Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Donald R. Wesson"'
Autor:
Donald R. Wesson, David E. Smith
Publikováno v:
Psychiatry. :1549-1560
Publikováno v:
Alcoholism: Clinical & Experimental Research. 28:1051-1059
Background: Studies of the efficacy of naltrexone for alcohol dependence have yielded variable findings, which may be due, in part, to variation in compliance with oral naltrexone. Efforts to improve naltrexone compliance have included the developmen
Autor:
Walter Ling, Donald R. Wesson
Publikováno v:
Journal of Psychoactive Drugs. 35:253-259
The clinical opiate withdrawal scale (COWS) is a clinician-administered, pen and paper instrument that rates eleven common opiate withdrawal signs or symptoms. The summed score of the eleven items can be used to assess a patient's level of opiate wit
Autor:
Walter Ling, Donald R. Wesson
Publikováno v:
Drug and Alcohol Dependence. 70:S49-S57
Buprenorphine has been studied extensively since 1978 when it was initially proposed as an alternative to methadone for treatment of opioid dependence. Early work by Jasinski et al., 1978; Mello and Mendelson, 1980; Mello et al., 1982; Mello et al.,
Autor:
Joseph Collins, Doralie Segal, Laura McNicholas, Steve Batki, Donald R. Wesson, John A. Renner, Paul Casadonte, Donald J. Tusel, Prudencia C. Kintaudi, Lawrence S. Brown, Carol Fye, Charles Charuvastra, Susan M. Stine, Erick Santos, Walter Ling, Richard I. H. Wang, Usha Malkerneker
Publikováno v:
Addiction. 93:475-486
Aims. To evaluate the safety and ef® cacy of an 8 mg/day sublingual dose of buprenorphine in the maintenance treatment of heroin addicts by comparison with a 1 mg/day dose over a 16-week treatment period. As a secondary objective, outcomes were dete
Autor:
Donald R. Wesson
Publikováno v:
Journal of Addictive Diseases. 25:1-3
Publikováno v:
The American Journal on Addictions. 5:220-230
The authors used pharmacological response criteria to determine the therapeutic dose range of buprenorphine for the treatment of opiate dependence. One hundred consecutively admitted patients with opiate addiction were followed for 16 weeks while rec
Publikováno v:
Journal of Psychoactive Drugs. 28:183-189
Flunitrazepam (Rohypnol) is a benzodiazepine sedative-hypnotic that has generated significant media attention in the United States because of its abuse and its association with "date rape." A field investigation was conducted in south Texas to ascert
Publikováno v:
Journal of Addictive Diseases. 15:85-92
Clinical trials designed to establish the effectiveness of a pharmacotherapy for the treatment of drug abuse typically call for the collection and analysis of three urine samples per week to detect changes in drug use patterns. Examination of over 16
Publikováno v:
Journal of Addictive Diseases. 14:97-114
The partial mu-opiate agonist, buprenorphine, is the subject of recent evaluation as a potential pharmacotherapy for cocaine dependence. This paper reviews the extant preclinical and clinical evidence of buprenorphine effectiveness in treating cocain