Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Donald L Atkinson"'
Autor:
Sarah E Mercer, Chia-Ho Cheng, Donald L Atkinson, Jennifer Krcmery, Claudia E Guzman, David T Kent, Katherine Zukor, Kenneth A Marx, Shannon J Odelberg, Hans-Georg Simon
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52375 (2012)
The inability to functionally repair tissues that are lost as a consequence of disease or injury remains a significant challenge for regenerative medicine. The molecular and cellular processes involved in complete restoration of tissue architecture a
Externí odkaz:
https://doaj.org/article/b76d611a6820446692269f0b08a6b69f
Autor:
Christopher A. Simeone, Joseph L. Wilkerson, Annelise M. Poss, James A. Banks, Joseph V. Varre, Jose Lazaro Guevara, Edgar Javier Hernandez, Bushra Gorsi, Donald L. Atkinson, Tursun Turapov, Scott G. Frodsham, Julio C. Fierro Morales, Kristina O’Neil, Barry Moore, Mark Yandell, Scott A. Summers, Andrzej S. Krolewski, William L. Holland, Marcus G. Pezzolesi
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Adiponectin, encoded by ADIPOQ, is an insulin-sensitizing, anti-inflammatory, and renoprotective adipokine that activates receptors with intrinsic ceramidase activity. We identified a family harboring a 10-nucleotide deletion mutation in ADI
Externí odkaz:
https://doaj.org/article/250d25ef59fc4c589b2a1e3ae70ec7b4
Autor:
Christopher A. Simeone, Joseph L. Wilkerson, Annelise M. Poss, James A. Banks, Joseph V. Varre, Jose Lazaro Guevara, Edgar Javier Hernandez, Bushra Gorsi, Donald L. Atkinson, Tursun Turapov, Scott G. Frodsham, Julio C. Fierro Morales, Kristina O’Neil, Barry Moore, Mark Yandell, Scott A. Summers, Andrzej S. Krolewski, William L. Holland, Marcus G. Pezzolesi
Publikováno v:
NPJ genomic medicine. 7(1)
Adiponectin, encoded by ADIPOQ, is an insulin-sensitizing, anti-inflammatory, and renoprotective adipokine that activates receptors with intrinsic ceramidase activity. We identified a family harboring a 10-nucleotide deletion mutation in ADIPOQ that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7575e283299106a2e60122c72e7f780f
https://pubmed.ncbi.nlm.nih.gov/35869090
https://pubmed.ncbi.nlm.nih.gov/35869090
Autor:
Márcio, Buffolo, Karla Maria, Pires, Maroua, Ferhat, Olesya, Ilkun, Aman, Makaju, Alan, Achenbach, Faith, Bowman, Donald L, Atkinson, William L, Holland, Ez-Zoubir, Amri, Bhagirath, Chaurasia, Sarah, Franklin, Sihem, Boudina
Publikováno v:
Cell reports. 29(2)
Accumulation of visceral (VIS) is a predictor of metabolic disorders and insulin resistance. This is due in part to the limited capacity of VIS fat to buffer lipids allowing them to deposit in insulin-sensitive tissues. Mechanisms underlying selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7f7fd9a6f9687ba72b7f168e46c0294
https://pubmed.ncbi.nlm.nih.gov/31597091
https://pubmed.ncbi.nlm.nih.gov/31597091
Autor:
Donald L. Atkinson, Warren Sherman, David A. Bull, Dolly J. Holt, David W. Grainger, V. Vargas, Monica P. Revelo, Amit N. Patel, F. Silva, Sihem Boudina, James W. Yockman
Publikováno v:
Stem Cells. 32:572-581
Brown adipose tissue (BAT) plays a key role in the evolutionarily conserved mechanisms underlying energy homeostasis in mammals. It is characterized by fat vacuoles 5–10 μm in diameter and expression of uncoupling protein one, central to the regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1628caa456eb01ebfc2171178d350b9d
https://doi.org/10.1002/stem.1595
https://doi.org/10.1002/stem.1595
Autor:
Amalia A. Winters, Jose A. Hawayek, Hallie Thorp, Donald L. Atkinson, F. Silva, Edward W. Hsu, Sophia Bou-Ghannam, C. Bartlett, David A. Grainger, Alonso P. Moreno, Amit N. Patel
Publikováno v:
Cell Transplantation, Vol 25 (2016)
The development of cell- and gene-based strategies for regenerative medicine offers a therapeutic option for the repair and potential regeneration of damaged cardiac tissue post-myocardial infarction (MI). Human umbilical cord subepithelial cell-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f040ca71c743785cf3b9c78eed800f3
https://doaj.org/article/29dbd15b6ede49a985e7039e45fda0ba
https://doaj.org/article/29dbd15b6ede49a985e7039e45fda0ba
Autor:
Timothy E. Graham, Scott A. Summers, Bhagirath Chaurasia, Jinjin Cai, Ashot Sargsyan, Karla Maria Pereira Pires, Sihem Boudina, Ma´rcio A. Buffolo, Maroua Ferhat, Rana Smalling, Donald L. Atkinson
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1708-1717.e5 (2018)
Summary: Autophagy is a homeostatic cellular process involved in the degradation of long-lived or damaged cellular components. The role of autophagy in adipogenesis is well recognized, but its role in mature adipocyte function is largely unknown. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d123342b2eb8d8e9bba58bdf54c8d9bc
https://doi.org/10.1016/j.celrep.2018.10.040
https://doi.org/10.1016/j.celrep.2018.10.040
Autor:
Mark T. Keating, Vladimir Vinarsky, Shannon J. Odelberg, Donald L. Atkinson, Tamara J. Stevenson
Publikováno v:
Developmental Dynamics. 235:606-616
Matrix metalloproteinase (MMP) activity is important for newt limb regeneration. In most biological processes that require MMP function, MMP activity is tightly controlled by a variety of mechanisms, including the coexpression of natural inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6566ddca74d5c1e9d029648e88b05ef1
https://doi.org/10.1002/dvdy.20654
https://doi.org/10.1002/dvdy.20654
Autor:
Donald L. Atkinson, Jiaxiang Shen, Michael C. Sanguinetti, M T Keating, Anruo Zou, Mark E. Curran, Peter S. Spector
Publikováno v:
Nature. 384:80-83
THE slowly activating delayed-rectifier K+ current, IKS, modulates the repolarization of cardiac action potentials. The molecular structure of the IKS channel is not known, but physiological data indicate that one component of theIKSchannel is minK (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc209ffd5668b7f2de445688bb47e83
https://doi.org/10.1038/384080a0
https://doi.org/10.1038/384080a0
Autor:
Peter J. Schwartz, T. De Jager, Mark E. Curran, M T Keating, J.A. Towbin, J. M. Millholland, Gregory M. Landes, Igor Splawski, Katherine W. Timothy, T. J. VanRaay, Donald L. Atkinson, Timothy C. Burn, Timothy D. Connors, Qing Wang, Vincent Gm, Jiaxiang Shen, Arthur J. Moss
Publikováno v:
Nature Genetics. 12:17-23
Genetic factors contribute to the risk of sudden death from cardiac arrhythmias. Here, positional cloning methods establish KVLQT1 as the chromosome 11-linked LQT1 gene responsible for the most common inherited cardiac arrhythmia. KVLQT1 is strongly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92869456f5ca6916ed214d37ee56ad42
https://doi.org/10.1038/ng0196-17
https://doi.org/10.1038/ng0196-17