Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Donald P Francis"'
Autor:
Peter B Gilbert, Jean-Louis Excler, Georgia D Tomaras, Lindsay N Carpp, Barton F Haynes, Hua-Xin Liao, David C Montefiori, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Jaranit Kaewkungwal, Gustavo H Kijak, Sodsai Tovanabutra, Donald P Francis, Carter Lee, Faruk Sinangil, Phillip W Berman, Nakorn Premsri, Prayura Kunasol, Robert J O'Connell, Nelson L Michael, Merlin L Robb, Rhoda Morrow, Lawrence Corey, Jerome H Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176428 (2017)
BACKGROUND:In the HIV-1 vaccine trial RV144, ALVAC-HIV prime with an AIDSVAX® B/E boost reduced HIV-1 acquisition by 31% at 42 months post first vaccination. The bivalent AIDSVAX® B/E vaccine contains two gp120 envelope glycoproteins, one from the
Externí odkaz:
https://doaj.org/article/749ab0ed603a4682a6678cef9d673819
Autor:
Richard Mahoney, Liliana Chocarro, James Southern, Donald P Francis, John Vose, Harold Margolis
Publikováno v:
PLoS Medicine, Vol 8, Iss 2, p e1000418 (2011)
Externí odkaz:
https://doaj.org/article/c032232074c94830b8c66eb26d3fbdc8
Autor:
Punnee Pitisuttithum, Supachai Rerks-Ngarm, Valai Bussaratid, Jittima Dhitavat, Wirach Maekanantawat, Swangjai Pungpak, Pravan Suntharasamai, Sirivan Vanijanonta, Sorachai Nitayapan, Jaranit Kaewkungwal, Michael Benenson, Patricia Morgan, Robert J O'Connell, Jeffrey Berenberg, Sanjay Gurunathan, Donald P Francis, Robert Paris, Joseph Chiu, Donald Stablein, Nelson L Michael, Jean-Louis Excler, Merlin L Robb, Jerome H Kim
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27837 (2011)
A prime-boost vaccination regimen with ALVAC-HIV (vCP1521) administered intramuscularly at 0, 4, 12, and 24 weeks and gp120 AIDSVAX B/E at 12 and 24 weeks demonstrated modest efficacy of 31.2% for prevention of HIV acquisition in HIV-uninfected adult
Externí odkaz:
https://doaj.org/article/932fc5691218438b9c3e98883140fb14
Publikováno v:
Vaccine
One of the aims of the WHO Global Action Plan for Influenza Vaccines (GAP) was to transfer influenza vaccine production technology to interested manufacturers and governments in developing countries, to enable greater influenza vaccine manufacturing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11583e6b4740112132241269f95ee00
https://doi.org/10.1016/j.vaccine.2016.07.047
https://doi.org/10.1016/j.vaccine.2016.07.047
Publikováno v:
Vaccine. 32:5259-5265
Hallmarks in the remarkable evolution of vaccines and their application include the eradication of smallpox, the development and delivery of the early childhood vaccines and the emergence of recombinant vaccines initiated by the hepatitis B vaccine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb236e15f6d204f4ce16a690b4bcc64
https://doi.org/10.1016/j.vaccine.2014.07.069
https://doi.org/10.1016/j.vaccine.2014.07.069
Autor:
Merlin L. Robb, Jean-Louis Excler, Jerome H. Kim, James Tartaglia, Mark de Souza, Chitraporn Karnasuta, Sorachai Nitayaphan, Nelson L. Michael, Siriwat Akapirat, Sirinan Madnote, Supachai Rerks-Ngarm, Jaranit Kaewkungwal, Faruk Sinangil, Robert J. O'Connell, Nicos Karasavvas, Punnee Pitisuttithum, Surawach Rittiroongrad, Donald P. Francis, Hathairat Savadsuk, Jiraporn Puangkaew
Publikováno v:
AIDS Research and Human Retroviruses
The RV144 prime-boost regimen demonstrated efficacy against HIV acquisition while VAX003 and VAX004 did not. Although these trials differed by risk groups, immunization regimens, and immunogens, antibody responses may have contributed to the differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef094c5c02f8b578c1f18301181c733
