Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Donald Lloyd-Jones"'
Autor:
Mary M. McDermott, Christopher R. Martens, Kathryn J. Domanchuk, Dongxue Zhang, Clara B. Peek, Michael H. Criqui, Luigi Ferrucci, Philip Greenland, Jack M. Guralnik, Karen J. Ho, Melina R. Kibbe, Kate Kosmac, Donald Lloyd-Jones, Charlotte A. Peterson, Robert Sufit, Lu Tian, Stephanie Wohlgemuth, Lihui Zhao, Pei Zhu, Christiaan Leeuwenburgh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract People with lower extremity peripheral artery disease (PAD) have increased oxidative stress, impaired mitochondrial activity, and poor walking performance. NAD+ reduces oxidative stress and is an essential cofactor for mitochondrial respirat
Externí odkaz:
https://doaj.org/article/2c373f254eb346318d878694e2b1a44e
Autor:
Yana Hrytsenko, Benjamin Shea, Michael Elgart, Nuzulul Kurniansyah, Genevieve Lyons, Alanna C. Morrison, April P. Carson, Bernhard Haring, Braxton D. Mitchell, Bruce M. Psaty, Byron C. Jaeger, C. Charles Gu, Charles Kooperberg, Daniel Levy, Donald Lloyd-Jones, Eunhee Choi, Jennifer A. Brody, Jennifer A. Smith, Jerome I. Rotter, Matthew Moll, Myriam Fornage, Noah Simon, Peter Castaldi, Ramon Casanova, Ren-Hua Chung, Robert Kaplan, Ruth J. F. Loos, Sharon L. R. Kardia, Stephen S. Rich, Susan Redline, Tanika Kelly, Timothy O’Connor, Wei Zhao, Wonji Kim, Xiuqing Guo, Yii-Der Ida Chen, The Trans-Omics in Precision Medicine Consortium, Tamar Sofer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract We construct non-linear machine learning (ML) prediction models for systolic and diastolic blood pressure (SBP, DBP) using demographic and clinical variables and polygenic risk scores (PRSs). We developed a two-model ensemble, consisting of
Externí odkaz:
https://doaj.org/article/322241f378754ea881e603a18375361b
Autor:
Laura E Schanberg, Ann M Reed, Christoph P Hornik, Kaveh Ardalan, Hwanhee Hong, Bryce B Reeve, Rebecca Sadun, M Anthony Moody, Eveline Y Wu, Donald Lloyd-Jones, Angel Davalos, Audrey Ward, Jeffrey Dvergsten, Mark Connelly
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/0096cbc7a7684b08ac2476422c6594b5
Autor:
Sherry-Ann Brown, Craig Beavers, Brenton Bauer, Richard K. Cheng, Generika Berman, Catherine H. Marshall, Avirup Guha, Prantesh Jain, Austin Steward, Jeanne M. DeCara, Iredia M. Olaye, Kathryn Hansen, Jim Logan, Carmen Bergom, Carri Glide-Hurst, Irving Loh, John Alan Gambril, James MacLeod, Ragasnehith Maddula, Peter J. McGranaghan, Akshee Batra, Courtney Campbell, Abdulaziz Hamid, Fatma Gunturkun, Robert Davis, John Jefferies, Michael Fradley, Katherine Albert, Anne Blaes, Indrajit Choudhuri, Arjun K. Ghosh, Thomas D. Ryan, Ogochukwu Ezeoke, Douglas J. Leedy, Wadsworth Williams, Sebastian Roman, Lorenz Lehmann, Abdullah Sarkar, Diego Sadler, Elizabeth Polter, Kathryn J. Ruddy, Neha Bansal, Eric Yang, Brijesh Patel, David Cho, Alison Bailey, Daniel Addison, Vijay Rao, Joshua E. Levenson, Dipti Itchhaporia, Karol Watson, Martha Gulati, Kim Williams, Donald Lloyd-Jones, Erin Michos, Julie Gralow, Hugo Martinez
Publikováno v:
American Heart Journal Plus, Vol 38, Iss , Pp 100354- (2024)
As cancer therapies increase in effectiveness and patients' life expectancies improve, balancing oncologic efficacy while reducing acute and long-term cardiovascular toxicities has become of paramount importance. To address this pressing need, the Ca
Externí odkaz:
https://doaj.org/article/8043007b5ee04ac89d1b9f4d2fd3cdc7
Autor:
Craig Sable, Jennifer S. Li, Martin Tristani‐Firouzi, Angela Fagerlin, Robert M. Silver, Mark Yandel, H. Joseph Yost, Andrea Beaton, James Dale, Mark Emmanuel Engel, David Watkins, Christopher Spurney, Asheley C. Skinner, Sarah C. Armstrong, Svati H. Shah, Norrina Allen, Matthew Davis, Lifang Hou, Linda Van Horn, Darwin Labarthe, Donald Lloyd‐Jones, Bradley Marino
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 7 (2023)
The American Heart Association's Strategically Focused Children's Research Network started in July 2017 with 4 unique programs at Children's National Hospital in Washington, DC; Duke University in Durham, North Carolina; University of Utah in Salt La
Externí odkaz:
https://doaj.org/article/a1c23aa891184b32b4c7b9d4ca6b6793
Autor:
