Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Donald G Therasse"'
Autor:
Luann E. Van Campen, Tatjana Poplazarova, Donald G. Therasse, Michael Turik, The Biopharmaceutical Bioethics Working Group
Publikováno v:
BMC Medical Ethics, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background The biopharmaceutical industry operates at the intersection of life sciences, clinical research, clinical care, public health, and business, which presents distinct operational and ethical challenges. This setting merits focused b
Externí odkaz:
https://doaj.org/article/913810bcb58146dabbce4d3ecfcf45fb
Publikováno v:
BMC Medical Ethics, Vol 22, Iss 1, Pp 1-11 (2021)
BMC Medical Ethics
BMC Medical Ethics
BackgroundThe biopharmaceutical industry operates at the intersection of life sciences, clinical research, clinical care, public health, and business, which presents distinct operational and ethical challenges. This setting merits focused bioethics c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bfdf4ebe64697ffc9ebbef47218e8c
https://doaj.org/article/913810bcb58146dabbce4d3ecfcf45fb
https://doaj.org/article/913810bcb58146dabbce4d3ecfcf45fb
Publikováno v:
Current Medical Research and Opinion. 31:2071-2080
Pharmaceutical human biomedical research is a multi-dimensional endeavor that requires collaboration among many parties, including those who sponsor, conduct, participate in, or stand to benefit from the research. Human subjects' protections have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e572f61050fa4f8f5017aeb175b603d0
https://doi.org/10.1185/03007995.2015.1087986
https://doi.org/10.1185/03007995.2015.1087986
Publikováno v:
Ajob Empirical Bioethics
Background: Bioethics consultations are conducted in varied settings, including hospitals, universities, and other research institutions, but there is sparse information about bioethics consultations conducted in corporate settings such as pharmaceut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83d347efa0c1da47a94c3965a0e1ec1
https://doi.org/10.1080/23294515.2014.957363
https://doi.org/10.1080/23294515.2014.957363
Publikováno v:
Current medical research and opinion. 31(11)
Current ethics and good clinical practice guidelines address various aspects of pharmaceutical research and development, but do not comprehensively address the bioethical responsibilities of sponsors. To fill this void, in 2010 Eli Lilly and Company
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54481c9809b8f5cfd33e2c5a2a365a59
https://pubmed.ncbi.nlm.nih.gov/26325585
https://pubmed.ncbi.nlm.nih.gov/26325585
Autor:
Robert L Davidson, Karl A. DeSante, Leonard J Quadracci, Benito J. Cerimele, Barbara L. Hatcher, Diane S Farlow, Donald G Therasse
Publikováno v:
Clinical Pharmacology and Therapeutics. 54:311-316
Loracarbef, the first carbacephem antibiotic to undergo clinical development, is excreted primarily unchanged in the urine (>90%). Data analyzed from subjects with various degrees of renal dysfunction who were given single oral doses of loracarbef in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaec57f1516a68ffaa13d9841ee53ad7
https://doi.org/10.1038/clpt.1993.152
https://doi.org/10.1038/clpt.1993.152
Autor:
Donald G. Therasse
Publikováno v:
The Pediatric Infectious Disease Journal. 11:S2
The efficacy and safety of the antibiotic loracarbef have been demonstrated in a series of 22 clinical trials involving over 9,000 patients. The data compiled from these trials indicate that loracarbef is well tolerated by the majority of patients, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718eb3d6f35da38d45f0a85ffeb12607
https://doi.org/10.1097/00006454-199208001-00010
https://doi.org/10.1097/00006454-199208001-00010
Autor:
Mary B. Ross, Burgunda W. Volger, Helen R. Brunetti, Donald G. Therasse, David D. Baumgartner
Publikováno v:
American Journal of Health-System Pharmacy. 45:1540-1544
Compliance with a policy for use of antimicrobial agents that requires both oral approval from the infectious diseases service and completion of a restricted antimicrobial agent use form was evaluated in a 950-bed teaching hospital. The charts of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af2b0322d4782f11ef0b3d59fa31749
https://doi.org/10.1093/ajhp/45.7.1540
https://doi.org/10.1093/ajhp/45.7.1540