Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Donald J. Nachreiner"'
Publikováno v:
Journal of Toxicology, Vol 2011 (2011)
Ethylene oxide was tested on groups of rats for either 4-hour or 1-hour inhalation exposure, followed by 14 days of observation. Groups of five Sprague-Dawley rats/sex were exposed, and clinical signs and mortality were recorded. Clinical signs noted
Externí odkaz:
https://doaj.org/article/8a13e35c3e6249c39c2422af9724b571
Autor:
Irvin M. Pritts, Darol E. Dodd, Elton R. Homan, Dennis R. Klonne, Catherine M. Troup, Edward H. Fowler, Bryan Ballantyne, Donald J. Nachreiner
Publikováno v:
Toxicological Sciences. 9:512-521
Dimethylethanolamine (DMEA) is a volatile, water-soluble amine that has applications in the chemical and pharmaceutical industries. These studies evaluated the acute and subchronic inhalation toxicity of DMEA. Acute (4-hr) exposures of Wistar rats to
Publikováno v:
Drug and chemical toxicology. 11(1)
Para-tertiary butylphenol [(PTBP); the Union Carbide Corporation trademark for this chemical is UCAR Butylphenol 4-T Flake] has applications as a raw material in the manufacture of resins and also as an industrial intermediate. Acute peroral LD50 val
Publikováno v:
Human toxicology. 8(3)
1 The LC50 values for acrolein (AC) vapour to Sprague-Dawley rats (combined sexes) were determined to be 26 ppm (1 h) and 8.3 ppm (4 h). Signs of severe irritancy were present, and death was due to lung injury. 2 Exposure of rats to a 2-methoxy-3,4-d
Publikováno v:
Drug and chemical toxicology. 9(2)
2,4-Pentanedione was found to have acute peroral LD50 values (with 95% confidence limits) in the rat of 0.78 (0.66-0.91) ml/kg for males and 0.59 (0.51-0.70) ml/kg for females, and acute percutaneous LD50 values by 24 hr occluded contact on the rabbi
Publikováno v:
Drug and chemical toxicology. 8(1-2)
N-Benzyl-N,N-dimethylamine (BDMA), a polyester foam catalyst, was determined to have LD50 values of 0.65 (0.48-0.88) ml/kg perorally in the rat, and 1.66 (1.35-2.04) ml/kg by 24-hr occluded dermal contact in rabbits. The Lt50 for saturated vapor atmo
Autor:
Darol E. Dodd, Bryan Ballantyne, Irvin M. Pritts, Dennis R. Klonne, Catherine M. Troup, Donald J. Nachreiner
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 8(2)
At ambient conditions, the low vapor pressure of ethylene glycol monohexyl ether (EGHE) allows for a maximum vapor concentration of approximately 85 ppm. In an acute inhalation study on Wistar albino rats, a 4-hr exposure to 83 ppm EGHE produced no c