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pro vyhledávání: '"Donald Tope"'
Autor:
Donald Tope, Branella Gianna, Erich Williams, H. Trent Spencer, Christopher B. Doering, Rebecca E. Burnham
Publikováno v:
Cryobiology
Clinical applications of gamma delta (γδ) T cells have advanced from initial interest in expanding γδ T cells in vivo to the development of a manufacturing process for the ex vivo expansion. To develop an "off-the-shelf" allogeneic γδ T cell pr
Publikováno v:
Blood. 138:3312-3312
Background: Leukemia is the most common type of childhood cancer. Although the prognosis for many pediatric leukemias has improved, leukemias associated with the t(10;11) CALM-AF10 translocation remain difficult to treat. CALM-AF10 leukemias account
Autor:
Hengbo Zhou, Catherine Lavau, Heide L. Ford, Amanda Harrington, Waitman K. Aumann, Amanda E. Conway, Donald Tope, Daniel S. Wechsler
Publikováno v:
Blood. 136:38-39
Background : The CALM-AF10 translocation is found 5-10% of T-cell acute lymphoblastic leukemias (T-ALL), and a subset of acute myeloid leukemias (AML). CALM-AF10 leukemias are characterized by elevated expression of proleukemic HOXA genes. Since HOXA