Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Donald G Payan"'
Autor:
Wei Li, Mark D Claypool, Annabelle M Friera, John McLaughlin, Kristen A Baltgalvis, Ira J Smith, Taisei Kinoshita, Kathy White, Wayne Lang, Guillermo Godinez, Donald G Payan, Todd M Kinsella
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94032 (2014)
Numerous human diseases can lead to atrophy of skeletal muscle, and loss of this tissue has been correlated with increased mortality and morbidity rates. Clinically addressing muscle atrophy remains an unmet medical need, and the development of precl
Externí odkaz:
https://doaj.org/article/408c765604924646b1fef41e484a25ef
Autor:
Yonchu Jenkins, Tian-Qiang Sun, Vadim Markovtsov, Marc Foretz, Wei Li, Henry Nguyen, Yingwu Li, Alison Pan, Gerald Uy, Lisa Gross, Kristen Baltgalvis, Stephanie L Yung, Tarikere Gururaja, Taisei Kinoshita, Alexander Owyang, Ira J Smith, Kelly McCaughey, Kathy White, Guillermo Godinez, Raniel Alcantara, Carmen Choy, Hong Ren, Rachel Basile, David J Sweeny, Xiang Xu, Sarkiz D Issakani, David C Carroll, Dane A Goff, Simon J Shaw, Rajinder Singh, Laszlo G Boros, Marc-André Laplante, Bruno Marcotte, Rita Kohen, Benoit Viollet, André Marette, Donald G Payan, Todd M Kinsella, Yasumichi Hitoshi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81870 (2013)
Modulation of mitochondrial function through inhibiting respiratory complex I activates a key sensor of cellular energy status, the 5'-AMP-activated protein kinase (AMPK). Activation of AMPK results in the mobilization of nutrient uptake and cataboli
Externí odkaz:
https://doaj.org/article/9f3bbe0f39b0498d932c53dbf27c0985
Autor:
Yan Chen, Hui Li, Rose Yen, Thilo J. Heckrodt, Darren McMurtrie, Rajinder Singh, Vanessa Taylor, Esteban S. Masuda, Gary Park, Donald G. Payan
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1805-1811
Janus kinases (JAK) play a critical role in JAK/signal transducer and activator of transcription (STAT) signaling pathways that mediate immune response and cell growth. From high-throughput screening (HTS) hit to lead optimization, a series of pyrimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27df57db1654576746fa239941c9de3
https://doi.org/10.1021/acsmedchemlett.2c00411
https://doi.org/10.1021/acsmedchemlett.2c00411
Autor:
Yasumichi Hitoshi, Donald G. Payan, Rajinder Singh, Dane Goff, Polly Pine, Ralf Brandt, Joanne Chua, Ayodele Apatira, Pingyu Ding, Jing Zhang, Thilo J. Heckrodt, Jiaxin Yu, Allan Torneros, Matt Duan, Weiqun Li, Betty Chang, Yuanming Hu, Christian Franci, Alison Pan, Sacha J. Holland
Supplementary Figure 4 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965b50270ddfffa8a87cf940ea87bd66
https://doi.org/10.1158/0008-5472.22386020.v1
https://doi.org/10.1158/0008-5472.22386020.v1
Autor:
Yasumichi Hitoshi, Donald G. Payan, Rajinder Singh, Dane Goff, Polly Pine, Ralf Brandt, Joanne Chua, Ayodele Apatira, Pingyu Ding, Jing Zhang, Thilo J. Heckrodt, Jiaxin Yu, Allan Torneros, Matt Duan, Weiqun Li, Betty Chang, Yuanming Hu, Christian Franci, Alison Pan, Sacha J. Holland
Supplementary Figure 3 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb03760ccf4434d83f44ee4388c7a9d
https://doi.org/10.1158/0008-5472.22386023
https://doi.org/10.1158/0008-5472.22386023
Autor:
James B. Lorens, Donald G. Payan, Jacques E. Nör, Jakob Bogenberger, Yasumichi Hitoshi, Weiduan Xu, Simon Yu, Mary R. Shen, Joe Lasaga, Stephen Wong, George Yam, Erlina S. Pali, Susan E. Swift, John McLaughlin, Robert E. Atchison, Annabelle M. Friera, Emily W. Chan, Christian Franci, Mark J. Powell, Sacha J. Holland
Supplementary Figures 1-4, Table 1 from Multiple Roles for the Receptor Tyrosine Kinase Axl in Tumor Formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d92204e1842064f0c02ff63011bf82e
https://doi.org/10.1158/0008-5472.22364826
https://doi.org/10.1158/0008-5472.22364826
Autor:
Yasumichi Hitoshi, Donald G. Payan, Rajinder Singh, Dane Goff, Polly Pine, Ralf Brandt, Joanne Chua, Ayodele Apatira, Pingyu Ding, Jing Zhang, Thilo J. Heckrodt, Jiaxin Yu, Allan Torneros, Matt Duan, Weiqun Li, Betty Chang, Yuanming Hu, Christian Franci, Alison Pan, Sacha J. Holland
Supplementary Figure 6 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276191da89619af06920c760a6fcd007
https://doi.org/10.1158/0008-5472.22386014
https://doi.org/10.1158/0008-5472.22386014
Autor:
Yasumichi Hitoshi, Donald G. Payan, Rajinder Singh, Dane Goff, Polly Pine, Ralf Brandt, Joanne Chua, Ayodele Apatira, Pingyu Ding, Jing Zhang, Thilo J. Heckrodt, Jiaxin Yu, Allan Torneros, Matt Duan, Weiqun Li, Betty Chang, Yuanming Hu, Christian Franci, Alison Pan, Sacha J. Holland
Supplementary Figure 1 A-C from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efc270641a6364fe569b8893b546b33
https://doi.org/10.1158/0008-5472.22386032.v1
https://doi.org/10.1158/0008-5472.22386032.v1
Autor:
Yasumichi Hitoshi, Donald G. Payan, Rajinder Singh, Dane Goff, Polly Pine, Ralf Brandt, Joanne Chua, Ayodele Apatira, Pingyu Ding, Jing Zhang, Thilo J. Heckrodt, Jiaxin Yu, Allan Torneros, Matt Duan, Weiqun Li, Betty Chang, Yuanming Hu, Christian Franci, Alison Pan, Sacha J. Holland
Supplementary Tables 1-3 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43829ee11294ace564abb1428fedcef2
https://doi.org/10.1158/0008-5472.22386005
https://doi.org/10.1158/0008-5472.22386005
Autor:
James B. Lorens, Donald G. Payan, Jacques E. Nör, Jakob Bogenberger, Yasumichi Hitoshi, Weiduan Xu, Simon Yu, Mary R. Shen, Joe Lasaga, Stephen Wong, George Yam, Erlina S. Pali, Susan E. Swift, John McLaughlin, Robert E. Atchison, Annabelle M. Friera, Emily W. Chan, Christian Franci, Mark J. Powell, Sacha J. Holland
Supplementary Figure and Table Legends from Multiple Roles for the Receptor Tyrosine Kinase Axl in Tumor Formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3126d3ec9c443998809237be833c029e
https://doi.org/10.1158/0008-5472.22364829
https://doi.org/10.1158/0008-5472.22364829