl.handle.net/1983/e00b330e-e419-4f3a-954c-f28ad4edfffe
Autor:
Linda Tyson, Lisa Chichester, Rachel Jones, Wioleta M. Zelek, B. Paul Morgan, Donall Forde, Catherine Moore, Isa Murrell, Nicki Palmer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0245382 (2021)
PLoS ONE, Vol 16, Iss 1, p e0245382 (2021)
Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve. Hence, defining the events o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f16cbac287511fe75c53dc7c4951e2
http://europepmc.org/articles/PMC7837461
http://europepmc.org/articles/PMC7837461
Autor:
Linda Tyson, Catherine Moore, Nicki Palmer, Lisa Chichester, Owen Vineall, Isa Murrell, Donall Forde, Anna Garratt, Rachel Jones
There is a requirement for easily accessible, high throughput serological testing as part of the SARS-CoV-2 pandemic response. Whilst of limited diagnostic use in an acute individual setting, its use on a population level is key to informing a cohere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6e6ddca5ce31f3d6c1685e4083606f
https://doi.org/10.1101/2020.10.29.20219931
https://doi.org/10.1101/2020.10.29.20219931