Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Donald K. Nichols"'
Autor:
Malak Kotb, Paige E. Harrison, Donald K. Nichols, Taylor B. Chance, Holly A. Bloomfield, Nourtan F. Abdeltawab, Elizabeth E. Zumbrun, Aysegul Nalca
Publikováno v:
Viruses, Vol 4, Iss 12, Pp 3468-3493 (2012)
Countering aerosolized filovirus infection is a major priority of biodefense research. Aerosol models of filovirus infection have been developed in knock-out mice, guinea pigs and non-human primates; however, filovirus infection of immunocompetent mi
Externí odkaz:
https://doaj.org/article/0becb158ed7949429a0c7a6afbc8173d
Autor:
Donald K. Nichols, Roger D. Williams, Reese J. Baker, Nicole L. Garza, Nicholas R. Bramel, Paul A. Dabisch, Ty C. Hunter, John M. Dye, Holly A. Bloomfield, Elizabeth E. Zumbrun, Aysegul Nalca
Publikováno v:
Viruses, Vol 4, Iss 10, Pp 2115-2136 (2012)
Filoviruses are members of the genera Ebolavirus, Marburgvirus, and “Cuevavirus”. Because they cause human disease with high lethality and could potentially be used as a bioweapon, these viruses are classified as CDC Category A Bioterrorism Agent
Externí odkaz:
https://doaj.org/article/1b2481a632b54cf7ad078b852811535a
Autor:
John M. Dye, Kelly L. Warfield, Jay B. Wells, Robert C. Unfer, Sergey Shulenin, Hong Vu, Donald K. Nichols, M. Javad Aman, Sina Bavari
Publikováno v:
Viruses, Vol 8, Iss 4, p 94 (2016)
Marburg virus (MARV) was the first filovirus to be identified following an outbreak of viral hemorrhagic fever disease in Marburg, Germany in 1967. Due to several factors inherent to filoviruses, they are considered a potential bioweapon that could b
Externí odkaz:
https://doaj.org/article/07b8da8cb1d1426a810006e8564f79c6
Autor:
Casey C Perley, Rebecca L Brocato, Steven A Kwilas, Sharon Daye, Alicia Moreau, Donald K Nichols, Kelly S Wetzel, Joshua Shamblin, Jay W Hooper
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216700 (2019)
Hantaan virus (HTNV) and Puumala virus (PUUV) are rodent-borne hantaviruses that are the primary causes of hemorrhagic fever with renal syndrome (HFRS) in Europe and Asia. The development of well characterized animal models of HTNV and PUUV infection
Externí odkaz:
https://doaj.org/article/e3eef374354a4c02b74d26dc84d26885
Autor:
Aysegul Nalca, Ondraya Frick, Allison L. Totura, Virginia Livingston, Donald K. Nichols, David W. Dyer
Publikováno v:
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 26, Iss 12, Pp 2835-2843 (2020)
Emerging Infectious Diseases, Vol 26, Iss 12, Pp 2835-2843 (2020)
Emerging highly pathogenic coronaviruses (CoV) are a global public health threat due to the potential for person-to-person transmission and higher mortality rates than common seasonal respiratory pathogens. Middle East respiratory syndrome coronaviru
Autor:
Wataru Akahata, Vicki Traina-Dorge, Donald K. Nichols, Gretchen L. Schieber, Yaroslav Tsybovsky, Tyler Stephens, John R. Mascola, Crystal W. Burke, Kevin Carlton, Sung-Youl Ko, Stephen Higgs, Eun Sung Yang, Shelley P. Honnold, Dana L. Vanlandingham, Pamela J. Glass, Yan-Jang S. Huang, Srinivas S. Rao, Ulrich Baxa, Gary J. Nabel, Luis DaSilva, Wing-Pui Kong, Chad J. Roy
Publikováno v:
Science Translational Medicine. 11
Western, Eastern, and Venezuelan equine encephalitis viruses (WEEV, EEEV, and VEEV, respectively) are important mosquito-borne agents that pose public health and bioterrorism threats. Despite considerable advances in understanding alphavirus replicat
Autor:
Jay W. Hooper, Alicia M. Moreau, Sharon P. Daye, Joshua D. Shamblin, Casey C. Perley, Kelly S. Wetzel, Donald K. Nichols, Rebecca L. Brocato, Steven A. Kwilas
Publikováno v:
PLOS ONE
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216700 (2019)
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216700 (2019)
Hantaan virus (HTNV) and Puumala virus (PUUV) are rodent-borne hantaviruses that are the primary causes of hemorrhagic fever with renal syndrome (HFRS) in Europe and Asia. The development of well characterized animal models of HTNV and PUUV infection
Autor:
Stuart T. Nichol, Brett P. Eaton, Nate Larson, Ginger Donnelly, Mike Flint, Robert Jordan, Douglas L. Mayers, Michel Perron, Yeojin Park, Dustin Siegel, Lydia Wolfe, Veronica Soloveva, Edward Doerffler, William A. Lee, Donald K. Nichols, Dima N. Gharaibeh, Elizabeth C. Grimes, Laura Gomba, Darius Babusis, Travis K. Warren, Kwon Soo Chun, Tomas Cihlar, Queenie Wang, Adrian S. Ray, Kirsten M. Stray, Bruce Ross, Elyse R. Nagle, Kelly S. Stuthman, Lisa S. Welch, Rachel Fearns, Jonathan E. Nuss, Willard Lew, Jeffrey R. Kugelman, Molly R. Braun, Roy Bannister, Richard L. Mackman, Pamela Wong, Christina F. Spiropoulou, Joy Y. Feng, Hui Hon Chung, Ona Barauskas, Sean Neville, Jay Wells, Robert G. Strickley, Catherine L. Wilhelmsen, S. Swaminathan, Iva Trancheva, Nicole L. Garza, Cary Retterer, Michael K. Lo, Sean A. Van Tongeren, Gustavo Palacios, Laura K. McMullan, Amy C. Shurtleff, Lijun Zhang, Michael O. Clarke, Yili Xu, Sina Bavari, Tara Kenny, Ernest Carra, Rouzbeh Zamani, Shan Shan Chen
Publikováno v:
Nature
The most recent Ebola virus outbreak in West Africa, which was unprecedented in the number of cases and fatalities, geographic distribution, and number of nations affected, highlights the need for safe, effective, and readily available antiviral agen
Autor:
John M. Dye, Samantha E. Zak, James F. Barth, Andrew S. Herbert, Majidat A. Muhammad, Kurt Kamrud, Ana I. Kuehne, Mary Kate Hart, Ramon A. Ortiz, Gene G. Olinger, Jennifer L. Groebner, Donald K. Nichols, William D. Pratt, Jonathan F. Smith, John S. Lee, Spencer W. Stonier, Max Custer, Russell R. Bakken, Laura I. Prugar
Publikováno v:
Journal of Virology. 87:4952-4964
There are no vaccines or therapeutics currently approved for the prevention or treatment of ebolavirus infection. Previously, a replicon vaccine based on Venezuelan equine encephalitis virus (VEEV) demonstrated protective efficacy against Marburg vir