Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Donald S. Sakaguchi"'
Autor:
Bhavika B. Patel, Marilyn C. McNamara, Laura S. Pesquera-Colom, Emily M. Kozik, Jasmin Okuzonu, Nicole N. Hashemi, Donald S. Sakaguchi
Publikováno v:
ACS Omega, Vol 5, Iss 14, Pp 7910-7918 (2020)
Externí odkaz:
https://doaj.org/article/0d3d00fcff16465ea187eb5c5ad9ffe4
Autor:
Najiba Mammadova, Corey M. Summers, Robyn D. Kokemuller, Qing He, Shaowei Ding, Thierry Baron, Chenxu Yu, Rudy J. Valentine, Donald S. Sakaguchi, Anumantha G. Kanthasamy, Justin J. Greenlee, M. Heather West Greenlee
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 1-16 (2019)
Parkinson's disease (PD) is a neurodegenerative disorder characterized by accumulation of misfolded α-synuclein within the central nervous system (CNS). Visual problems in PD patients are common, although retinal pathology associated with PD is not
Externí odkaz:
https://doaj.org/article/0866e59c39c44f0eb2dd5238873737de
Autor:
Subin Mao, Catherine Fonder, Md Fazlay Rubby, Gregory J. Phillips, Donald S. Sakaguchi, Long Que
Publikováno v:
Lab on a Chip. 23:1649-1663
To improve our understanding of how the central nervous system functions, we report the development of an integrated chip for studying the effects of the neurotransmitters on adult rat hippocampal progenitor cell neurospheroids.
Autor:
Renyuan Yang, Catherine Fonder, Talia Sylvester, Stefan Peng, David Jiles, Donald S. Sakaguchi, Long Que
Publikováno v:
Journal of Microelectromechanical Systems. 31:37-44
Autor:
Donald S. Sakaguchi, S. Jo Moore, M. Heather West Greenlee, Najiba Mammadova, Justin J. Greenlee
Publikováno v:
The American Journal of Pathology. 190:1461-1473
Proteinopathies result from aberrant folding and accumulation of specific proteins. Currently, there is a lack of knowledge about the factors that influence disease progression, making this a key challenge for the development of therapies for protein
Autor:
Donald S. Sakaguchi, Marilyn C. McNamara, Laura S Pesquera-Colom, Jasmin Okuzonu, Nicole N. Hashemi, Emily M. Kozik, Bhavika B. Patel
Publikováno v:
ACS Omega, Vol 5, Iss 14, Pp 7910-7918 (2020)
ACS Omega
ACS Omega
Because of the limitations imposed by traditional two-dimensional (2D) cultures, biomaterials have become a major focus in neural and tissue engineering to study cell behavior in vitro. 2D systems fail to account for interactions between cells and th
Autor:
Juhyung Jung, Maxsam S. Donta, Surya K. Mallapragada, John A. Hondred, Donald S. Sakaguchi, Elizabeth J. Sandquist, Jonathan C. Claussen, Metin Uz, Emily M. Kozik, Jonathan Green
Publikováno v:
Regenerative Engineering and Translational Medicine. 6:18-28
This study investigated the effect of electrical stimuli parameters using graphene-based devices for the transdifferentiation of genetically engineered brain-derived neurotrophic factor (BDNF) hypersecreting mesenchymal stem cells (BDNF-MSCs) into ne
Autor:
Nicole N. Hashemi, Bhavika B. Patel, Mingchang Lu, Marissa N. Roghair, Peter J. Meis, Farrokh Sharifi, Marilyn C. McNamara, Donald S. Sakaguchi, Reza Montazami
Publikováno v:
ACS Applied Materials & Interfaces. 11:18797-18807
Bow tie-shaped fibers and spherical microparticles with controlled dimensions and shapes were fabricated with poly(ethylene glycol) diacrylate hydrogel utilizing hydrodynamic shear principles and a photopolymerization strategy under a microfluidic re
Publikováno v:
Industrial & Engineering Chemistry Research. 58:7421-7427
In this study, gelatin and graphene-based nerve regeneration conduits/scaffolds possessing tailored three-dimensional (3D) microstructures and mechanical properties were fabricated using 3D printin...
Autor:
Staci L Solin, Ying Wang, Joshua Mauldin, Laura E Schultz, Deborah E Lincow, Pavel A Brodskiy, Crystal A Jones, Judith Syrkin-Nikolau, Jasmine M Linn, Jeffrey J Essner, Jesse M Hostetter, Elizabeth M Whitley, J Douglas Cameron, Hui-Hsien Chou, Andrew J Severin, Donald S Sakaguchi, Maura McGrail
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114888 (2014)
In this study we describe the molecular and cellular characterization of a zebrafish mutant that develops tumors in the optic pathway. Heterozygous Tg(flk1:RFP)is18 transgenic adults develop tumors of the retina, optic nerve and optic tract. Molecula
Externí odkaz:
https://doaj.org/article/717a136c648241dfbc1ea4db0391295c