Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Donald L. K. Kau"'
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 47:599-608
Human Factor Xa is a trypsin-like serine protease, which serves a critical role in blood coagulation events. LY517717 is currently under clinical investigation as a Factor Xa inhibitor. To support the ADME studies, LY517717 was synthesized using D-ph
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:273-295
The [3H]- and two [14C]-isotopomers of 8β-[(methylthio)methyl]-6-propylergoline mesylate (pergolide mesylate) have been synthesized. The [3H]-derivative was synthesized by the palladium catalyzed tritiation of the corresponding 6-allyl derivative. R
Publikováno v:
Antimicrobial Agents and Chemotherapy. 10:630-638
The metabolic fate of the orally effective cephalosporin antibiotic cefaclor (Lilly 99638) has been studied in rats, mice, and dogs. Cefaclor is efficiently absorbed from the gastrointestinal tract as the intact antibiotic. In rats and mice, cefaclor