Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Donald M Bryant"'
Autor:
Konstantinos Sousounis, Donald M Bryant, Jose Martinez Fernandez, Samuel S Eddy, Stephanie L Tsai, Gregory C Gundberg, Jihee Han, Katharine Courtemanche, Michael Levin, Jessica L Whited
Publikováno v:
eLife, Vol 9 (2020)
How salamanders accomplish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerative potential remains elusive. Here we found an innate DNA damage response mechanism that is evident during blastema proliferation (e
Externí odkaz:
https://doaj.org/article/e92586a6cf15483d87539483428919e5
Autor:
Nicholas D. Leigh, Garrett S. Dunlap, Kimberly Johnson, Rachelle Mariano, Rachel Oshiro, Alan Y. Wong, Donald M. Bryant, Bess M. Miller, Alex Ratner, Andy Chen, William W. Ye, Brian J. Haas, Jessica L. Whited
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Limb regeneration requires a blastema with progenitor cells, immune cells, and an overlying wound epidermis, but molecular identities of these populations are unclear. Here, the authors use single-cell RNA-sequencing to identify transcriptionally dis
Externí odkaz:
https://doaj.org/article/4ed4afd9e0f24ba282c5975966235607
Autor:
Rachel Oshiro, Donald M. Bryant, Nicholas D. Leigh, Jessica L. Whited, Garrett S. Dunlap, A. W. Chen, Alex Ratner, Brian J. Haas, Rachelle Mariano, William W. Ye, Alan Y. Wong, Bess M. Miller, Kimberly Johnson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
Regeneration of complex multi-tissue structures, such as limbs, requires the coordinated effort of multiple cell types. In axolotl limb regeneration, the wound epidermis and blastema have been extensively studied via histology, grafting, and bulk-tis
Autor:
Katharine Courtemanche, Jessica L. Whited, Jihee Han, Jose Martinez Fernandez, Donald M. Bryant, Michael Levin, Stephanie L. Tsai, Samuel S Eddy, Konstantinos Sousounis, Gregory C Gundberg
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
How salamanders accomplish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerative potential remains elusive. Here we found an innate DNA damage response mechanism that is evident during blastema proliferation (e
Autor:
Samuel S Eddy, Jessica L. Whited, Donald M. Bryant, Gregory C Gundberg, Jose Martinez Fernandez, Katharine Courtemanche, Konstantinos Sousounis, Michael Levin, Jihee Han, Stephanie L. Tsai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6b647371b2c02531c6feb23c3fba81
https://doi.org/10.7554/elife.51217.sa2
https://doi.org/10.7554/elife.51217.sa2
Autor:
Jessica L. Whited, Konstantinos Sousounis, Anna R. Guzikowski, Michael Levin, Neng Thao, Donald M. Bryant, Sevara Bryant, Johanna E. Farkas, James R. Monaghan
Publikováno v:
Developmental Biology. 424:1-9
Matching appendage size to body size is fundamental to animal function. Generating an appropriately-sized appendage is a robust process executed during development which is also critical for regeneration. When challenged, larger animals are programme
Autor:
Nicholas Leigh, Garrett Dunlap, Kimberly Johnson, Rachelle Mariano, Rachel Oshiro, Alan Y. Wong, Donald M. Bryant, Bess Miller, Jessica L. Whited
This protocol provides details on tissue harvest and fixation, RNA probe generation, and RNA in situ hybridization for use in sectioned axolotl tissue.This protocol was modified from Brent et al, A somitic compartment of tendon progenitors, Cell 2003
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f00aa1edf51af7e3f9c4e7ee36a11676
https://doi.org/10.17504/protocols.io.p33dqqn
https://doi.org/10.17504/protocols.io.p33dqqn
Autor:
Norma P. Gerard, Juan Manuel González-Rosa, Niranjana Natarajan, Lucas H. Cocco-Delgado, Michka Sharpe, Calum A. MacRae, Nhi Ngoc Ho, Jessica L. Whited, Aysu Uygur, Craig Gerard, Caroline E. Burns, Richard T. Lee, Donald M. Bryant, C. Geoffrey Burns, Yamen Abbas
Background: Defining conserved molecular pathways in animal models of successful cardiac regeneration could yield insight into why adult mammals have inadequate cardiac regeneration after injury. Insight into the transcriptomic landscape of early car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cb6ef7050ede78259f1cfee645a4cb
https://europepmc.org/articles/PMC5953786/
https://europepmc.org/articles/PMC5953786/
Autor:
Joseph Gannon, Gregory F. Egnaczyk, Kenneth D. Poss, Caitlin C. O'Meara, Ahmed I. Mahmoud, Long Zhao, Donald M. Bryant, Richard T. Lee, Ruimao Zheng, Caroline E. Burns, Wen-Yee Choi, Calum A. MacRae, Lei Cai, C. Geoffrey Burns, Matthew Gemberling
Publikováno v:
Developmental Cell. 34(4):387-399
SummarySome organisms, such as adult zebrafish and newborn mice, have the capacity to regenerate heart tissue following injury. Unraveling the mechanisms of heart regeneration is fundamental to understanding why regeneration fails in adult humans. Nu
Publikováno v:
Journal of Molecular and Cellular Cardiology. 79:315-318
The finding that neonatal mice are able to regenerate myocardium after apical resection has recently been questioned. We determined if heart regeneration is influenced by the size of cardiac resection and whether surgical retraction of the ventricula