Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Donald K. Ingram"'
Autor:
Julie A. Mattison, Ricki J. Colman, T. Mark Beasley, David B. Allison, Joseph W. Kemnitz, George S. Roth, Donald K. Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M. Anderson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Caloric restriction (CR) delays ageing of model organisms, but whether it works in nonhuman primates has been controversial. Here, the authors pool and reanalyse data from two long-running CR primate studies, concluding that moderate CR indeed improv
Externí odkaz:
https://doaj.org/article/3a76c66b68f7460284eef313ff046d21
Autor:
Christy L. White, Paul J. Pistell, Megan N. Purpera, Sunita Gupta, Sun-Ok Fernandez-Kim, Taylor L. Hise, Jeffrey N. Keller, Donald K. Ingram, Christopher D. Morrison, Annadora J. Bruce-Keller
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 1, Pp 3-13 (2009)
This study was undertaken to investigate the effects of prenatal and postnatal exposure to high fat diet on the brain. Female rats were divided into high fat diet (HFD) and control diet (CD) groups 4 weeks prior to breeding and throughout gestation a
Externí odkaz:
https://doaj.org/article/9d01f25f260b4e468702bb723ef49609
Autor:
Luke B. Ravi, Suresh Poosala, Dongchoon Ahn, Francis J. Chrest, Edward L. Spangler, Rajadas Jayakumar, Enika Nagababu, Joy G. Mohanty, Mark Talan, Donald K. Ingram, Joseph M. Rifkind
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 28-37 (2005)
Vascular amyloidosis in Alzheimer's disease (AD) results in the exposure of red blood cells to β-amyloid fibrils (Aβ). The potential in vivo ramifications of this exposure have been investigated by injecting Aβ1–40 alone or Aβ-bound mouse red b
Externí odkaz:
https://doaj.org/article/306fa1039dd0455dbd0e1cb2d0f9cdde
Autor:
Michael F. Salvatore, Ella A. Kasanga, D. Parker Kelley, Katy E. Venable, Tamara R. McInnis, Mark A. Cantu, Jennifer Terrebonne, Kathryn Lanza, Samantha M. Meadows, Ashley Centner, Christopher Bishop, Donald K. Ingram
Publikováno v:
GeroScience
Identifying neurobiological mechanisms of aging-related parkinsonism, and lifestyle interventions that mitigate them, remain critical knowledge gaps. No aging study, from rodent to human, has reported loss of any dopamine (DA) signaling marker near t
Autor:
Paul J. Pistell, Tadanobu Utsuki, Joseph Francis, Philip J. Ebenezer, Jennifer Terrebonne, George S. Roth, Donald K. Ingram
Publikováno v:
Nutrients
Nutrients, Vol 14, Iss 155, p 155 (2022)
Nutrients; Volume 14; Issue 1; Pages: 155
Nutrients, Vol 14, Iss 155, p 155 (2022)
Nutrients; Volume 14; Issue 1; Pages: 155
Beginning at 16 weeks of age and continuing for 44 weeks, male C57BL/6J were fed either a control (CON) diet; a high-fat (HF) diet (60% unsaturated); or the HF diet containing an extract of unripe avocados (AvX) enriched in the 7-carbon sugar mannohe
Publikováno v:
Image Analysis and Stereology, Vol 24, Iss 1, Pp 41-49 (2011)
State-of-the-art computerized stereology systems combine high-resolution video microscopy and hardwaresoftware integration with stereological methods to assist users in quantifying multidimensional parameters of importance to biomedical research, inc
Externí odkaz:
https://doaj.org/article/c13d6f4f2a934633950940f9c44b44ee
Autor:
Paul J. Pistell, George S. Roth, Michael G. Hayek, Donald K. Ingram, Yongmei Yu, Gary Mitchell Davenport, Zhong Q Wang, Stefan Patrick Massimino
Publikováno v:
Journal of agricultural and food chemistry. 69(26)
Increased consumer interest in the avocado (Persea americana or Persea gratissima) has been attributed to established health benefits of this fruit associated with a wide range of ingredients. In search of effective calorie restriction mimetics (CRM)
Autor:
Donald K. Ingram, George S. Roth
Publikováno v:
GeroScience
Calorie restriction mimetics encompass a growing research field directed toward developing treatments that mimic the anti-aging effects of long-term calorie restriction without requiring a change in eating habits. A wide range of approaches have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625389c82463080a5325bdd7674acf72
https://europepmc.org/articles/PMC8190254/
https://europepmc.org/articles/PMC8190254/
Autor:
Douglas L. Rosene, Julie A. Mattison, R L Woltjer, Henryk F. Urbanski, Donald K. Ingram, G A Stonebarger, Kelli L. Vaughan, Steven G. Kohama, P L Schultz, S M Calderazzo, J A Siedeman
Publikováno v:
GeroScience
As human lifespan increases and the population ages, diseases of aging such as Alzheimer’s disease (AD) are a major cause for concern. Although calorie restriction (CR) as an intervention has been shown to increase healthspan in many species, few s
Autor:
Carrie M Elks, Scott D Reed, Nithya Mariappan, Barbara Shukitt-Hale, James A Joseph, Donald K Ingram, Joseph Francis
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24028 (2011)
OBJECTIVE AND BACKGROUND:To assess renoprotective effects of a blueberry-enriched diet in a rat model of hypertension. Oxidative stress (OS) appears to be involved in the development of hypertension and related renal injury. Pharmacological antioxida
Externí odkaz:
https://doaj.org/article/45c13e7ccca6473a910110b5ae3c2216