Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Donald T. Gracias"'
Autor:
Jennifer L. Hope, Christopher J. Stairiker, Panagiota I. Spantidea, Donald T. Gracias, Alison J. Carey, Adam J. Fike, Marjan van Meurs, Inge Brouwers-Haspels, Laurine C. Rijsbergen, Joseph A. Fraietta, Yvonne M. Mueller, Rosemarieke C. Klop, Erietta Stelekati, E. John Wherry, Stefan J. Erkeland, Peter D. Katsikis
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
We report here that the expression of the transcription factor T-bet, which is known to be required for effector cytotoxic CD8+ T lymphocytes (CTL) generation and effector memory cell formation, is regulated in CTL by microRNA-155 (miR-155). Importan
Externí odkaz:
https://doaj.org/article/045e79ae899f4457b4050ae3c4bfc370
Autor:
Gurupreet S. Sethi, Donald T. Gracias, Rinkesh K. Gupta, Daniel Carr, Haruka Miki, Ricardo Da Silva Antunes, Michael Croft
Publikováno v:
Allergy.
Autor:
Amit Mehta, Donald T. Gracias, Rinkesh K. Gupta, Gurupreet S. Sethi, Hideo Yagita, Haruka Miki, Michael Croft
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:2316-2329
Background The selective reduction of memory TH2 cell responses could be key to affording tolerance and protection from the recurrence of damaging allergic pathology. Objective We asked whether TNF family costimulatory molecules cooperated to promote
Autor:
Joseph S, Dolina, Joey, Lee, Eugene L, Moore, Jennifer L, Hope, Donald T, Gracias, Takaji, Matsutani, Ashu, Chawla, Jason A, Greenbaum, Joel, Linden, Stephen P, Schoenberger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(10)
SignificanceThe CD4
Autor:
Joseph S. Dolina, Joey Lee, Eugene L. Moore, Jennifer L. Hope, Donald T. Gracias, Takaji Matsutani, Ashu Chawla, Jason A. Greenbaum, Joel Linden, Stephen P. Schoenberger
Publikováno v:
Proceedings of the National Academy of Sciences. 119
SignificanceThe CD4+Tregresponse following acuteListeriainfection is heterogeneous and deploys two distinct modes of suppression coinciding with initial pathogen exposure and resolution of infection. This bimodal suppression of CD8+T cells during pri
Autor:
Michael Croft, Donald T. Gracias, Kai Fung, Linda C. Burkly, Jacqueline Miller, Ferhat Ay, Haruka Miki, Daniela Salgado Figueroa, Rinkesh K. Gupta
Publikováno v:
Sci Immunol
TNF and IL-17 are two cytokines that drive dysregulated keratinocyte activity and their targeting is highly efficacious in psoriasis patients, but whether these molecules act with other inflammatory factors is not clear. Here, we show that mice posse
Autor:
Donald T, Gracias, Gurupreet S, Sethi, Amit K, Mehta, Haruka, Miki, Rinkesh K, Gupta, Hideo, Yagita, Michael, Croft
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: The selective reduction of memory Th2 responses could be key to affording tolerance and protection from the reoccurrence of damaging allergic pathology. OBJECTIVE: We asked whether TNF family costimulatory molecules co-operated to promote
Publikováno v:
J Allergy Clin Immunol
Background Poor clearance of apoptotic cells has been suggested to contribute to severe asthma, but whether uptake of apoptotic cells by lung phagocytes might dampen house dust mite (HDM)-induced lung inflammation has not been shown. Objectives This
Publikováno v:
Cytokine. 101:14-18
TNF (tumor necrosis factor) is both a pro-inflammatory and anti-inflammatory cytokine that is central to the development of autoimmune disease, cancer, and protection against infectious pathogens. As well as a myriad other activities, TNF can be a pr