Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Donald Joseph-Phillip Pinto"'
Autor:
Stephen W. Wright, Douglas Guy Batt, M. A. Pratta, Joseph J. Petraitis, Ronald L. Magolda, E. C. Arner, Susan R. Sherk, John V. Giannaras, Donald Joseph-Phillip Pinto, Orwat Michael James, Ronald L. Corbett, Bruce Freimark, Jean M. Williams, Susan V. Di Meo, Herman F. Stampfli
Publikováno v:
Bioorganic & Medicinal Chemistry. 3:227-234
A series of 2-(arylmethyl)pyridoisothiazolones is reported that inhibit the IL-1 β induced breakdown of bovine nasal septum cartilage in an organ culture assay. The synthesis and preliminary SAR of these compounds are described. These compounds repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5b6f7bd4ce3596c642a1014e6fbbe1
https://doi.org/10.1016/0968-0896(95)00018-c
https://doi.org/10.1016/0968-0896(95)00018-c
Autor:
William Henry Miller, M. A. Pratta, E. C. Arner, Robert J. McHugh, Donald Joseph-Phillip Pinto, Ronald L. Magolda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:843-846
Several aryl-fused isothiazoloquinolinones were prepared and were found to inhibit IL-1β induced degradation of bovine nasal cartilage in an organ culture assay. These compounds, derived conceptually from the benzisothiazolone ring system, represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94e50d33476fe37d56df61cc83ecfe2d
https://doi.org/10.1016/s0960-894x(01)80860-x
https://doi.org/10.1016/s0960-894x(01)80860-x
Autor:
Alicia M. Green, Stephen W. Wright, Susan R. Sherk, Ronald L. Magolda, Donald Joseph-Phillip Pinto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1079-1084
Vinylogous hydroxamic acids were prepared as inhibitors of 5-lipoxygenase. The synthesis and preliminary SAR of these relatively unexplored compounds are described. These compounds are potent 5-lipoxygenase inhibitors which do not inhibit other enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2d69d56aed0acc601e2fd0a1b8bb4de
https://doi.org/10.1016/s0960-894x(00)80622-8
https://doi.org/10.1016/s0960-894x(00)80622-8