Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Donald L. Helseth"'
Autor:
Talent Theparee, Michael Akroush, Linda M. Sabatini, Vivien Wang, Kathy A. Mangold, Nora Joseph, Susan Jane Stocker, Alexa Freedman, Donald L. Helseth, Mark S. Talamonti, Karen L. Kaul
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Detection of circulating tumor DNA (ctDNA) from plasma cell free DNA (cfDNA) has shown promise for diagnosis, therapeutic targeting, and prognosis. This study explores ctDNA detection by next generation sequencing (NGS) and associated clinic
Externí odkaz:
https://doaj.org/article/c2862a43ede147a1ac8eb6ad923f7199
Autor:
Sean P. David, Henry M. Dunnenberger, Sarah Choi, Allison DePersia, Nadim Ilbawi, Christopher Ward, Dyson T. Wake, Janardan D. Khandekar, Yvette Shannon, Kristen Hughes, Nicholas Miller, Kathy A. Mangold, Linda M. Sabatini, Donald L. Helseth, Jianfeng Xu, Alan Sanders, Karen L. Kaul, Peter J. Hulick
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Genomic and personalized medicine implementation efforts have largely centered on specialty care in tertiary health systems. There are few examples of fully integrated care systems that span the healthcare continuum. In 2014, NorthShore University He
Externí odkaz:
https://doaj.org/article/8d8d123c992c44b8bc21a5215773cee4
Autor:
Aileen C. Tartanian, Nicole Mulroney, Kelly Poselenzny, Michael Akroush, Trevor Unger, Donald L. Helseth, Linda M. Sabatini, Michael Bouma, Paige M. K. Larkin
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/b80de911408d4e4a84bf46e8dabba3d5
Autor:
Aileen C. Tartanian, Nicole Mulroney, Kelly Poselenzny, Michael Akroush, Trevor Unger, Donald L. Helseth, Linda M. Sabatini, Michael Bouma, Paige M.K. Larkin
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
Identification of SARS-CoV-2 lineages has shown to provide invaluable information regarding treatment efficacy, viral transmissibility, disease severity, and immune evasion. These benefits provide institutions with an expectation of high informationa
Externí odkaz:
https://doaj.org/article/8e4350f7055d44feb945accaa8d7400c
Autor:
Yuefeng Yang, Feng-Jun Xiao, Kathy A. Mangold, Yuan Ji, Megan E. Sullivan, Jinnan Li, Hao Wang, Xiaoyan Zhang, Prem Seth, Yitan Zhu, Xuejie Wu, Kamalakar Gulukota, Weidong Xu, Bellur S. Prabhakar, Lisheng Wang, Donald L. Helseth, Edward Wang, Hua Wang, Karen L. Kaul, Di Peng
Publikováno v:
Hum Gene Ther
In an effort to develop a new therapy for cancer and to improve antiprogrammed death inhibitor-1 (anti-PD-1) and anticytotoxic T lymphocyte-associated protein (anti-CTLA-4) responses, we have created a telomerase reverse transcriptase promoter-regula
Autor:
Donald L. Helseth, Karen L. Kaul, Janaradan D. Khandekar, Dyson T. Wake, Mathew Yang, Peter J. Hulick, Kamalakar Gulukota, Nicholas Miller, Mike Bouma, Henry M. Dunnenberger, Tom Werth, Linda Sabatini
Publikováno v:
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
The advent of next generation DNA sequencing (NGS) has revolutionized clinical medicine by enabling wide‐spread testing for genomic anomalies and polymorphisms. With that explosion in testing, however, come several informatics challenges including
Autor:
Edward Wang, Karen L. Kaul, Yuefeng Yang, Weidong Xu, Kamalakar Gulukota, Poornima Saha, Maria Head, Megan E. Sullivan, Bellur S. Prabhkar, Donald L. Helseth, Hans Schreiber, Zebin Hu, Kathy A. Mangold, Theresa A. Guise, Prem Seth
Publikováno v:
Hum Gene Ther
We report here the development of oncolytic adenoviruses (Ads) that have reduced toxicity, enhanced tumor tropism, produce strong antitumor response, and can overcome resistance to immune checkpoint inhibitor therapy in breast cancer. We have shown t
Autor:
Beatriz Aguirre, Miguel Costas, Nallely Cabrera, Guillermo Mendoza-Hernández, Donald L Helseth, Paulette Fernández, Marietta Tuena de Gómez-Puyou, Ruy Pérez-Montfort, Alfredo Torres-Larios, Armando Gómez Puyou
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21035 (2011)
We previously observed that human homodimeric triosephosphate isomerase (HsTIM) expressed in Escherichia coli and purified to apparent homogeneity exhibits two significantly different thermal transitions. A detailed exploration of the phenomenon show
Externí odkaz:
https://doaj.org/article/2a53e907361e4ef483df69e839d9b7bd
Autor:
Daniel H. Shevrin, Peter J. Hulick, Elizabeth Humphries, Samuel R. Denmeade, Sarah D. Isaacs, Jacqueline Petkewicz, Michael McGuire, Misop Han, Kathleen E. Wiley, H.B. Carter, Charles M. Ewing, Alan Alan, Michael A. Carducci, Xu Liu, Yishuo Wu, Rong Na, Liti Zhang, Patrick C. Walsh, Mario A. Eisenberger, Charles B. Brendler, Sameep Shah, Kristian Novakovic, Margo Quinn, Brian T. Helfand, Hongjie Yu, Chi-Hsiung Wang, Jianfeng Xu, Deke Jiang, William B. Isaacs, Donald L. Helseth, Ning Zhang, Qiang Ding, S. Lilly S. Lilly, Zhoujun Shen, Janardan D. Khandekar, Kamalakar Gulukota, Kathleen A. Cooney
Publikováno v:
Journal of Urology. 197
Autor:
Donald L. Helseth, Sarah D. Isaacs, Liti Zhang, Mario A. Eisenberger, Xu Liu, Margo Quinn, Michael McGuire, Brian T. Helfand, Sameep Shah, Kristian Novakovic, Patrick C. Walsh, Charles M. Ewing, Elizabeth Humphries, Alan W. Partin, Charles B. Brendler, Michael A. Carducci, Peter J. Hulick, S. Lilly Zheng, Qiang Ding, Janardan D. Khandekar, Daniel H. Shevrin, Kathleen E. Wiley, Kamalakar Gulukota, Chi Hsiung Wang, Hongjie Yu, Kathleen A. Cooney, Zhoujun Shen, Rong Na, Samuel R. Denmeade, Misop Han, Deke Jiang, Jacqueline Petkewicz, Yishuo Wu, William B. Isaacs, Ning Zhang, H. Ballentine Carter, Jianfeng Xu
Publikováno v:
European Urology Supplements. 16:e832-e833
Germline mutations in BRCA1/2 and ATM have been associated with prostate cancer (PCa) risk.To directly assess whether germline mutations in these three genes distinguish lethal from indolent PCa and whether they confer any effect on age at death.A re