Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Donald G. Buerk"'
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Nitric oxide (NO) generated from nitrite through nitrite reductase activity in red blood cells has been proposed to play a major role in hypoxic vasodilation. However, we have previously predicted from mathematical modeling that much more NO can be d
Externí odkaz:
https://doaj.org/article/2678ce86c74046f0b24a9528f07f9b24
Publikováno v:
Nitric Oxide
Endothelial dysfunction, characterised by impaired nitric oxide (NO) bioavailability, arises in response to a variety of cardiovascular risk factors and precedes atherosclerosis. NO is produced by tight regulation of endothelial nitric oxide synthase
Publikováno v:
Cellular Signalling. 87:110125
Background Protein Kinase C (PKC) is a promiscuous serine/threonine kinase regulating vasodilatory responses in vascular endothelial cells. Calcium-dependent PKCbeta (PKCβ) and calcium-independent PKCeta (PKCη) have both been implicated in the regu
Publikováno v:
Nitric Oxide. 60:1-9
Nitrite infusion into the bloodstream has been shown to elicit vasodilation and protect against ischemia-reperfusion injury through nitric oxide (NO) release in hypoxic conditions. However, the mechanism by which nitrite-derived NO escapes scavenging
Autor:
Donald G. Buerk, Balam Benítez-Mata, Kelly A. Zaccheo, Kenneth A. Barbee, Dov Jaron, Michelle A. Digman
Publikováno v:
Biophysical Journal. 120:324a
INTRODUCTION: Colocalization of endothelial nitric oxide synthase (eNOS) and capacitative Ca(2+) entry (CCE) channels in microdomains such as cavaeolae in endothelial cells (ECs) has been shown to significantly affect intracellular Ca(2+) dynamics an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ee13df2f410f1fd55b418657b655b2
https://europepmc.org/articles/PMC6166655/
https://europepmc.org/articles/PMC6166655/
Interactions between cardiac myoglobin (Mb), nitrite, and nitric oxide (NO) are vital in regulating O2 storage, transport, and NO homeostasis. Production of NO through the reduction of endogenous myocardial nitrite by deoxygenated myoglobin has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ab332c584804e82825d7575a7c0694
https://europepmc.org/articles/PMC5500307/
https://europepmc.org/articles/PMC5500307/
Autor:
Tenderano T. Muzorewa, Dov Jaron, Allison M. Andrews, Kenneth A. Barbee, Kelly A. Zaccheo, Donald G. Buerk
Publikováno v:
Cellular and molecular bioengineering. 10(1)
Endothelial dysfunction, characterized by decreased production or availability of nitric oxide (NO), is widely believed to be the hallmark of early-stage atherosclerosis. In addition, hypercholesterolemia is considered a major risk factor for develop
Autor:
Elizabeth Anne Browning, Gonder D, Kristine Debolt, Wang H, Hong N, Elena M. Sorokina, Shampa Chatterjee, Patel P, Donald G. Buerk, Aron B. Fisher, Sheldon I. Feinstein, Yu K, De Leon Dd
Publikováno v:
Antioxidants & Redox Signaling. 20:872-886
Aims: We reported earlier that ischemia results in the generation of reactive oxygen species (ROS) via the closure of a KATP channel which causes membrane depolarization and NADPH oxidase 2 (NOX2) activation. This study was undertaken to understand t
Publikováno v:
Nitric oxide : biology and chemistry. 60
Nitrite infusion into the bloodstream has been shown to elicit vasodilation and protect against ischemia-reperfusion injury through nitric oxide (NO) release in hypoxic conditions. However, the mechanism by which nitrite-derived NO escapes scavenging