Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Donald Hamelberg"'
Autor:
Xin-Qiu Yao, Donald Hamelberg
Publikováno v:
JACS Au, Vol 4, Iss 2, Pp 837-846 (2024)
Externí odkaz:
https://doaj.org/article/9848dff11f98491bb757f1bb0038530d
Autor:
Arghya Barman, Donald Hamelberg
Publikováno v:
ACS Omega, Vol 1, Iss 5, Pp 837-842 (2016)
Externí odkaz:
https://doaj.org/article/fe3bc7ee9530496d99d6f9ed61ccaaa6
Autor:
Chen Zhang, Nagaraju Mulpuri, Fadil M Hannan, M Andrew Nesbit, Rajesh V Thakker, Donald Hamelberg, Edward M Brown, Jenny J Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113622 (2014)
The Ca(2+)-sensing receptor (CaSR) regulates Ca(2+) homeostasis in the body by monitoring extracellular levels of Ca(2+) ([Ca(2+)]o) and amino acids. Mutations at the hinge region of the N-terminal Venus flytrap domain (VFTD) produce either receptor
Externí odkaz:
https://doaj.org/article/4d37cc14efa74f3ba3cd8251071ff027
Publikováno v:
The Journal of Physical Chemistry B. 127:3139-3150
Publikováno v:
Biochemistry. 62:1070-1081
Publikováno v:
The Journal of Physical Chemistry B. 126:10844-10853
Mitochondria are the powerhouse of a cell, whose disruption due to mitochondrial pore opening can cause cell death, leading to necrosis and many other diseases. The peptidyl-prolyl
Publikováno v:
Medicinal Research Reviews. 43:293-318
The centrosome in animal cells is instrumental in spindle pole formation, nucleation, proper alignment of microtubules during cell division, and distribution of chromosomes in each daughter cell. Centrosome amplification involving structural and nume
Residue–Residue Contact Changes during Functional Processes Define Allosteric Communication Pathways
Autor:
Xin-Qiu Yao, Donald Hamelberg
Publikováno v:
Journal of Chemical Theory and Computation. 18:1173-1187
Allosteric regulation plays a central role in orchestrating diverse cellular processes. A prerequisite for allostery is a flexible biomolecule within which two distal sites can communicate via concerted or sequential conformational changes. We introd
Autor:
Xin-Qiu Yao, Ning Fang, Angela M. Mabb, Zheng Zachory Wei, Daniel Ouedraogo, Giovanni Gadda, You Zhuo, Ken Berglund, Bin Dong, Cheyenne McBean, Xiaonan Deng, Shan Ping Yu, Jenny J. Yang, Samer Gozem, Mohammad A Ghane, Ling Wei, Donald Hamelberg
Publikováno v:
Angewandte Chemie. 133:23477-23486
Multi-scale calcium (Ca2+ ) dynamics, exhibiting wide-ranging temporal kinetics, constitutes a ubiquitous mode of signal transduction. We report a novel endoplasmic-reticulum (ER)-targeted Ca2+ indicator, R-CatchER, which showed superior kinetics in