Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Donald R. Bertolini"'
Autor:
Joanna Debear, William Lathrop, Donald R. Bertolini, Paul P. Tamburini, Qing Qing Qiu, Yu Dong
Publikováno v:
Journal of Bone and Mineral Research. 13:1539-1546
Interconversion of estrogens by osteoblasts may play a role in regulating bone mass. As a first step toward exploring this possibility, we investigated the expression and activity of 17beta-hydroxysteroid dehydrogenases (17beta-HSDs) in cultured huma
Publikováno v:
Journal of Bone and Mineral Research. 18:1605-1611
To investigate the role of leptin in bone formation, the skeleton of the obese female leptin receptor-deficient Zucker rat was examined using pQCT, μCT, and histomorphometry. A trend toward decreasing structural and bone formation parameters in thes
Publikováno v:
Cytokine. 6:368-375
Reports from several laboratories have suggested that interleukin 6 (IL-6) may play a role in the process of bone resorption. We have extended these studies by examining the role of IL-6 in fetal rat long bone (FRLB) resorption stimulated by a variet
Publikováno v:
Cytokine. 5:463-468
The precise mechanisms responsible for increased calcium levels in patients with cancer are not fully understood. In a recent study, the participation of interleukin (IL)-6 as an important mediator of key parameters of cancer cachexia in the colon-26
Autor:
Qingqing Qiu, William Lathrop, John Cini, Daniel Weaver, David Chen, Donald R. Bertolini, Yu Dong
Publikováno v:
Biochemical and biophysical research communications. 251(3)
We report molecular cloning and initial functional characterization of a novel member of the low density lipoprotein receptor (LDLR) gene family. The cDNA was isolated from a human osteoblast cDNA library and encoded a 1,615 amino acids protein desig
Publisher Summary This chapter discusses the therapeutic potential of integrin antagonists. As the physiological importance of integrins becomes better defined so do strategies to perturb their function for therapeutic benefit. There is currently gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2812416dd339b37c71288ca88dc7e02
https://doi.org/10.1016/b978-0-08-091729-0.50014-0
https://doi.org/10.1016/b978-0-08-091729-0.50014-0
Autor:
Donald R. Bertolini, K. B. Tan
Publikováno v:
Cellular Adhesion ISBN: 9781461360506
Adhesion molecule involvement in bone remodeling is a relatively new area of research for bone biology. In the last 4 years there has been a considerable amount of data reported for adhesion molecules on bone cells, but this information is limited co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::098e3d95e0d724b5950f33413058237f
https://doi.org/10.1007/978-1-4615-2466-3_7
https://doi.org/10.1007/978-1-4615-2466-3_7
Autor:
JOHN ASHKENAS, DONALD R. BERTOLINI, MINA J. BISSELL, KEITH BURRIDGE, GINETTA COLLO, HELEN M. COOPER, CAROLINE H. DAMSKY, DOUGLAS W. DESIMONE, MARIANO J. ELICES, GUIDO GAIETTA, MARK D. HENS, MARKETTA HORMIA, THOMAS J. KUNICKI, THOMAS LALLIER, ANDREW J. NICHOLS, VITO QUARANTA, CARLA ROZZO, ZAVERIO M. RUGGERI, JAMES M. SAMANEN, MARTIN A. SCHWARTZ, KEIKO O. SIMON, JEFFREY W. SMITH, JEFFREY M. STADEL, LISA STARR, RICHARD N. TAMURA, ZENA WERB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f31243ef4a92cb6467e9cc0bb084172d
https://doi.org/10.1016/b978-0-08-091729-0.50004-8
https://doi.org/10.1016/b978-0-08-091729-0.50004-8
Autor:
Gideon Strassmann, Donald R. Bertolini
Publikováno v:
Cytokine. 3(5)
In this study, the ability of recombinant human macrophage (M) and murine granulocyte-macrophage macrophage (GM) colony stimulating factor (CSF) to affect both basal and stimulated bone resorption in fetal rat long-bone organ cultures was assessed. I
Publikováno v:
Differentiation. 21:79-85
Sea urchin embryos can be dissociated into a suspension of single cells that reconstitute embryo-like structures. When reconstitution is conducted in stationary cultures the first step is attachment of the cells to the culture plate, which requires c