Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Donald J. Skalitzky"'
Autor:
Ru Zhou, James W. Meador, Peter S. Dragovich, Amy K. Patick, Shella A. Fuhrman, Stephen T. Worland, Donald J. Skalitzky, Clifford E. Ford
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:589-598
The optimization of a series of irreversible human rhinovirus (HRV) 3C protease (3CP) inhibitors is described. These inhibitors are comprised of an l -Leu- l -Phe- l -Gln tripeptide containing an N-terminal amide moiety and a C-terminal ethyl propeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511057898c8e382a80c97a23c18c3673
https://doi.org/10.1016/s0968-0896(99)00005-x
https://doi.org/10.1016/s0968-0896(99)00005-x
Autor:
James A. Morrison, Anna Chiu, Kazuhiro Irie, Michael F. T. Koehler, Jef K. De Brabander, Stephan N. Müller, Masahiro Tanaka, Stephan G. Müller, Andrew J. Carpenter, Cheol-Min Park, Yolanda Martin-Cantalejo, Shiozaki Makoto, Carsten Siedenbiedel, Donald J. Skalitzky, Patrick G. Harran, Paul A. Wender, Juan Miguel Jimenez, Blaise Lippa
Publikováno v:
Pure and Applied Chemistry. 70:539-546
This lecture provides an overview of investigations directed towards understanding the molecular mechanism of protein kinase C (PKC) activation and function. Central to this effort are studies on the total synthesis of phorbol, the first asymmetric s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583e98dbd9f8c81baaae99ce2049b681
https://doi.org/10.1351/pac199870030539
https://doi.org/10.1351/pac199870030539
Publikováno v:
Tetrahedron Letters. 37:8679-8682
A variety of 4-allyl-1,3-dioxanes were prepared and cyclized to give 4-chloro or 4-acetoxy tetrahydropyrans in good yields and with high stereoselectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582f3c56c1b1c921d1c57d3f957c99d0
https://doi.org/10.1016/s0040-4039(96)02008-4
https://doi.org/10.1016/s0040-4039(96)02008-4
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::059d2d78b5f252878bb5fcca1dfb8b23
https://doi.org/10.1002/chin.199204052
https://doi.org/10.1002/chin.199204052
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357f99580356169d87c2a0bd45d89eef
https://doi.org/10.1002/chin.199220303
https://doi.org/10.1002/chin.199220303
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8113ac08984c75f725aa39e9f6774ae2
https://doi.org/10.1002/chin.199540161
https://doi.org/10.1002/chin.199540161
Publikováno v:
ChemInform. 28
A variety of 4-allyl-1,3-dioxanes were prepared and cyclized to give 4-chloro or 4-acetoxy tetrahydropyrans in good yields and with high stereoselectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5350d023cd498a9fe2c28a4500577aee
https://doi.org/10.1002/chin.199711113
https://doi.org/10.1002/chin.199711113
Publikováno v:
ChemInform. 31
Configurationally defined α-alkoxylithium reagents were prepared by reductive lithiation of 4-(phenylthio)-1,3-dioxanes. A new and more general synthesis of 4-(phenylthio)-1,3-dioxanes has been developed on the basis of the reduction and in situ ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a4b0f4404f39f5954e5b0adc4ef290
https://doi.org/10.1002/chin.200003035
https://doi.org/10.1002/chin.200003035
Publikováno v:
The Journal of Organic Chemistry. 57:4336-4339
Phenylthio acetals 3 are easily prepared from β-hydroxy aldehydes and can be reduced to anti alkyllithiums 7 and subsequently equilibrated to syn alkyllithiums 9 with excellent stereoselectivity and in good overall yield. A pratical preparation of 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb852315839e51fe6d55d32b0f74938
https://doi.org/10.1021/jo00042a005
https://doi.org/10.1021/jo00042a005
Publikováno v:
Journal of the American Chemical Society. 114:671-677
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cc5b485a1787e96063bb08d62be572d
https://doi.org/10.1021/ja00028a039
https://doi.org/10.1021/ja00028a039