Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Donald Van Ryk"'
Autor:
Sinmanus Vimonpatranon, Livia R Goes, Amanda Chan, Isabella Licavoli, Jordan McMurry, Samuel R Wertz, Anush Arakelyan, Dawei Huang, Andrew Jiang, Cindy Huang, Joyce Zhou, Jason Yolitz, Alexandre Girard, Donald Van Ryk, Danlan Wei, Il Young Hwang, Craig Martens, Kishore Kanakabandi, Kimmo Virtaneva, Stacy Ricklefs, Benjamin P Darwitz, Marcelo A Soares, Kovit Pattanapanyasat, Anthony S Fauci, James Arthos, Claudia Cicala
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011209 (2023)
CD4+ tissue resident memory T cells (TRMs) are implicated in the formation of persistent HIV reservoirs that are established during the very early stages of infection. The tissue-specific factors that direct T cells to establish tissue residency are
Externí odkaz:
https://doaj.org/article/dbbfe6462eef488fb4eecaebbb698732
Autor:
Isabela Silva de Castro, Giacomo Gorini, Rosemarie Mason, Jason Gorman, Massimiliano Bissa, Mohammad A. Rahman, Anush Arakelyan, Irene Kalisz, Stephen Whitney, Manuel Becerra-Flores, Eric Ni, Kristina Peachman, Hung V. Trinh, Michael Read, Mei-Hue Liu, Donald Van Ryk, Dominic Paquin-Proulx, Zhanna Shubin, Marina Tuyishime, Jennifer Peele, Mohammed S. Ahmadi, Raffaello Verardi, Juliane Hill, Margaret Beddall, Richard Nguyen, James D. Stamos, Dai Fujikawa, Susie Min, Luca Schifanella, Monica Vaccari, Veronica Galli, Melvin N. Doster, Namal P.M. Liyanage, Sarkis Sarkis, Francesca Caccuri, Celia LaBranche, David C. Montefiori, Georgia D. Tomaras, Xiaoying Shen, Margherita Rosati, Barbara K. Felber, George N. Pavlakis, David J. Venzon, William Magnanelli, Matthew Breed, Josh Kramer, Brandon F. Keele, Michael A. Eller, Claudia Cicala, James Arthos, Guido Ferrari, Leonid Margolis, Marjorie Robert-Guroff, Peter D. Kwong, Mario Roederer, Mangala Rao, Timothy J. Cardozo, Genoveffa Franchini
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102047- (2021)
Summary: The efficacy of ALVAC-based HIV and SIV vaccines in humans and macaques correlates with antibodies to envelope variable region 2 (V2). We show here that vaccine-induced antibodies to SIV variable region 1 (V1) inhibit anti-V2 antibody-mediat
Externí odkaz:
https://doaj.org/article/0f4c13b40f5b4bb9bf78e5a35a226d78
Autor:
Raffaello Cimbro, Francis C. Peterson, Qingbo Liu, Christina Guzzo, Peng Zhang, Huiyi Miao, Donald Van Ryk, Xavier Ambroggio, Darrell E. Hurt, Luca De Gioia, Brian F. Volkman, Michael A. Dolan, Paolo Lusso
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 45-54 (2016)
Tyrosine sulfation is a post-translational modification that facilitates protein-protein interaction. Two sulfated tyrosines (Tys173 and Tys177) were recently identified within the second variable (V2) loop of the major HIV-1 envelope glycoprotein, g
Externí odkaz:
https://doaj.org/article/ce81977be5dd413dbb5122f23811cdf3
Autor:
Sakaorat Lertjuthaporn, Claudia Cicala, Donald Van Ryk, Matthew Liu, Jason Yolitz, Danlan Wei, Fatima Nawaz, Allison Doyle, Brooke Horowitch, Chung Park, Shan Lu, Yang Lou, Shixia Wang, Ruimin Pan, Xunqing Jiang, Francois Villinger, Siddappa N Byrareddy, Philip J Santangelo, Lynn Morris, Constantinos Kurt Wibmer, Kristin Biris, Rosemarie D Mason, Jason Gorman, Joseph Hiatt, Elena Martinelli, Mario Roederer, Dai Fujikawa, Giacomo Gorini, Genoveffa Franchini, Anush Arakelyan, Aftab A Ansari, Kovit Pattanapanyasat, Xiang-Peng Kong, Anthony S Fauci, James Arthos
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007278 (2018)
The GI tract is preferentially targeted during acute/early HIV-1 infection. Consequent damage to the gut plays a central role in HIV pathogenesis. The basis for preferential targeting of gut tissues is not well defined. Recombinant proteins and synth
Externí odkaz:
