Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Donald R. Bobbitt"'
Publikováno v:
Microchemical Journal. 76:105-112
The development of new approaches for assessing enantiomeric purity is an area of critical need in the pharmaceutical and biotechnological industries. Recent work has shown that two enantiomers, although virtually identical physically, may exhibit wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f482d9fbe4a71fbb4f08f4ddcc83af7f
https://doi.org/10.1016/j.microc.2003.10.006
https://doi.org/10.1016/j.microc.2003.10.006
Real-Time Assessment of Enantiomeric Purity Via a Polarimetric/Absorption Detector Response Function
Publikováno v:
Enantiomer: A Journal of Sterochemistry. 7:41-47
The development of methodology appropriate for the rapid and precise assessment of enantiomeric purity is a critical need in the life sciences with impact in a number of areas including biomedical research, biotechnology, and pharmaceutical science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9aa66e81ba6638972b434c8aad8aba
https://doi.org/10.1080/10242430210702
https://doi.org/10.1080/10242430210702
Autor:
Romeo D. Lodevico, Rekha D. Shah, Thomas J. Edkins, Hewva Saranadasa, Donald R. Bobbitt, Peter C. Meier
Publikováno v:
Enantiomer: A Journal of Sterochemistry. 7:11-22
This report compares laser-based polarimetric and UV data for quantitating incompletely resolved enantiomers by HPLC. Using L- and D-phenylalanine as a working model, response data is shown across the entire detection region while emphasizing the reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d44a20fdf02489877fde9face46ba88
https://doi.org/10.1080/10242430210703
https://doi.org/10.1080/10242430210703
Publikováno v:
Analytica Chimica Acta. 441:231-241
The properties of four ruthenium complexes and their efficiency as probes for chemiluminescent (CL) detection were evaluated, and a protocol for CL detection of a protein labeled with a tertiary amine was proposed. Of the four ruthenium complexes stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87b44f6ee36a9fd0e8da668e07c7c306
https://doi.org/10.1016/s0003-2670(01)01081-9
https://doi.org/10.1016/s0003-2670(01)01081-9
Autor:
Donald R. Bobbitt, Darrell R Fry
Publikováno v:
Microchemical Journal. 69:25-33
There exist a large number of immobilization strategies useful for preparing optical fiber (OF) sensors; one unique approach has been termed dynamic modification. Dynamic modification borrows techniques from reverse-phase high performance chromatogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b79e8709b76e3bc6a36537d1b754f4ad
https://doi.org/10.1016/s0026-265x(00)00191-0
https://doi.org/10.1016/s0026-265x(00)00191-0
Autor:
Donald R. Bobbitt, Sean W. Linder
Publikováno v:
TrAC Trends in Analytical Chemistry. 20:111-123
The unique response characteristics of optical activity detectors make them an important adjunct to high performance liquid chromatography (HPLC) for the analysis of biologically active molecules. The recent commercial introduction of turn-key, circu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7159215d1cce2d84c11e61f3b8f5bd23
https://doi.org/10.1016/s0165-9936(00)00083-2
https://doi.org/10.1016/s0165-9936(00)00083-2
Publikováno v:
Microchemical Journal. 65:189-195
Ru(bpy)33+-based chemiluminescence detection of underivatized amino acids was coupled to capillary electrophoresis and evaluated as a separation and detection methodology for the compositional analysis of peptides and proteins. Two tripeptides were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88c892bef3b4cd569e227613f68c402
https://doi.org/10.1016/s0026-265x(00)00052-7
https://doi.org/10.1016/s0026-265x(00)00052-7
Autor:
Xin Wang, Donald R. Bobbitt
Publikováno v:
Analytica Chimica Acta. 383:213-220
A significant number of different chemical functional groups can be sensitively detected via their chemiluminescent reaction with Ru(bpy)33+, thus suggesting that this detection strategy may have widespread application in a variety of important areas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1787993924f477f8908af606e212bce
https://doi.org/10.1016/s0003-2670(98)00811-3
https://doi.org/10.1016/s0003-2670(98)00811-3
Publikováno v:
Chirality. 11:187-194
This paper addresses direct HPLC detection of amino acids, di and tripeptides via laser-based polarimetry. Mass detection limits typically range from 0.5 to 50 μg injected on-column, corresponding to concentration levels from 0.1 to 1 mg/ml. These l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::331b90a3304c3d87d235e22aa9abfd67
https://doi.org/10.1002/(sici)1520-636x(1999)11:3<187::aid-chir3>3.0.co
https://doi.org/10.1002/(sici)1520-636x(1999)11:3<187::aid-chir3>3.0.co