Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Donald Lyerly"'
Autor:
Elizabeth Nixon, Joseph Boyer, Sue Holland, Isabel Saiz-Nicolas, Donald Lyerly, William Gannon, Jason Nichols, Beatriz Sanfiz-Pinto, Darren Rimmer, Brian Lupotsky, Paul Kadwill, Rob Hughes, Ioana Popa-Burke
Publikováno v:
SLAS Discovery. 14:1017-1030
Since the advent of high-throughput screening (HTS) in the early 1990s, parallel multichannel liquid handlers have become a mainstay in every drug discovery setting. Although several peer-reviewed publications have discussed methods and criteria for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321f84f62b180ddd1c41ed9840a3f0bf
https://doi.org/10.1177/1087057109339938
https://doi.org/10.1177/1087057109339938
Autor:
Jessica E. Matthews, Wen-Ji Chen, Kerry J Koller, Richard F. Cox, Alejandro J. Daniels, Donald Lyerly, Marilyn Jansen
Publikováno v:
Regulatory Peptides. 72:113-119
Neuropeptide Y (NPY) is widely distributed throughout the central and peripheral nervous system and exerts a wide range of physiological responses by activating specific receptors. In this study we have characterized the potency of the high affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05ac25857955ba7bf799d0db9b1265c
https://doi.org/10.1016/s0167-0115(97)01044-6
https://doi.org/10.1016/s0167-0115(97)01044-6
Autor:
Peter J. Gengo, Michael J. Durcan, Ching M. Wang, Anne V. Russell, Philip F. Morgan, Ronald M. Norton, Barrett R. Cooper, Stacy A. Jones-Humble, Richard F. Cox, Donald Lyerly, Flora L.M. Tang, Michael J. Watson
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 15(3)
11192U90 was submitted to receptor binding and monoamine uptake assays. It bound potently at serotonin 5-HT2, dopaminergic D2, serotonin 5-HT1A, and adrenergic alpha 1 and alpha 2 receptors. It also bound to dopaminergic D1, serotonin 5-HT3, serotoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6d87f697c4f774b5f233f30d8a0380
https://pubmed.ncbi.nlm.nih.gov/8873105
https://pubmed.ncbi.nlm.nih.gov/8873105
Autor:
Donald Lyerly, Stephanie Padilla
Publikováno v:
Journal of neurochemistry. 46(4)
Rapid axonal transport of glycoproteins was examined in the retinofugal projections of hypothermic and normothermic adult male Long-Evans hooded rats previously receiving intraocular injections of [3H]fucose. The amount of retinal fucosylation appear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6c2fd3c5cb0c195fc3d24179ee1ef0
https://pubmed.ncbi.nlm.nih.gov/2419507
https://pubmed.ncbi.nlm.nih.gov/2419507
Autor:
Donald Lyerly, Stephanie Padilla
Publikováno v:
Toxicology and applied pharmacology. 101(3)
Although the solvent xylene is suspected of producing nervous system dysfunction in animals and humans, little is known regarding the neurochemical consequences of xylene inhalation. The intent of this study was to determine the effect of intermitten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69d6f1b69a4d1b688dfc5d540b13203
https://pubmed.ncbi.nlm.nih.gov/2603159
https://pubmed.ncbi.nlm.nih.gov/2603159
Publikováno v:
Toxicology and applied pharmacology. 87(2)
Organophosphorus compounds which, after acute administration, inhibit neurotoxic esterase (NTE) by greater than or equal to 65% and undergo a subsequent "aging" reaction, produce a delayed neuropathy characterized by degeneration of large and long ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef0908e9749d3ec65d07e5a9de6d88c
https://pubmed.ncbi.nlm.nih.gov/3824383
https://pubmed.ncbi.nlm.nih.gov/3824383