Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Donald P. Island"'
Autor:
Rebecca L. Chan, Philip G. Hoffman, Spyros N. Pavlou, Clinton A. Nerenberg, Gail Wakefield, Mary Ellen LePage, William J. Kovacs, Donald P. Island
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 64:931-936
LHRH antagonists compete with endogenous LHRH for binding to receptors on pituitary gonadotrophs and thereby inhibit gonadal function by suppressing gonadotropin secretion. We studied the effects of a recently developed LHRH antagonist on the pituita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59be87b33da85b45fb9998a79cad0fc7
https://doi.org/10.1210/jcem-64-5-931
https://doi.org/10.1210/jcem-64-5-931
Autor:
G. Stephen Decherney, David N. Orth, C. Rowan Debold, Themis C. Kamilaris, Richard V. Jackson, William R. Sheldon, Donald P. Island
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 68:431-437
We studied 1) the nature of the plasma ACTH response to ovine CRH (oCRH) in the absence of normal glucocorticoid negative feedback inhibition and 2) the cause of the diminished circadian peak in plasma ACTH in normal men the morning after 3-30 microg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb620a1bf879601cf7cb67b00dac7599
https://doi.org/10.1210/jcem-68-2-431
https://doi.org/10.1210/jcem-68-2-431
Publikováno v:
The Journal of Pediatrics. 101:236-239
analysis may bias the sample toward higher mortality by including deceased siblings and because of failure to identify the very mild cases. In addition, the sample may have been biased toward lower mortality by omission of those severely affected pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d071fcdd73799fddfe447c999cc14a37
https://doi.org/10.1016/s0022-3476(82)80131-5
https://doi.org/10.1016/s0022-3476(82)80131-5
Autor:
G. Stephen Decherney, Themis C. Kamilaris, C. Rowan Debold, William R. Sheldon, David N. Orth, Donald P. Island, Richard V. Jackson
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 64:1211-1218
The factors that mediate the hypothalamic-pituitary response to hypoglycemia in man are unknown. To investigate the role of CRH in the plasma ACTH response to hypoglycemia, two different doses of ovine CRH (oCRH) were given to normal men during insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22a1942cfb6b4dad8c52333d71a47f5
https://doi.org/10.1210/jcem-64-6-1211
https://doi.org/10.1210/jcem-64-6-1211
Autor:
William J. Kovacs, Gail Wakefield, Wylie Vale, Donald P. Island, Spyros N. Pavlou, Jean Rivier, John W. Interlandi
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 64:1070-1074
The ability of prolonged administration of a LHRH antagonist, [Ac-delta 3Pro1,4F-D-Phe2,D-Trp3,6]LHRH (4F-antagonist), to suppress serum gonadotropin and testosterone levels was studied in normal men. The 4F-antagonist was given either as a continuou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7989bbe4a203b6add56c76ec558cff0
https://doi.org/10.1210/jcem-64-5-1070
https://doi.org/10.1210/jcem-64-5-1070
Publikováno v:
Steroids. 32:127-136
Adrenal glands obtained from patients undergoing therapeutic adrenalectomy were used to study the effects of angiotensin on human adrenal steroidogenesis. It was observed that angiotensin stimulated cortisol biosynthesis. Although this has been demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5eca592d77ab45e6ffdaf791385244d
https://doi.org/10.1016/0039-128x(78)90105-8
https://doi.org/10.1016/0039-128x(78)90105-8
Publikováno v:
Metabolism. 31:510-513
A clinically euthyroid 2-yr-old girl was found to have diffuse goiter that measured 3 X 5.5 cm with a prominent systolic bruit. Serum free T4 (3.4 ng/dl) and serum T3 (360 ng/dl) remained elevated for the next 10 months even though she remained clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d81bf9eadad8781e3696424e39d1f32
https://doi.org/10.1016/0026-0495(82)90243-8
https://doi.org/10.1016/0026-0495(82)90243-8
Publikováno v:
Computer Methods and Programs in Biomedicine. 27:241-248
ENDO-LAB is an IBM PC-based system which performs calculations and record-keeping for the Vanderbilt University Medical Center Endocrinology Laboratory. It manages maintenance and quality control, and prints reports for regulatory agencies. The syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4422fa1134d81434cab86183377ceaf2
https://doi.org/10.1016/0169-2607(88)90088-0
https://doi.org/10.1016/0169-2607(88)90088-0
Autor:
G. Stephen Decherney, Richard V. Jackson, Donald P. Island, David N. Orth, C. Rowan Debold, William R. Sheldon
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 61:273-279
To determine whether the plasma immunoreactive ACTH (IR-ACTH) and IR-cortisol responses to ovine corticotropin-releasing hormone (oCRH) depend on the time of day, we administered 1 microgram/kg BW synthetic oCRH as an iv bolus dose to five normal men
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5d9de485cf86968da10ef71c16d478
https://doi.org/10.1210/jcem-61-2-273
https://doi.org/10.1210/jcem-61-2-273
Autor:
Michael O. Thorner, Richard V. Jackson, C. Rowan Debold, William R. Sheldon, William S. Evans, Donald P. Island, G. Stephen Decherney, David N. Orth
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 60:623-630
Normal subjects were studied to test the feasibility of a combined anterior pituitary function test using iv administration of four hypothalamic releasing hormones: ovine corticotropin-releasing hormone, human GH-releasing hormone, GnRH, and TRH. Ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ef5c7519d63bc36389ae047dd7f67c
https://doi.org/10.1210/jcem-60-4-623
https://doi.org/10.1210/jcem-60-4-623