Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Donald L, Siegel"'
Autor:
Jerry A. Holmberg, Stephen M. Henry, Thierry Burnouf, Dana Devine, Susanne Marschner, Thomas C. Boothby, Scott R. Burger, Stella T. Chou, Brian Custer, Neil Blumberg, Donald L. Siegel, Steven L. Spitalnik
Publikováno v:
Transfusion. 62:2391-2404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e137558a926c125deb0690a63089840
https://doi.org/10.1111/trf.17092
https://doi.org/10.1111/trf.17092
Autor:
J. Joseph Melenhorst, Gregory M. Chen, Meng Wang, David L. Porter, Changya Chen, McKensie A. Collins, Peng Gao, Shovik Bandyopadhyay, Hongxing Sun, Ziran Zhao, Stefan Lundh, Iulian Pruteanu-Malinici, Christopher L. Nobles, Sayantan Maji, Noelle V. Frey, Saar I. Gill, Alison W. Loren, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, David E. Ambrose, Megan M. Davis, Joseph A. Fraietta, Jennifer L. Brogdon, Regina M. Young, Anne Chew, Bruce L. Levine, Donald L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F. Lacey, Kai Tan, Carl H. June
Publikováno v:
Nature. 602:503-509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eae92a42be329dd0e4c7cfaa15f42a8
https://doi.org/10.1038/s41586-021-04390-6
https://doi.org/10.1038/s41586-021-04390-6
Autor:
In-Young Jung, Vivek Narayan, Sierra McDonald, Andrew J. Rech, Robert Bartoszek, Gwanui Hong, Megan M. Davis, Jun Xu, Alina C. Boesteanu, Julie S. Barber-Rotenberg, Gabriela Plesa, Simon F. Lacey, Julie K. Jadlowsky, Donald L. Siegel, Dana M. Hammill, Park F. Cho-Park, Shelley L. Berger, Naomi B. Haas, Joseph A. Fraietta
Publikováno v:
Science Translational Medicine. 14
Chimeric antigen receptor (CAR) T cells have not induced meaningful clinical responses in solid tumors. Loss of T cell stemness, poor expansion capacity, and exhaustion during prolonged tumor antigen exposure are major causes of CAR T cell therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05e848faa2d1976b65586f5703fc0d1
https://doi.org/10.1126/scitranslmed.abn7336
https://doi.org/10.1126/scitranslmed.abn7336
Autor:
Saar Gill, Vanessa Vides, Noelle V. Frey, Elizabeth O. Hexner, Susan Metzger, Megan O'Brien, Wei-Ting Hwang, Jennifer L. Brogdon, Megan M. Davis, Joseph A. Fraietta, Avery L. Gaymon, Whitney L. Gladney, Simon F. Lacey, Anne Lamontagne, Anthony R. Mato, Marcela V. Maus, J. Joseph Melenhorst, Edward Pequignot, Marco Ruella, Maksim Shestov, John C. Byrd, Stephen J. Schuster, Donald L. Siegel, Bruce L. Levine, Carl H. June, David L. Porter
Publikováno v:
Blood advances. 6(21)
In chronic lymphocytic leukemia (CLL) patients who achieve a complete remission (CR) to anti-CD19 chimeric antigen receptor T cells (CART-19), remissions are remarkably durable. Preclinical data suggesting synergy between CART-19 and the Bruton’s t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8def37648cb5d5a699edfc25ad44fdeb
https://pubmed.ncbi.nlm.nih.gov/35349631
https://pubmed.ncbi.nlm.nih.gov/35349631
Autor:
J. Joseph Melenhorst, Gregory M. Chen, Meng Wang, David L. Porter, Changya Chen, McKensie A. Collins, Peng Gao, Shovik Bandyopadhyay, Hongxing Sun, Ziran Zhao, Stefan Lundh, Iulian Pruteanu-Malinici, Christopher L. Nobles, Sayantan Maji, Noelle V. Frey, Saar I. Gill, Alison W. Loren, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, David E. Ambrose, Megan M. Davis, Joseph A. Fraietta, Jennifer L. Brogdon, Regina M. Young, Anne Chew, Bruce L. Levine, Donald L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F. Lacey, Kai Tan, Carl H. June