https://doaj.org/article/1d27a974a42f4d20a2e0217100ce0387
Autor:
Fatima Nawaz, Claudia Cicala, Donald Van Ryk, Katharine E Block, Katija Jelicic, Jonathan P McNally, Olajumoke Ogundare, Massimiliano Pascuccio, Nikita Patel, Danlan Wei, Anthony S Fauci, James Arthos
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001301 (2011)
Mucosal transmission of HIV is inefficient. The virus must breach physical barriers before it infects mucosal CD4+ T cells. Low-level viral replication occurs initially in mucosal CD4+ T cells, but within days high-level replication occurs in Peyer's
Externí odkaz:
https://doaj.org/article/8784641fb4874ee6932b21860cd590a8
Autor:
Elena Martinelli, Claudia Cicala, Jocelyn C Ray, Marcelo A. Soares, James Arthos, Donald Van Ryk, Mark Connors, Mia Waliszewski, Joseph Hiatt, Danlan Wei, Francois Villinger, Aftab A. Ansari, Ian Perrone, Fatima Nawaz, Stephen A. Migueles, Alia Sajani, Ronke Olowojesiku, Anthony S. Fauci, Katija Jelicic, Livia R. Goes
Publikováno v:
Mucosal Immunology. 11:1342-1351
Human gut-associated lymphoid tissues (GALT) play a key role in the acute phase of HIV infection. The propensity of HIV to replicate in these tissues, however, is not fully understood. Access and migration of naive and memory CD4+ T cells to these si
Autor:
Julia Chang, Anthony S. Fauci, Claudia Cicala, Jason Yolitz, Catherine Schwing, Fatima Nawaz, Danlan Wei, Donald Van Ryk, James Arthos
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Significant heterogeneity exists in the structure and antigenicity of HIV-1 envelope protein (Env) gp120 due, in part, to various posttranslational modifications. Using glycan and antigenic analysis, we show that the signal peptide (SP)
Autor:
Brian F. Volkman, Raffaello Cimbro, Xavier Ambroggio, Francis C. Peterson, Luca De Gioia, Paolo Lusso, Peng Zhang, Darrell E. Hurt, Christina Guzzo, Donald Van Ryk, Huiyi Miao, Qingbo Liu, Michael A. Dolan
Publikováno v:
EBioMedicine
EBioMedicine, Vol 10, Iss C, Pp 45-54 (2016)
EBioMedicine, Vol 10, Iss C, Pp 45-54 (2016)
Tyrosine sulfation is a post-translational modification that facilitates protein-protein interaction. Two sulfated tyrosines (Tys173 and Tys177) were recently identified within the second variable (V2) loop of the major HIV-1 envelope glycoprotein, g
Autor:
Kovit Pattanapanyasat, Jason Gorman, Philip J. Santangelo, Sakaorat Lertjuthaporn, Aftab A. Ansari, Siddappa N. Byrareddy, Jason Yolitz, Constantinos Kurt Wibmer, Lynn Morris, Matthew Liu, Elena Martinelli, Mario Roederer, Donald Van Ryk, Francois Villinger, Danlan Wei, Yang Lou, Dai Fujikawa, Ruimin Pan, Anthony S. Fauci, James Arthos, Genoveffa Franchini, Allison Doyle, Shan Lu, Claudia Cicala, Xiang-Peng Kong, Giacomo Gorini, Joseph Hiatt, Fatima Nawaz, Xunqing Jiang, Chung Park, Kristin K. Biris, Rosemarie D. Mason, Brooke Horowitch, Shixia Wang, Anush Arakelyan
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007278 (2018)
The GI tract is preferentially targeted during acute/early HIV-1 infection. Consequent damage to the gut plays a central role in HIV pathogenesis. The basis for preferential targeting of gut tissues is not well defined. Recombinant proteins and synth
Autor:
Fatima, Nawaz, Livia R, Goes, Jocelyn C, Ray, Ronke, Olowojesiku, Alia, Sajani, Aftab A, Ansari, Ian, Perrone, Joseph, Hiatt, Donald, Van Ryk, Danlan, Wei, Mia, Waliszewski, Marcelo A, Soares, Katija, Jelicic, Mark, Connors, Stephen A, Migueles, Elena, Martinelli, Francois, Villinger, Claudia, Cicala, Anthony S, Fauci, James, Arthos
Publikováno v:
Mucosal immunology
Human gut associated lymphoid tissues (GALT) play a key role in the acute phase of HIV infection. The propensity of HIV to replicate in these tissues however, is not fully understood. Access and migration of naïve and memory CD4+ T cells to these si