Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Donald S. Walter"'
Publikováno v:
European Journal of Pharmacology. 187:531-536
An investigation has been made of the effects of the selective alpha 2-adrenoceptor antagonist, idazoxan, on the plasma immunoreactive insulin and glucose responses following a glucose stimulus in conscious euglycaemic rats. UK 14304 (100 micrograms/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d129702376535c4f729b37aa0f4bdc4
https://doi.org/10.1016/0014-2999(90)90382-g
https://doi.org/10.1016/0014-2999(90)90382-g
Publikováno v:
Biochemical Pharmacology. 32:3122-3125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f617aef4580728e86f60b42be55ce12
https://doi.org/10.1016/0006-2952(83)90261-7
https://doi.org/10.1016/0006-2952(83)90261-7
Publikováno v:
Journal of Medicinal Chemistry. 29:2280-2284
This paper describes the synthesis and pharmacological evaluation of a number evaluation of a number of substituted 1,3,4-thiadiazoles. The first member of the series, 2-(aminomethyl)-5-(2-biphenylyl)-1,3,4-thiadiazole (7) was found to possess potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4396783901cbdda2ff45591fb279d9b
https://doi.org/10.1021/jm00161a025
https://doi.org/10.1021/jm00161a025
Publikováno v:
European Journal of Pharmacology. 69:147-153
The effect of a wide range of doses of buprenorphine (0.001–10 mg·kg−1, s.c.), a partial agonist at mu (μ) oipiate receptors, was studied on (a) the steady state levels of dopamine, noradrenaline, 5-hydroxytryptamine, homovanillic acid, 3-methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40775097df2a2b3a521d18a4affc150c
https://doi.org/10.1016/0014-2999(81)90409-x
https://doi.org/10.1016/0014-2999(81)90409-x
Autor:
Rodolfo E. Ballester, Fred W. Blaisdell, John Wallace Ridley, Donald S. Walter, Bernard Donelan
Publikováno v:
Transactions of the American Society of Civil Engineers. 121:334-342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ddbbcf87560f31c5b8ba374a981a875
https://doi.org/10.1061/taceat.0007297
https://doi.org/10.1061/taceat.0007297
Publikováno v:
Biochemical Society transactions. 6(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cd620e6210c76093802b821aabda6a
https://pubmed.ncbi.nlm.nih.gov/744302
https://pubmed.ncbi.nlm.nih.gov/744302
Autor:
Malcolm Myers, Peter Myers, John F. Saville, Donald S. Walter, Christopher B. Chapleo, Michael R. Stillings, Ian F. Tulloch, Alan C. B. Smith, Anthony P. Welbourn
Publikováno v:
Journal of medicinal chemistry. 29(11)
The synthesis and anticonvulsant activity of a series of 2-aryl-5-hydrazino-1,3,4-thiadiazoles are described. The combination of preferred aromatic substituents in the 2-position coupled with alkyl substitution on the hydrazine moiety led to a number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb12081b5708ae78033f0bca7090e41a
https://pubmed.ncbi.nlm.nih.gov/3783589
https://pubmed.ncbi.nlm.nih.gov/3783589
Autor:
Gillian M. Shilcock, Donald S. Walter
Publikováno v:
The Journal of pharmacy and pharmacology. 29(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56da1f83baa018f74b4105f6051e3443
https://pubmed.ncbi.nlm.nih.gov/21243
https://pubmed.ncbi.nlm.nih.gov/21243
Autor:
Ian F. Tulloch, Alan C. B. Smith, Christopher B. Chapleo, Peter Myers, Michael R. Stillings, Donald S. Walter
Publikováno v:
Journal of medicinal chemistry. 31(1)
Two different structural types of 2-aryl-1,3,4-thiadiazole amidines were synthesized and evaluated for anticonvulsant activity. Enhancement of the inherent anticonvulsant activity therein and separation of this activity from the accompanying sedative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e0a31c5551c8a2df56f9830ac3dbbe
https://pubmed.ncbi.nlm.nih.gov/3336034
https://pubmed.ncbi.nlm.nih.gov/3336034
Autor:
Donald S. Walter, Ian R. Flockhart, John Johnson, Anthony C. Lane, Richard Burton, Margaret J. Haynes, Peter W. Dettmar, David R. Howlett
Publikováno v:
Biochemical pharmacology. 33(16)
Experiments have been performed to assess the potency of idazoxan (RX 781094) at alpha and beta-adrenoceptors and dopamine receptors and on catecholamine uptake processes in rat brain. The effects of idazoxan on the turnover rates of noradrenaline an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30a9dbd5099dfc91a09b18102b320e1
https://pubmed.ncbi.nlm.nih.gov/6147143
https://pubmed.ncbi.nlm.nih.gov/6147143