Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Donald M. Lyall"'
Autor:
Mengrong Zhang, Joey Ward, Rona J. Strawbridge, Carlos Celis-Morales, Jill P. Pell, Donald M. Lyall, Frederick K. Ho
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Obesity and central obesity are multifactorial conditions with genetic and non-genetic (lifestyle and environmental) contributions. There is incomplete understanding of whether lifestyle modifies the translation from respective ge
Externí odkaz:
https://doaj.org/article/0618265a53c6499c8c30c6156b7beff3
Autor:
Joey Ward, Laura M. Lyall, Breda Cullen, Rona J. Strawbridge, Xingxing Zhu, Ioana Stanciu, Alisha Aman, Claire L. Niedzwiedz, Jana Anderson, Mark E. S. Bailey, Donald M. Lyall, Jill P. Pell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Happiness is a fundamental human affective trait, but its biological basis is not well understood. Using a novel approach, we construct LDpred-inf polygenic scores of a general happiness measure in 2 cohorts: the Adolescent Brain Cognitive D
Externí odkaz:
https://doaj.org/article/80fe9bf8ebab4344ac6435ca01993e32
Autor:
Jodi K. Watt, David Alexander Dickie, Frederick K. Ho, Donald M. Lyall, Jesse Dawson, Terence J. Quinn
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100214- (2024)
Background: Brain Health Index (BHI) assimilates various MRI sequences, giving a quantitative measure of brain health. To date, BHI validation has been cross-sectional and limited to selected populations. Further large-scale validation and assessment
Externí odkaz:
https://doaj.org/article/5e342f4059124087afd3d390fc0d6a8d
Autor:
Jodi K. Watt, David Alexander Dickie, Donald M. Lyall, Joey Ward, Frederick K. Ho, Jesse Dawson, Terence J. Quinn
Publikováno v:
Neuroimage: Reports, Vol 3, Iss 3, Pp 100176- (2023)
Background: The Brain Health Index (BHI) is an automated approach to quantifying brain integrity, combining different types of structural magnetic resonance imaging (MRI). Normative values derived from generally healthy individuals provide a vital ba
Externí odkaz:
https://doaj.org/article/bb8ac90be7524ce195b9ac17d4e03e37
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract While previous rheumatoid arthritis (RA) studies have focussed on cardiometabolic and lifestyle factors, less research has focussed on psychological variables including mood and cognitive health, and sleep. Cross-sectional analyses tested fo
Externí odkaz:
https://doaj.org/article/67ebf15a22bc48708cd1fc7c741f8799
Autor:
Irene Esteban‐Cornejo, Frederick K. Ho, Fanny Petermann‐Rocha, Donald M. Lyall, David Martinez‐Gomez, Verónica Cabanas‐Sánchez, Francisco B. Ortega, Charles H. Hillman, Jason M.R. Gill, Terence J. Quinn, Naveed Sattar, Jill P. Pell, Stuart R. Gray, Carlos Celis‐Morales
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1514-1525 (2022)
Abstract Background This study aimed to investigate the associations of grip strength with incidence and mortality from dementia and whether these associations differ by sociodemographic and lifestyle factors. Methods A total of 466 788 participants
Externí odkaz:
https://doaj.org/article/158bab48fbb74105bc436c46b75db791
Autor:
Fanny Petermann-Rocha, Donald M. Lyall, Stuart R. Gray, Jason M. R. Gill, Naveed Sattar, Paul Welsh, Terence J. Quinn, William Stewart, Jill P. Pell, Frederick K. Ho, Carlos Celis-Morales
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Previous cohort studies have investigated the relationship between self-reported physical activity (PA) and dementia. Evidence from objective device-measured PA data is lacking. This study aimed to explore the association of devic
Externí odkaz:
https://doaj.org/article/4e6805a52e1e499289594d626514e55e
Autor:
Xingxing Zhu, Joey Ward, Breda Cullen, Donald M. Lyall, Rona J. Strawbridge, Laura M. Lyall, Daniel J. Smith
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Anhedonia is a core symptom of multiple psychiatric disorders and has been associated with alterations in brain structure. Genome-wide association studies suggest that anhedonia is heritable, with a polygenic architecture, but few studies ha
Externí odkaz:
https://doaj.org/article/9cc2fbfc954c4c5c94085397fdf1f3db
Autor:
Rona J. Strawbridge, Keira J. A. Johnston, Mark E. S. Bailey, Damiano Baldassarre, Breda Cullen, Per Eriksson, Ulf deFaire, Amy Ferguson, Bruna Gigante, Philippe Giral, Nicholas Graham, Anders Hamsten, Steve E. Humphries, Sudhir Kurl, Donald M. Lyall, Laura M. Lyall, Jill P. Pell, Matteo Pirro, Kai Savonen, Andries J. Smit, Elena Tremoli, Tomi-Pekka Tomainen, Fabrizio Veglia, Joey Ward, Bengt Sennblad, Daniel J. Smith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Understanding why individuals with severe mental illness (Schizophrenia, Bipolar Disorder and Major Depressive Disorder) have increased risk of cardiometabolic disease (including obesity, type 2 diabetes and cardiovascular disease), and iden
Externí odkaz:
https://doaj.org/article/7e59d46ec2fd4250ae99b8ac5242f619
Autor:
Jana J. Anderson, Stuart R. Gray, Paul Welsh, Daniel F. Mackay, Carlos A. Celis-Morales, Donald M. Lyall, John Forbes, Naveed Sattar, Jason M. R. Gill, Jill P. Pell
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Recent efforts to address the obesity epidemic have focused on sugar consumption, especially sugar-sweetened beverages. However, sugar takes many forms, is only one contributor to overall energy consumption and is correlated with
Externí odkaz:
https://doaj.org/article/67c506ca06c2459999d34b751ee5cf94