https://pubmed.ncbi.nlm.nih.gov/28006952
https://pubmed.ncbi.nlm.nih.gov/28006952
Autor:
Laura L. Sutherland, Guido Ferrari, Giovanna Hernandez, Jamie Pritchett, Norman L. Letvin, Supachai Rerks-Ngarm, Faruk Sinangil, Ashley A. Allen, Nelson L. Michael, Robert Parks, Erika Dunford, Donald P. Francis, Mattia Bonsignori, Georgia D. Tomaras, John F. Whitesides, Punnee Pitisuttithum, David Easterhoff, Christina Stolarchuk, R. Whitney Edwards, M. Anthony Moody, Krissey E. Lloyd, Thaddeus C. Gurley, Hua-Xin Liao, Barton F. Haynes, Carter Lee, Andrew Foulger, Tarra Von Holle, Sorachai Nitayaphan, Dawn J. Marshall, Jaranit Kaewkungwal, Sampa Santra, Ruijun Zhang, Kan Luo, Shi-Mao Xia, Kevin Wiehe, Richard M. Scearce, Sabrina Arora, Jerome H. Kim, Sheetal Sawant, David C. Montefiori, Cindy M. Bowman, Lawrence C. Armand, S. Munir Alam, James Tartaglia, Nathan Vandergrift, Amy Wang, Nicole L. Yates, Jessica N. Peel, Justin Pollara
Publikováno v:
JCI Insight. 1
The ALVAC prime/ALVAC + AIDSVAX B/E boost RV144 vaccine trial induced an estimated 31% efficacy in a low-risk cohort where HIV‑1 exposures were likely at mucosal surfaces. An immune correlates study demonstrated that antibodies targeting the V2 reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fcdf56204b6eea0a101540ed1185236
https://doi.org/10.1172/jci.insight.88522
https://doi.org/10.1172/jci.insight.88522
Autor:
Todd J. Suscovich, Lindsey R. Baden, Maria Pau, Dagna Laufer, Hanneke Schuitemaker, Bruce D. Walker, Hendrik Streeck, Patricia E. Fast, Dan H. Barouch, Donald P. Francis, Kendall Dionne, Alison E. Mahan, Amy W. Chung, Galit Alter, Madeleine F. Jennewein, Jacquelynne Tedesco
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 6, p e1005694 (2016)
PLoS Pathogens, Vol 12, Iss 6, p e1005694 (2016)
Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2f8d571b0cac603d10cb8e41e2d7af
http://europepmc.org/articles/PMC4890747
http://europepmc.org/articles/PMC4890747
Autor:
Todd J. Suscovich, Hanneke Schuitemaker, Jacquelynne Tedesco, Amy W. Chung, Dagna Laufer, Lindsey R. Baden, Maria Pau, Madeleine F. Jennewein, Dan H. Barouch, Hendrik Streeck, Kendall Dionne, Patricia E. Fast, Bruce D. Walker, Alison E. Mahan, Galit Alter, Donald P. Francis
Publikováno v:
PLoS pathogens, 12(3). Public Library of Science
PLoS Pathogens, Vol 12, Iss 3, p e1005456 (2016)
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 3, p e1005456 (2016)
PLoS Pathogens
Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b4d61b5912f7ce6664f95cb29f9568
https://pure.amc.nl/en/publications/antigenspecific-antibody-glycosylation-is-regulated-via-vaccination(3004b852-e564-4cf2-9447-0386d57dcc59).html
https://pure.amc.nl/en/publications/antigenspecific-antibody-glycosylation-is-regulated-via-vaccination(3004b852-e564-4cf2-9447-0386d57dcc59).html
Autor:
Stephen S. Whitehead, Alexander Roberto Precioso, Isaias Raw, P. Whitehead, P. Watler, Richard T. Mahoney, N. M. Frazatti-Gallina, Donald P. Francis
Publikováno v:
Vaccine. 30:4892-4896
Background A vaccine to prevent dengue disease is urgently needed. Fortunately, a few tetravalent candidate vaccines are in the later stages of development and show promise. But, if the cost of these candidates is too high, their beneficial potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be0e29732455caa472de9b773cbbef3
https://doi.org/10.1016/j.vaccine.2012.02.064
https://doi.org/10.1016/j.vaccine.2012.02.064