Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Donald M. Wieland"'
Publikováno v:
Principles of Radiopharmacology ISBN: 9780429288760
Principles of Radiopharmacology
Principles of Radiopharmacology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6d434b20ed1bff449ea5403936d29b
https://doi.org/10.1201/9780429288760-4
https://doi.org/10.1201/9780429288760-4
Autor:
Donald M. Wieland
Publikováno v:
Receptor-Binding Radiotracers ISBN: 9780429290794
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::230987495fe09198eede8ce6b7281651
https://doi.org/10.1201/9780429290794-9
https://doi.org/10.1201/9780429290794-9
Autor:
Otto Muzik, Donald M. Wieland, Stephan G. Nekolla, Ngoc Nguyen, Pulak K. Chakraborty, Sibylle Ziegler, Markus Schwaiger, Götz Münch
Publikováno v:
Circulation. 101:516-523
Background —The goal of the present study was to directly compare the new radiopharmaceutical agent [ 11 C]epinephrine (EPI) with [ 11 C]hydroxyephedrine (HED) through the use of PET. Methods and Results —Seven healthy volunteers and 10 patients
In 1906, Michael T. Sweet first developed the chromatographic method by using an adsorbant to separate pigments. Since that time, the technological advances in TLC and HPLC have brought about new definitions of purity in parallel with the advances. R
Publikováno v:
Metabolism. 48:92-101
Cardiovascular denervation complicating diabetes has been implicated in sudden cardiac death potentially by altering myocardial electrical stability and impairing myocardial blood flow. Scintigraphic evaluation of cardiac sympathetic integrity has fr
Autor:
G. Keith Mulholland, James E. Carey, Phillip S. Sherman, David E. Kuhl, Kirk A. Frey, Michael R. Kilbourn, Donald M. Wieland
Publikováno v:
Synapse. 30:263-274
Loss of cholinergic transmission in the cortex and hippocampus is a characteristic feature of Alzheimer's disease, and visualization of functional cholinergic synapses in the brain with PET could be a useful method for studying this degenerative cond
Autor:
Tracy Sandford, David M. Raffel, James R. Corbett, Marcus Schwaiger, Firat Dayanikli, Eva L. Feldman, Donald M. Wieland, Kevin C. Allman, Martin J. Stevens
Publikováno v:
Journal of the American College of Cardiology. 31:1575-1584
Objectives. This study sought to evaluate whether regional sympathetic myocardial denervation in diabetes is associated with abnormal myocardial blood flow under rest and adenosine-stimulated conditions.Background. Diabetic autonomic neuropathy (DAN)
Autor:
Donald M. Wieland, Yong Woon Jung, Renato B. Del Rosario, Pulak K. Chakraborty, John M. Caraher
Publikováno v:
Nuclear Medicine and Biology. 23:611-616
The in vivo behavior of (-)-[11C]phenylephrine (PHEN) is compared with the structurally similar but monoamine oxidase (MAO)-resistant analog (-)-[11C]-m-hydroxyephedrine (HED), which is an established heart neuronal marker. The chiral synthesis of PH
Autor:
Donald M. Wieland, David L. Gildersleeve, Jon W. Johnson, Marcian E. Van Dort, Phillip S. Sherman
Publikováno v:
Nuclear Medicine and Biology. 23:23-28
An iodinated analog of PK11195, 1-(2-chlorophenyl)- N -methyl- N -(1-methylpropyl)isoquinoline-3-carboxamide, a specific antagonist of the peripheral-type benzodiazepine receptor (ω 3 ), has been synthesized in three steps with an overall chemical y
Autor:
Yong-Woon Jung, David M. Raffel, Renato B. Del Rosario, and David L. Gildersleeve, Donald M. Wieland, G. Keith Mulholland, Phillip S. Sherman, David E. Kuhl, Marcian E. Van Dort, Kirk A. Frey
Publikováno v:
Journal of Medicinal Chemistry. 39:3331-3342
Alzheimer's disease is characterized by progressive cerebral cholinergic neuronal degeneration. Radiotracer analogs of benzovesamicol, which bind with high affinity to the vesamicol receptor located on the uptake transporter of acetylcholine storage