Publikováno v:
Nature. 612:E22-E22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1793d4b78f14557a923b8b96eaf9fa8a
https://doi.org/10.1038/s41586-022-05376-8
https://doi.org/10.1038/s41586-022-05376-8
Autor:
Vivek, Narayan, Julie S, Barber-Rotenberg, In-Young, Jung, Simon F, Lacey, Andrew J, Rech, Megan M, Davis, Wei-Ting, Hwang, Priti, Lal, Erica L, Carpenter, Shannon L, Maude, Gabriela, Plesa, Neha, Vapiwala, Anne, Chew, Michael, Moniak, Ronnie A, Sebro, Michael D, Farwell, Amy, Marshall, Joan, Gilmore, Lester, Lledo, Karen, Dengel, Sarah E, Church, Tyler D, Hether, Jun, Xu, Mercy, Gohil, Thomas H, Buckingham, Stephanie S, Yee, Vanessa E, Gonzalez, Irina, Kulikovskaya, Fang, Chen, Lifeng, Tian, Kyle, Tien, Whitney, Gladney, Christopher L, Nobles, Hayley E, Raymond, Elizabeth O, Hexner, Donald L, Siegel, Frederic D, Bushman, Carl H, June, Joseph A, Fraietta, Bruce L, Levine
Publikováno v:
Nature medicine. 28(4)
Chimeric antigen receptor (CAR) T cells have demonstrated promising efficacy, particularly in hematologic malignancies. One challenge regarding CAR T cells in solid tumors is the immunosuppressive tumor microenvironment (TME), characterized by high l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7bb7fa879c20cb8e11ab244db1c24b2
https://pubmed.ncbi.nlm.nih.gov/35411068
https://pubmed.ncbi.nlm.nih.gov/35411068
Autor:
J Joseph, Melenhorst, Gregory M, Chen, Meng, Wang, David L, Porter, Changya, Chen, McKensie A, Collins, Peng, Gao, Shovik, Bandyopadhyay, Hongxing, Sun, Ziran, Zhao, Stefan, Lundh, Iulian, Pruteanu-Malinici, Christopher L, Nobles, Sayantan, Maji, Noelle V, Frey, Saar I, Gill, Alison W, Loren, Lifeng, Tian, Irina, Kulikovskaya, Minnal, Gupta, David E, Ambrose, Megan M, Davis, Joseph A, Fraietta, Jennifer L, Brogdon, Regina M, Young, Anne, Chew, Bruce L, Levine, Donald L, Siegel, Cécile, Alanio, E John, Wherry, Frederic D, Bushman, Simon F, Lacey, Kai, Tan, Carl H, June
Publikováno v:
Nature. 602(7897)
The adoptive transfer of T lymphocytes reprogrammed to target tumour cells has demonstrated potential for treatment of various cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06b0e9624ef1737ea81ae7c99f13ec3f
https://pubmed.ncbi.nlm.nih.gov/36477542
https://pubmed.ncbi.nlm.nih.gov/36477542
Publikováno v:
Biochemistry. 35:4306-4313
Direct NMR measurements of the folding kinetics are performed on a collagen-like triple helical peptide. The triple helical peptide was designed to model a biologically important region of collagen and has the sequence (POG)3ITGARGLAG(POG)4. Triple h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c585b760974c2d91d5b17ec057425004
https://doi.org/10.1021/bi952270d
https://doi.org/10.1021/bi952270d
Publikováno v:
FEBS Letters. 368:551-555
Electrostatic interactions were studied in a triple-helical peptide, (POG)3PKGQKGEKG(POG)4, which contains a lysine-rich 9 residue sequence from the collagen-like domain of the macrophage scavenger receptor (MSR). This peptide adopts a stable triple-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8a4f851617b59380fcef9bf4c2ff98
https://doi.org/10.1016/0014-5793(95)00738-u
https://doi.org/10.1016/0014-5793(95)00738-u