Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Donald T. Lysle"'
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100542- (2022)
Post-traumatic stress disorder (PTSD) is a devastating disorder that involves maladaptive changes in immune status. Using the stress-enhanced fear learning (SEFL) paradigm, an animal model of PTSD, our laboratory has demonstrated increased pro-inflam
Externí odkaz:
https://doaj.org/article/afc34957685844608a86d8b936259dce
Publikováno v:
Psychopharmacology. 240:347-359
Post-traumatic stress disorder (PTSD) and opioid use disorder (OUD) are comorbid in clinical populations. However, both pre-clinical and clinical studies of these co-occurring disorders have disproportionately represented male subjects, limiting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ca850a836c3e9289f3b2eea2214d91
https://doi.org/10.1007/s00213-023-06310-0
https://doi.org/10.1007/s00213-023-06310-0
Autor:
Gillian A. Barkell, Shveta V. Parekh, Jacqueline E. Paniccia, Alia J. Martin, Kathryn J. Reissner, Darin J. Knapp, Stacey L. Robinson, Todd E. Thiele, Donald T. Lysle
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:2177-2190
Alcohol use disorder (AUD) and post-traumatic stress disorder (PTSD) are highly comorbid, yet there is a lack of preclinical research investigating how prior ethanol (EtOH) dependence influences the development of a PTSD-like phenotype. Furthermore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049e72879baf5e381aa1cb54442faf14
https://doi.org/10.1111/acer.14963
https://doi.org/10.1111/acer.14963
Publikováno v:
Molecular Neurobiology
There is significant comorbidity of opioid use disorder (OUD) and post-traumatic stress disorder (PTSD) in clinical populations. However, the neurobiological mechanisms underlying the relationship between chronic opioid use and withdrawal and develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6fa53a2a0248ecbeeab9daf80073c8
https://doi.org/10.1007/s12035-021-02322-z
https://doi.org/10.1007/s12035-021-02322-z
Publikováno v:
Brain Behav Immun
Opioids and opioid-conditioned stimuli (CS) negatively alter host immunity, impairing the response to pathogens during opioid use and following drug cessation. Using male rats, our laboratory has determined that heroin or heroin-CS exposure preceding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbccd09c9ad2b77bc62a2cd0e7dbc99
https://europepmc.org/articles/PMC7749831/
https://europepmc.org/articles/PMC7749831/
Publikováno v:
Psychopharmacology (Berl)
Converging evidence suggests opioid abuse can increase the incidence and severity of post-traumatic stress disorder (PTSD) in clinical populations. Interestingly, opioid withdrawal alone can produce symptoms similar to those of PTSD. Despite this ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d23c2a476e23f2ab07d17ab0062cc7
https://europepmc.org/articles/PMC7686097/
https://europepmc.org/articles/PMC7686097/
Autor:
Douglas J. Hermes, Ken Mackie, Nichole Reisdorph, Benjamin F. Cravatt, Jacqueline E. Paniccia, Donald T. Lysle, Sylvia Fitting, Barkha J. Yadav-Samudrala, Rick B. Meeker, Changqing Xu, Aron H. Lichtman, Michael Armstrong, Bogna M. Ignatowska-Jankowska
Publikováno v:
Experimental neurology. 341
Human immunodeficiency virus type 1 (HIV-1) is known to provoke microglial immune responses which likely play a paramount role in the development of chronic neuroinflammatory conditions and neuronal damage related to HIV-1 associated neurocognitive d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba793bb8350c09641cbefcf97f4ef680
https://pubmed.ncbi.nlm.nih.gov/33736974
https://pubmed.ncbi.nlm.nih.gov/33736974
Autor:
Meghan E. Jones, Christina L. Lebonville, Rita A. Fuchs, Lynde M. Wangler, Jacqueline E. Paniccia, Shveta V. Parekh, Donald T. Lysle
Publikováno v:
Brain Behav Immun
The physiological and motivational effects of heroin and other abused drugs become associated with environmental (contextual) stimuli during repeated drug use. As a result, these contextual stimuli gain the ability to elicit drug-like conditioned eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff490d3911fe86a73cea2e3c2800cc5f
https://pubmed.ncbi.nlm.nih.gov/32717403
https://pubmed.ncbi.nlm.nih.gov/32717403
Autor:
Scot McIntosh, S. Alex Marshall, Donald T. Lysle, Todd E. Thiele, Isabella R. Grifasi, Rhiannon D Thomas
Publikováno v:
Neuroimmunomodulation. 26:19-32
Objectives: Alcohol dependence leads to dysregulation of the neuroimmune system, but the effects of excessive alcohol consumption on key players of the neuroimmune response after episodic binge drinking in nondependence has not been readily assessed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1b7d7bfc0370834d282e77e6194c25
https://doi.org/10.1159/000495210
https://doi.org/10.1159/000495210
Autor:
Rita A. Fuchs, Shveta V. Parekh, Donald T. Lysle, Jacqueline E. Paniccia, Meghan E. Jones, Christina L. Lebonville
Publikováno v:
Brain, Behavior, and Immunity. 73:698-707
Repeated pairings of heroin and a context results in Pavlovian associations which manifest as heroin-conditioned appetitive responses and peripheral immunomodulation upon re-exposure to heroin-paired conditioned stimuli (CS). The dorsal hippocampus (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0acd35d9ec9689db0266137ff37233
https://doi.org/10.1016/j.bbi.2018.07.024
https://doi.org/10.1016/j.bbi.2018.07.024