Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Donald M. Lyster"'
Autor:
Michael T. Janusz, A. Karim Qayumi, Elizabeth J. E. Feeley, A. Poostizadeh, W.R. Eric Jamieson, Maryam Nikbakht-Sangari, Katerina Dorovini-Zis, Donald M. Lyster
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 107:1203-1209
Fourteen domestic swine were divided into two groups. Group A ( n = 7) was the control group, in which no pharmacologic intervention was applied. In group B ( n = 7), the ischemic-reperfused spinal cord was treated with the combination of allopurinol
Autor:
Can Vo, D. Scott Edwards, Gordon A. Webb, Michael J. Poirier, Donald M. Lyster, Zaihui Zhang, Shuang Liu, Chris Orvig
Publikováno v:
Nuclear Medicine and Biology. 20:857-863
A series of monocationic complexes of N-substituted-3-hydroxy-2-methyl-4-pyridinones labeled with technetium(IV)-99m have been evaluated in vivo as potential radiopharmaceuticals. The pyridinones have different substituents at the ring nitrogen atom:
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 33:327-344
The ortho-, meta- and para-[123I]-2-deoxy-2-N-(iodobenzoyl)-D-glucosamine (BGA) derivatives were investigated to determine the effect of iodine position and lipophilicity on tissue distribution. There was no correlation between tissue uptake and lipo
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 104:256-261
The efficacy of pharmacologic agents for prevention and control of oxygen-derived free radical damage in ischemia-reperfusion injury of the spinal cord was assessed in a swine model of thoracic and thoracoabdominal aortic crossclamping. Animals were
Autor:
Hayes Dougan, Donald M. Lyster
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes. 43:699-703
While developing organomercury precursor routes for para [123I]IPPA, we discovered abundant meta IPPA ethyl ester following mercuration in trifluoroacetic acid (TFA) (20°C) and subsequent iodination. 1H-NMR and HPLC were employed for analysis and id
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 19:327-335
A series of highly lipophilic complexes of 1-aryl-3-hydroxy-2-methyl-4-pyridinones with gallium(III)-67 has been evaluated in vitro and in vivo as potential radiopharmaceuticals. The pyridinones have different substituents at the para-position of the
Autor:
T. Rihela, Marck P. J. Hudon, W. R. E. Jamieson, P. Cohen, T. Lutz, Hayes Dougan, Donald M. Lyster
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 29:535-545
The ortho, meta and para iodinated series of 2-deoxy-2-O-(iodobenzyl)glucose (IBG) were prepared by addition of the desired iodobenzyl bromide with 3,4,6-tri-O-acetyl-piperidine-N-D-glucose. Subsequent exchange labelling with [123I]NaI enabled their
Autor:
K. D. Gillespie, Donald M. Lyster, Briege McConville, Marck P. J. Hudon, A. K. Qayumi, M. Schulzer, W. R. E. Jamieson, L. J. Rosado
Publikováno v:
Journal of Investigative Surgery. 4:93-102
The present study compares simple hypothermic storage and hypothermic perfusion in a swine model of heart transplantation using metabolic and functional assessments. In both groups the hearts were initially protected with iso-osmolar potassium Tyers'
Autor:
Terri L. Rihela, Donald M. Lyster, David J. Clevette, William O. Nelson, Gordon A. Webb, Chris Orvig
Publikováno v:
Inorganic Chemistry. 29:667-672
A series of complexes of several 3-hydroxy-2-methyl-4-pyridinones with gallium(III) and indium(III) have been characterized by potentiometric (glass electrode) titration. The effective formation constants of the various ligands for Ga 3+ at physiolog
Autor:
Alan R. Stafford, Jeffrey I. Weitz, Petr Klement, John B. Hobbs, Hayes Dougan, Donald M. Lyster, Kris D Gillespie
Publikováno v:
Nuclear medicine and biology. 30(1)
Two DNA aptamers directed against two separate exosites on human alpha-thrombin were evaluated for thrombus-imaging potential. Aptamer ODN 1 is directed to the thrombin substrate binding site (exosite 1). Our finding that ODN 1 competes with fibrin f