Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Donald R. Dugger"'
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148773 (2016)
PURPOSE:Bardet-Biedl syndrome is a complex ciliopathy that usually manifests with some form of retinal degeneration, amongst other ciliary-related deficiencies. One of the genetic causes of this syndrome results from a defect in Bardet-Biedl Syndrome
Externí odkaz:
https://doaj.org/article/1a739a90ec1145d5a8331fdc54dbaad3
Autor:
Catherine E. Marten, Todd H. Oakley, Daniel I. Speiser, Spencer R. Saraf, Donald R. Dugger, Barbara-Anne Battelle, Karen E. Kempler
Publikováno v:
The Journal of experimental biology. 218(Pt 3)
The eyes of the horseshoe crab Limulus polyphemus have long been used for studies of basic mechanisms of vision, and the structure and physiology of Limulus photoreceptors have been examined in detail. Less is known about the opsins Limulus photorece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed4fb2c9a64859eb4e1cf084b4d131f
https://pubmed.ncbi.nlm.nih.gov/25524988
https://pubmed.ncbi.nlm.nih.gov/25524988
Publikováno v:
Journal of Experimental Biology.
The eyes of the horseshoe crab, Limulus polyphemus, are a model for studies of visual function and the visual systems of euarthropods. Much is known about the structure and function of Limulus photoreceptors; much less about their photopigments. Thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737a2e3ab3cfea6b1d4e2c87de1c7db7
https://doi.org/10.1242/jeb.107383
https://doi.org/10.1242/jeb.107383
Autor:
Ronald L. Miller, J.H. McDowell, Donald R. Dugger, Anatol Arendt, W. C. Smith, Michael P. Popp, Paul A. Hargrave
Publikováno v:
Biochemistry. 38:2752-2761
Arrestin facilitates phototransduction inactivation through binding to photoactivated and phosphorylated rhodopsin (RP). However, the specific portions of arrestin that bind to RP are not known. In this study, two different approaches were used to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d6034ee25609ff3c3b696dd9d26730
https://doi.org/10.1021/bi982643l
https://doi.org/10.1021/bi982643l
Autor:
Benjamin Spitzbarth, Elisabeth Sehn, J. Hugh McDowell, Tyler S. Smith, W. Clay Smith, Donald R. Dugger, Susan Bolch, Uwe Wolfrum, Gabi Stern-Schneider, Jian Li, Jeremiah D. Tipton
Publikováno v:
Cellular and Molecular Life Sciences; Vol 70
Arrestins are dynamic proteins that move between cell compartments triggered by stimulation of G-protein-coupled receptors. Even more dynamically in vertebrate photoreceptors, arrestin1 (Arr1) moves between the inner and outer segments according to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb05af8943086c327e625ee091f9841
https://europepmc.org/articles/PMC3819411/
https://europepmc.org/articles/PMC3819411/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0148773 (2016)
PLoS ONE, Vol 11, Iss 2, p e0148773 (2016)
Purpose Bardet-Biedl syndrome is a complex ciliopathy that usually manifests with some form of retinal degeneration, amongst other ciliary-related deficiencies. One of the genetic causes of this syndrome results from a defect in Bardet-Biedl Syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68fd4a4299487c5afb1dd58fdfa271e
https://doi.org/10.1371/journal.pone.0148773
https://doi.org/10.1371/journal.pone.0148773
Autor:
Paul A. Hargrave, Donald R. Dugger, Ann H. Milam, Anatol Arendt, Krzysztof Palczewski, W. C. Smith
Publikováno v:
Journal of Biological Chemistry. 269:15407-15410
Inactivation of photolyzed rhodopsin requires phosphorylation of the receptor and binding of the 48-kDa regulatory protein arrestin. We recently isolated a novel form of arrestin, termed p44, that is truncated at the COOH terminus (Palczewski, K., Bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06769f11546b583d0edb54497b4284b7
https://doi.org/10.1016/s0021-9258(17)40691-0
https://doi.org/10.1016/s0021-9258(17)40691-0
Autor:
Susan Bolch, W. Clay Smith, Isi Esquenazi, Jian Li, Del Benzenhafer, Anatol Arendt, J. Hugh McDowell, Donald R. Dugger
Rod and cone photoreceptors are highly specialized cells in the mammalian retina that capture photons and transduce light energy into a change in membrane potential that is ultimately relayed to the visual cortex. Photons are absorbed in these photor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a07a61cf60c9fb3ca2e77b5342ecf7
https://europepmc.org/articles/PMC3101666/
https://europepmc.org/articles/PMC3101666/
Autor:
A. Legg, R. Gonzalez, E. Garcia-Rivera, Karen E. Kempler, Megan L. Porter, Donald R. Dugger, Barbara-Anne Battelle, C. Katti
Publikováno v:
The Journal of experimental biology. 213(Pt 15)
SUMMARY A long-standing concept in vision science has held that a single photoreceptor expresses a single type of opsin, the protein component of visual pigment. However, the number of examples in the literature of photoreceptors from vertebrates and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e5f279d503ffb930c0ecb59b5c4427
https://pubmed.ncbi.nlm.nih.gov/20639420
https://pubmed.ncbi.nlm.nih.gov/20639420
Autor:
W. Clay Smith, Donald R. Dugger, Jim Peterson, Beatrice M. Tam, J. Hugh McDowell, Orson L. Moritz, Paul A. Hargrave, Charles L. Shelamer, David S. Papermaster
Publikováno v:
Experimental eye research. 76(5)
Subcellular translocation of phototransduction proteins in response to light has previously been detected by immunocytochemistry. This movement is consistent with the hypothesis that migration is part of a basic cellular mechanism regulating photorec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1ca1b7d42e012856785ee0bc20a84b
https://pubmed.ncbi.nlm.nih.gov/12697419
https://pubmed.ncbi.nlm.nih.gov/12697419