Zobrazeno 1 - 10
of 490
pro vyhledávání: '"Donald L, Price"'
Autor:
R. Wayne Albers, Donald L. Price
Basic Neurochemistry: Molecular, Cellular and Medical Aspects, a comprehensive text on neurochemistry, is now updated and revised in its Seventh Edition. This well-established text has been recognized worldwide as a resource for postgraduate train
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e421d9668a59a9d29f1b5febdedbbcd5
https://doi.org/10.7759/cureus.24319
https://doi.org/10.7759/cureus.24319
Autor:
Jayanth S. Chandran, Xian Lin, Agustin Zapata, Ahmet Höke, Mika Shimoji, Shonagh O'Leary Moore, Matthew P. Galloway, Fiona M. Laird, Philip C. Wong, Donald L. Price, Kathleen R. Bailey, Jacqueline N. Crawley, Toni Shippenberg, Huaibin Cai
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 3, Pp 505-514 (2008)
Loss-of-function mutations in the DJ-1 gene account for an autosomal recessive form of Parkinson's disease (PD). To investigate the physiological functions of DJ-1 in vivo, we generated DJ-1 knockout (DJ-1−/−) mice. Younger (
Externí odkaz:
https://doaj.org/article/df399a00a978488ebc81c32f71b401bb
Autor:
Alena Savonenko, Guilian M. Xu, Tatiana Melnikova, Johanna L. Morton, Victoria Gonzales, Molly P.F. Wong, Donald L. Price, Fai Tang, Alicja L. Markowska, David R. Borchelt
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 3, Pp 602-617 (2005)
Transgenic mice made by crossing animals expressing mutant amyloid precursor protein (APPswe) to mutant presenilin 1 (PS1dE9) allow for incremental increases in Aβ42 production and provide a model of Alzheimer-type amyloidosis. Here, we examine cogn
Externí odkaz:
https://doaj.org/article/655149e68b4d4aa99bd45795f6d21416
Publikováno v:
Neurobiology of Disease, Vol 14, Iss 1, Pp 133-145 (2003)
The present study was designed to examine whether brain inflammation caused by systemic administration of lipopolysaccharides (LPS) alters the expression/processing of amyloid precursor protein (APP) and increases the generation of amyloid β peptide
Externí odkaz:
https://doaj.org/article/64302519efe14993aa30a70dd177c5d3
Publikováno v:
Neurobiology of Disease, Vol 12, Iss 3, Pp 194-211 (2003)
Amyloid deposition appears to be an early and crucial event in Alzheimer’s disease (AD). To generate animal models of AD, mice expressing full-length amyloid precursor protein (APP), with mutations linked to FAD, have been created. These animals ex
Externí odkaz:
https://doaj.org/article/fd5a976eeb6d4d888e2ac2829326c61a
Autor:
Mitsunori Watanabe, Margaret Dykes-Hoberg, Valeria Cizewski Culotta, Donald L. Price, Philip C. Wong, Jeffrey D. Rothstein
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 6, Pp 933-941 (2001)
The mechanisms leading to neurodegeneration in ALS (amyotrophic lateral sclerosis) are not well understood, but cytosolic protein aggregates appear to be common in sporadic and familial ALS as well as transgenic mouse models expressing mutant Cu/Zn s
Externí odkaz:
https://doaj.org/article/9eb5061da769401186e6a95b7c012682
Autor:
Gabriele Schilling, Hyder A. Jinnah, Vicky Gonzales, Michael L. Coonfield, Yujin Kim, Jonathan D. Wood, Donald L. Price, Xiao-Jiang Li, Nancy Jenkins, Neal Copeland, Timothy Moran, Christopher A. Ross, David R. Borchelt
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 405-418 (2001)
Huntington's disease (HD) and Dentatorubral and pallidoluysian atrophy (DRPLA) are autosomal dominant, neurodegenerative disorders caused by the expansion of polyglutamine tracts in their respective proteins, huntingtin and atrophin-1. We have previo
Externí odkaz:
https://doaj.org/article/cbb632cb9c984806ad46071c59575f3c
Autor:
David R. Borchelt, Philip C. Wong, Mark W. Becher, Carlos A. Pardo, Michael K. Lee, Zuo-Shang Xu, Gopal Thinakaran, Nancy A. Jenkins, Neal G. Copeland, Sangram S. Sisodia, Don W. Cleveland, Donald L. Price, Paul N. Hoffman
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 1, Pp 27-35 (1998)
Superoxide dismutase 1 (SOD1), a ubiquitously expressed enzyme, detoxifies superoxide radicals and participates in copper homeostasis. Mutations in this enzyme have been linked to a subset of autosomal dominant cases of familial amyotrophic lateral s
Externí odkaz:
https://doaj.org/article/a84e546c32874331bb3496288a06ce73
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 1, Pp 17-26 (1998)
Peripheral nerve grafting into the central nervous system (CNS) has been used to study the regenerative capabilities of central neurons given access to a peripheral nervous system (PNS) environment. It is well documented that many CNS neurons regener
Externí odkaz:
https://doaj.org/article/0c1805cf425944329b8bf397c92e3c8f