Karen Y. He, Tanika N. Kelly, Heming Wang, Jingjing Liang, Luke Zhu, Brian E. Cade, Themistocles L. Assimes, Lewis C. Becker, Amber L. Beitelshees, Lawrence F. Bielak, Adam P. Bress, Jennifer A. Brody, Yen-Pei Christy Chang, Yi-Cheng Chang, Paul S. de Vries, Ravindranath Duggirala, Ervin R. Fox, Nora Franceschini, Anna L. Furniss, Yan Gao, Xiuqing Guo, Jeffrey Haessler, Yi-Jen Hung, Shih-Jen Hwang, Marguerite Ryan Irvin, Rita R. Kalyani, Ching-Ti Liu, Chunyu Liu, Lisa Warsinger Martin, May E. Montasser, Paul M. Muntner, Stanford Mwasongwe, Take Naseri, Walter Palmas, Muagututi’a Sefuiva Reupena, Kenneth M. Rice, Wayne H.-H. Sheu, Daichi Shimbo, Jennifer A. Smith, Beverly M. Snively, Lisa R. Yanek, Wei Zhao, John Blangero, Eric Boerwinkle, Yii-Der Ida Chen, Adolfo Correa, L. Adrienne Cupples, Joanne E. Curran, Myriam Fornage, Jiang He, Lifang Hou, Robert C. Kaplan, Sharon L. R. Kardia, Eimear E. Kenny, Charles Kooperberg, Donald Lloyd-Jones, Ruth J. F. Loos, Rasika A. Mathias, Stephen T. McGarvey, Braxton D. Mitchell, Kari E. North, Patricia A. Peyser, Bruce M. Psaty, Laura M. Raffield, D. C. Rao, Susan Redline, Alex P. Reiner, Stephen S. Rich, Jerome I. Rotter, Kent D. Taylor, Russell Tracy, Ramachandran S. Vasan, The Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Alanna C. Morrison, Daniel Levy, Aravinda Chakravarti, Donna K. Arnett, Xiaofeng Zhu
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background While large genome-wide association studies have identified nearly one thousand loci associated with variation in blood pressure, rare variant identification is still a challenge. In family-based cohorts, genome-wide linkage scans
Externí odkaz:
https://doaj.org/article/ef3227d670ad41388d430a8ee8f9216c
Autor:
Ann Marie Navar, Lawrence J. Fine, Walter T. Ambrosius, Arleen Brown, Pamela S. Douglas, Karen Johnson, Amit V. Khera, Donald Lloyd-Jones, Erin D. Michos, Mahasin Mujahid, Daniel Muñoz, Khurram Nasir, Nicole Redmond, Paul M Ridker, Jennifer Robinson, David Schopfer, Deborah F. Tate, Cora E. Lewis
Publikováno v:
American Journal of Preventive Cardiology, Vol 12, Iss , Pp 100430- (2022)
More than half of U.S. young adults have low ten-year but high lifetime risk of cardiovascular disease (CVD). Improving primary prevention in young adulthood may help reduce persistent CVD disparities and overall CVD morbidity and mortality. The Nati
Externí odkaz:
https://doaj.org/article/368f82e0dc1b42dfa35137415f3f5c08
Autor:
Nour Makarem, Cecilia Castro‐Diehl, Marie‐Pierre St‐Onge, Susan Redline, Steven Shea, Donald Lloyd‐Jones, Hongyan Ning, Brooke Aggarwal
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 21 (2022)
Background Although sufficient and healthy sleep is inversely associated with cardiovascular disease (CVD) and its risk factors, the American Heart Association's Life's Simple 7 (LS7), as a measure of cardiovascular health (CVH), did not include slee
Externí odkaz:
https://doaj.org/article/6ca1506c94d24053aee868629efe98bd
Autor:
Kausik K. Ray, Brian A. Ference, Tania Séverin, Dirk Blom, Stephen J. Nicholls, Mariko H. Shiba, Wael Almahmeed, Rodrigo Alonso, Magdalena Daccord, Marat Ezhov, Rosa Fernández Olmo, Piotr Jankowski, Fernando Lanas, Roopa Mehta, Raman Puri, Nathan D. Wong, David Wood, Dong Zhao, Samuel S. Gidding, Salim S. Virani, Donald Lloyd-Jones, Fausto Pinto, Pablo Perel, Raul D. Santos
Publikováno v:
Global Heart, Vol 17, Iss 1 (2022)
Background: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue to be major causes of premature death, disability and healthcare expenditure globally. Preventing the accumul
Externí odkaz:
https://doaj.org/article/d76f2dee03ca4cf1b6165d59d556f094
Autor:
Miguel Cainzos‐Achirica, Renato Quispe, Reed Mszar, Ramzi Dudum, Mahmoud Al Rifai, Raimund Erbel, Andreas Stang, Karl‐Heinz Jöckel, Nils Lehmann, Sara Schramm, Börge Schmidt, Peter P. Toth, Jamal S. Rana, Joao A. C. Lima, Henrique Doria de Vasconcellos, Donald Lloyd‐Jones, Parag H. Joshi, Colby Ayers, Amit Khera, Michael J. Blaha, Philip Greenland, Khurram Nasir
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 16 (2022)
Background The value of coronary artery calcium (CAC) in the allocation of PCSK9i (proprotein convertase subtilisin/kexin type 9 inhibitors) among individuals without clinically evident atherosclerotic cardiovascular disease (ASCVD) is unknown for in
Externí odkaz:
https://doaj.org/article/2a86dc1a2d4545368ad220f398916818