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of 69
pro vyhledávání: '"Donald H. Atha"'
Autor:
Donald H. Atha, Vytas Reipa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5427 (2023)
As the potential applications of DNA diagnostics continue to expand, there is a need for improved methods and standards for DNA analysis. This report describes several methods that could be considered for the production of reference materials for the
Externí odkaz:
https://doaj.org/article/a956c5e9fcbb4faaad8fe0f7de870979
Publikováno v:
Journal of Nucleic Acids, Vol 2022 (2022)
Application of DNA damage diagnostic tests is rapidly growing, in particular for ovarian, prostate, and skin cancers; environmental monitoring; chronic and degenerative diseases; and male infertility. Such tests suffer from significant variability am
Externí odkaz:
https://doaj.org/article/dc73682a252a4574b5c318a54b009fff
Publikováno v:
Journal of Nucleic Acids, Vol 2020 (2020)
Reference materials are needed to quantify the level of DNA damage in cells, to assess sources of measurement variability and to compare results from different laboratories. The comet assay (single cell gel electrophoresis) is a widely used method to
Externí odkaz:
https://doaj.org/article/8a21cc771699430d80e03f75f836bb87
Publikováno v:
Journal of Nucleic Acids, Vol 2020 (2020)
To evaluate methods for analysis of genotoxic effects on mammalian cell lines, we tested the effect of three common genotoxic agents on Chinese hamster ovary (CHO) cells by single-cell gel electrophoresis (comet assay) and gas chromatography-tandem m
Externí odkaz:
https://doaj.org/article/f52cbe19d05d4856ba1c417f4f8f0ec7
Autor:
Donald H. Atha, Amber Nagy, Andrea Steinbrück, Allison M. Dennis, Jennifer A. Hollingsworth, Varsha Dua, Rashi Iyer, Bryant C. Nelson
Publikováno v:
Journal of Nanobiotechnology, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background When evaluating the toxicity of engineered nanomaterials (ENMS) it is important to use multiple bioassays based on different mechanisms of action. In this regard we evaluated the use of gene expression and common cytotoxicity meas
Externí odkaz:
https://doaj.org/article/55537b5d54e440e5bbdbadb2fc15a891
Autor:
Vytas Reipa, Donald H. Atha
Publikováno v:
Challenges, Vol 9, Iss 1, p 17 (2018)
With the rapid development of new nanomaterials, it was recognized early that together with their beneficial properties, nanomaterials may pose a risk to human health and the environment. Evidence has accumulated over the last twenty years in support
Externí odkaz:
https://doaj.org/article/f55bbf6624924574a9c8a6cac3477764
Publikováno v:
Journal of Nucleic Acids, Vol 2020 (2020)
Journal of Nucleic Acids
Journal of Nucleic Acids
To evaluate methods for analysis of genotoxic effects on mammalian cell lines, we tested the effect of three common genotoxic agents on Chinese hamster ovary (CHO) cells by single-cell gel electrophoresis (comet assay) and gas chromatography-tandem m
Publikováno v:
Journal of Nucleic Acids
Journal of Nucleic Acids, Vol 2020 (2020)
Journal of Nucleic Acids, Vol 2020 (2020)
Reference materials are needed to quantify the level of DNA damage in cells, to assess sources of measurement variability and to compare results from different laboratories. The comet assay (single cell gel electrophoresis) is a widely used method to
Autor:
Amber Nagy, Donald H. Atha, Andrea Steinbrück, Varsha Dua, Allison M. Dennis, Jennifer A. Hollingsworth, Bryant C. Nelson, Rashi Iyer
Publikováno v:
Journal of Nanobiotechnology, Vol 15, Iss 1, Pp 1-9 (2017)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background When evaluating the toxicity of engineered nanomaterials (ENMS) it is important to use multiple bioassays based on different mechanisms of action. In this regard we evaluated the use of gene expression and common cytotoxicity measurements
Autor:
Amber Nagy, Michael H. Stewart, Bin Hu, Cristina Rios Valdez, Rashi Iyer, Donald H. Atha, Andrea Steinbrück, Momchilo Vuyisich, Peter C. Stark, Jennifer A. Hollingsworth, Bryant C. Nelson
Publikováno v:
ACS Nano. 7:8397-8411
Quantum dots (QDs) are semiconductor nanocrystals exhibiting unique optical properties that can be exploited for many practical applications ranging from photovoltaics to biomedical imaging and drug delivery. A significant number of studies have allu