Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Donald M. Brunette"'
Publikováno v:
Journal of Periodontal Research. 55:959-968
Tony Melcher, a highly influential and forward-thinking scientist and teacher, focussed on the origins, behaviour and regulation of cells in periodontal tissues. His recent death in April 2020, has motivated us to highlight his multi-level contributi
Publikováno v:
Journal of Dental Research. 99:1315-1317
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:2499-2509
Recognition of topographical features induces phenotypic changes in macrophages although the receptors and signaling pathways are not completely characterized. As integrin molecules in focal adhesions/podosomes are in intimate contact with topography
Autor:
Donald M. Brunette
Publikováno v:
Endodontic Topics. 34:8-29
It has long been assumed that science is self-correcting and that lack of reproducibility or even fraud will be uncovered in subsequent attempts to replicate observations or experiments. Recent studies have cast doubt on that assumption, which is a c
Autor:
Nicolas A. F. Jaeger, Haisle Moon, Christopher M. Overall, Clément V. M. Cremmel, Alina Kulpa, Reinhild Kappelhoff, J. Douglas Waterfield, Donald M. Brunette
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:2243-2254
Rough surface topographies on implants attract macrophages but the influence of topography on macrophage fusion to produce multinucleated giant cells (MGC) and foreign body giant cells (FBGC) is unclear. Two rough novel grooved substrata, G1 and G2,
Publikováno v:
Journal of Biomedical Materials Research Part A. :2679-2688
Monocyte-derived cells, including macrophages and foreign body giant cells, can determine the performance of implanted devices. Upon contact with biomaterials, macrophages can be activated into a classic inflammatory (M1) or wound-healing (M2) phenot
Publikováno v:
Journal of Biomedical Materials Research Part A. :2118-2128
Implant surface topography can modulate macrophage behavior during wound healing by the production of proinflammatory cytokines. This study investigated the activation of FAK, Src, and ERK1/2 signaling intermediates of the proinflammatory ERK1/2 path
Autor:
Haisle, Moon, Clément V M, Cremmel, Alina, Kulpa, Nicolas A F, Jaeger, Reinhild, Kappelhoff, Christopher M, Overall, J Douglas, Waterfield, Donald M, Brunette
Publikováno v:
Journal of biomedical materials research. Part A. 104(9)
Rough surface topographies on implants attract macrophages but the influence of topography on macrophage fusion to produce multinucleated giant cells (MGC) and foreign body giant cells (FBGC) is unclear. Two rough novel grooved substrata, G1 and G2,
Publikováno v:
Journal of Biomedical Materials Research Part A. :294-304
Microtopographic features affect diverse cell behaviors. Adult bone marrow progenitor cells (AMPCs) constitute a multipotent heterogeneous population. We hypothesized that microtopographies could direct AMPCs lineage-specific differentiation. AMPCs i
Publikováno v:
Journal of Biomedical Materials Research Part A. :149-157
A desirable attribute of implants penetrating epithelium is the inhibition of downward epithelial migration. Simple grooved topographies can inhibit this migration either directly or indirectly by promoting connective tissue attachment, but few studi