Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Donald M. Eicher"'
Autor:
Donald M. Eicher
Publikováno v:
Cellular Immunology. 223:133-142
IL-2 and IL-15 are cytokines involved in T cell activation and death. Their non-shared receptors, IL-2Ralpha and IL-15Ralpha, are important in the homeostasis of lymphocytes as evidenced by gene deletion studies. How these cytokine/receptor systems a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df94092e5fbc7739232aa82a33077084
https://doi.org/10.1016/s0008-8749(03)00168-0
https://doi.org/10.1016/s0008-8749(03)00168-0
Publikováno v:
Cytokine. 17:82-90
Interleukin (IL) 2 receptor subunit alpha (IL-2Rα) increases the affinity of the IL-2 receptor complex while hetero-association of IL-2Rβ and γ c chains initiates a proliferative signal. We show here that IL-2Rα is necessary for receptor clusteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480055e496ca473e99f9361e5ce1c1af
https://doi.org/10.1006/cyto.2001.0978
https://doi.org/10.1006/cyto.2001.0978
Autor:
Sagar Lonial, Donald M. Eicher, Antonio Palumbo, Bijay Nair, Heesun J. Rogers, Federica Cavallo, Sarah Waheed, Craig C. Hofmeister
Publikováno v:
Seminars in oncology. 41(1)
is present in 3%–4% of the general population, 3 progressing to multiple myeloma at ar ate of 1% per year. 4 Prognosis in patients with multiple myeloma depends on several variables, including age, performance status, renal function, disease stage,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f55f0ff87b62185df38916d9774de1
https://pubmed.ncbi.nlm.nih.gov/24565588
https://pubmed.ncbi.nlm.nih.gov/24565588
Autor:
Donald M. Eicher, Thomas A. Waldmann
Publikováno v:
The Journal of Immunology. 161:5430-5437
IL-2Rα augments IL-2 signaling. Although this is generally believed to occur only when the three known components of IL-2R are associated within a single cell membrane, we demonstrate here an intercellular interaction. Cocultivation of cells individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f6398fc977072882794b5ee0e3a7b76
https://doi.org/10.4049/jimmunol.161.10.5430
https://doi.org/10.4049/jimmunol.161.10.5430
Publikováno v:
Cellular Immunology. 140:295-303
The modulation of adhesion molecules on human large granular lymphocytes (LGL) by in-terleukin (IL)-2 was investigated both in vivo and in vitro . Intercellular adhesion molecule-1 (ICAM-1; CD54) expression increased on LGL of cancer patients receivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291098a05be3333fd6ff4acfe446fdbb
https://doi.org/10.1016/0008-8749(92)90197-w
https://doi.org/10.1016/0008-8749(92)90197-w
Publikováno v:
Cytokine. 17(2)
Interleukin (IL) 2 receptor subunit alpha (IL-2Ralpha) increases the affinity of the IL-2 receptor complex while hetero-association of IL-2Rbeta and gamma(c) chains initiates a proliferative signal. We show here that IL-2Ralpha is necessary for recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce429d65d99c7ba7f494bbc52f1fae3f
https://pubmed.ncbi.nlm.nih.gov/11886175
https://pubmed.ncbi.nlm.nih.gov/11886175
Autor:
Thomas A. Waldmann, Michael Derby, Donn M. Stewart, Thomas A. Fleisher, Lois E. Top, Gilian Wharfe, Barrie Hanchard, David L. Nelson, Ashish Jain, Virginia E. Maher, Jeffrey D. White, Cathryn C. Lee, Donald M. Eicher, Daniel Lucy, Peta-Gay Jackson-booth, Bert Herring, Margaret Marshall, Beverley Cranston
Publikováno v:
Leukemialymphoma. 40(3-4)
Adult T-cell leukemia/lymphoma (ATL) is frequently a very aggressive malignancy with a poor survival despite aggressive multiagent chemotherapy. The combination of the antiretroviral drug zidovudine (AZT) and interferon alpha (IFNalpha) has been repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c75ad921668ae417ee18ab2514c494a
https://pubmed.ncbi.nlm.nih.gov/11426550
https://pubmed.ncbi.nlm.nih.gov/11426550