Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Donald Smyth"'
Autor:
Matthew J. Schiewer, Susana Miranda, William West, Suzanne Carreira, Stuart Thomson, Gareth W. Harbottle, Ana Ferreira, Stuart Thomas Onions, Donald Smyth, Nigel Brooks, Jonathan Shannon, Jonathan Welti, Nina Tunariu, Johann S. de Bono, Christopher McNair, Jenny Worthington, Wei Yuan, Karen E. Knudsen, Adam Sharp, Barbara Young, Amy Prosser, Jan Rekowski, Su C, Rita Pereira, Amanda Swain, Jian Ning, Abhijit Pal, Jordan Lane, Ruth Riisnaes, Bora Gurel, Ines Figueiredo, Mateus Crespo, Richard J. C. Brown, Saswati N. Chand, David Michel Adrien Taddei, Denisa Bogdan, Veronica Gil, Silvia Paoletta, Meera Raja, Neil Anthony Pegg, Antje Neeb
Publikováno v:
Cancer discovery. 11(5)
Resistance to androgen receptor (AR) blockade in castration-resistant prostate cancer (CRPC) is associated with sustained AR signaling, including through alternative splicing of AR (AR-SV). Inhibitors of transcriptional coactivators that regulate AR
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2840-2849
The synthesis of a series of closely related mono- and bis(diazaphospholidine) ligands has been achieved using the condensation of a diamine with a bis(dimethylamino)arylphosphine. The resulting ligands have given excellent results in palladium-catal
Publikováno v:
Applied Organometallic Chemistry. 15:16-22
The analysis of patterns of regioselectivity in cyclohexadienyl complexes illustrates the versatility and power of the iron-based methodology in reaction sequences that make multiple use of the metal to establish a series of chiral centres, The conve
Publikováno v:
Tetrahedron Letters. 39:7603-7606
The protonation of prochiral exocyclic double bonds in cyclohexa-2,4-dieneiron(0) complexes introduces a chiral centre adjacent to the emergent η 5 -cyclohexadienyliron(1+) portion of the product. This reaction has been shown to be fully diastereose
Publikováno v:
Tetrahedron Letters. 38:505-508
Diastereoselective addition of nucleophiles to 1-(RCO)-substituted tricarbony η 4 -cyclohexadiene)iron(0) complexes, and a diastereoselective acid-induced rearrangement to form 1-(branched alkyl)-substituted tricarbonyl( η 5 -cyclohexadienyl)iron(1
Publikováno v:
Tetrahedron Letters. 37:2731-2734
Optimisation of Stille coupling between tricarbonyl[1,2,3,4-η-cyclohexadien-1-yl triflate]iron(0) and tributylvinyltin forms the 1-ethenyl-substituted tricarbonyliron complex in up to 81% yield. Coupling with trimethylsilylethyne in the presence of
Publikováno v:
ChemInform. 28
Publikováno v:
ChemInform. 29
Publikováno v:
ChemInform. 33
The synthesis of a series of closely related mono- and bis(diazaphospholidine) ligands has been achieved using the condensation of a diamine with a bis(dimethylamino)arylphosphine. The resulting ligands have given excellent results in palladium-catal
Autor:
Richard C. D. Brown, David C. Harrowven, Gordon Bruton, Donald Smyth, Nigel A. Swain, Paul S. Skerry
Publikováno v:
Chem. Commun.. :1772-1773
A new approach to the diastereoselective synthesis of thienofuranones is described in which an intramolecular 1,5-carbenoid C-H insertion adjacent to sulfur features as a key step.