Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Donald Franklin"'
Autor:
Patricia K. Riggs, Albert M. Anderson, Bin Tang, Leah H. Rubin, Susan Morgello, Christina M. Marra, Benjamin B. Gelman, David B. Clifford, Donald Franklin, Robert K. Heaton, Ronald J. Ellis, Christine Fennema-Notestine, Scott L. Letendre
Publikováno v:
Viruses, Vol 15, Iss 12, p 2410 (2023)
Structural brain abnormalities, including those in white matter (WM), remain common in people with HIV (PWH). Their pathogenesis is uncertain and may reflect multiple etiologies. Oxidative stress is associated with inflammation, HIV, and its comorbid
Externí odkaz:
https://doaj.org/article/674144d9abd54ab9bbe9c396f0f14767
Autor:
Bryn C. Taylor, Mohammadsobhan Sheikh Andalibi, Stephen Wandro, Kelly C. Weldon, Gregory D. Sepich-Poore, Carolina S. Carpenter, Serena Fraraccio, Donald Franklin, Jennifer E. Iudicello, Scott Letendre, Sara Gianella, Igor Grant, Ronald J. Ellis, Robert K. Heaton, Rob Knight, Austin D. Swafford
Publikováno v:
Microorganisms, Vol 11, Iss 4, p 1022 (2023)
Inter-individual differences in the gut microbiome are linked to alterations in inflammation and blood–brain barrier permeability, which may increase the risk of depression in people with HIV (PWH). The microbiome profile of blood, which is conside
Externí odkaz:
https://doaj.org/article/cc970b3572ef4724bbfa294fb75ae9c1
Autor:
Bryn C. Taylor, Kelly C. Weldon, Ronald J. Ellis, Donald Franklin, Tobin Groth, Emily C. Gentry, Anupriya Tripathi, Daniel McDonald, Gregory Humphrey, MacKenzie Bryant, Julia Toronczak, Tara Schwartz, Michelli F. Oliveira, Robert Heaton, Igor Grant, Sara Gianella, Scott Letendre, Austin Swafford, Pieter C. Dorrestein, Rob Knight
Publikováno v:
mSystems, Vol 5, Iss 5 (2020)
ABSTRACT Depression is influenced by the structure, diversity, and composition of the gut microbiome. Although depression has been described previously in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) monoinfections, and to a lesser
Externí odkaz:
https://doaj.org/article/4d000583e1cf4e279932e95eba1e0176
Autor:
Bryn C. Taylor, Kelly C. Weldon, Ronald J. Ellis, Donald Franklin, Daniel McDonald, Gregory Humphrey, MacKenzie Bryant, Julia Toronczak, Tara Schwartz, Jennifer Iudicello, Robert Heaton, Igor Grant, Sara Gianella, Scott Letendre, Austin Swafford, Pieter C. Dorrestein, Rob Knight
Publikováno v:
mSystems, Vol 5, Iss 5 (2020)
ABSTRACT Alterations in the gut microbiome are associated with neurocognition and related disorders, including in the context of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. However, the connection between the gut microbi
Externí odkaz:
https://doaj.org/article/ed8f9ef1aff14b2c9d980f03832a3c48
Autor:
T. Jordan Walter, Jennifer Iudicello, Debra Rosario Cookson, Donald Franklin, Bin Tang, Jared W. Young, William Perry, Ronald Ellis, Robert K. Heaton, Igor Grant, Arpi Minassian, Scott Letendre, on behalf of the Translational Methamphetamine AIDS Research Center (TMARC)
Publikováno v:
Viruses, Vol 13, Iss 7, p 1287 (2021)
Methamphetamine (METH) use disorder is highly prevalent among people with HIV (PWH) and is a significant public health problem. HIV and METH use are each associated with immune system dysfunction; however, the combined effects on the immune system ar
Externí odkaz:
https://doaj.org/article/119e91f6668e4e0db6e437eab50c5c4a
Autor:
Sanjay R. Mehta, Josué Pérez-Santiago, Todd Hulgan, Tyler R. C. Day, Jill Barnholtz-Sloan, Haley Gittleman, Scott Letendre, Ronald Ellis, Robert Heaton, Stephanie Patton, Jesse D. Suben, Donald Franklin, Debralee Rosario, David B. Clifford, Ann C. Collier, Christina M. Marra, Benjamin B. Gelman, Justin McArthur, Allen McCutchan, Susan Morgello, David Simpson, James Connor, Igor Grant, Asha Kallianpur
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-9 (2017)
Abstract Background Mitochondria are abundant organelles critical for energy metabolism and brain function. Mitochondrial DNA (mtDNA), released during cellular injury and as part of the innate immune response to viral pathogens, contains CpG motifs t
Externí odkaz:
https://doaj.org/article/3f496db26c6e42159c52093e350e5c70
Autor:
David C. Samuels, Asha R. Kallianpur, Ronald J. Ellis, William S. Bush, Scott Letendre, Donald Franklin, Igor Grant, Todd Hulgan
Publikováno v:
Pathogens and Immunity, Vol 1, Iss 2, Pp 330-351 (2017)
Background: Mitochondrial DNA (mtDNA) haplogroups are ancestry-related patterns of single-nucleotide polymorphisms that are associated with differential mitochondrial function in model systems, neurodegenerative diseases in HIV-negative populations,
Externí odkaz:
https://doaj.org/article/e8baafaf97d14acbb488dd41465bdac5
Autor:
Arvid Edén, Thomas D Marcotte, Robert K Heaton, Staffan Nilsson, Henrik Zetterberg, Dietmar Fuchs, Donald Franklin, Richard W Price, Igor Grant, Scott L Letendre, Magnus Gisslén
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157160 (2016)
OBJECTIVE:Although milder forms of HIV-associated neurocognitive disorder (HAND) remain prevalent, a correlation to neuronal injury has not been established in patients on antiretroviral therapy (ART). We examined the relationship between mild HAND a
Externí odkaz:
https://doaj.org/article/76e001bde3664fa9963c57abd598f660
Autor:
Asha R Kallianpur, Peilin Jia, Ronald J Ellis, Zhongming Zhao, Cinnamon Bloss, Wanqing Wen, Christina M Marra, Todd Hulgan, David M Simpson, Susan Morgello, Justin C McArthur, David B Clifford, Ann C Collier, Benjamin B Gelman, J Allen McCutchan, Donald Franklin, David C Samuels, Debralee Rosario, Emily Holzinger, Deborah G Murdock, Scott Letendre, Igor Grant, CHARTER Study Group
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103123 (2014)
HIV sensory neuropathy and distal neuropathic pain (DNP) are common, disabling complications associated with combination antiretroviral therapy (cART). We previously associated iron-regulatory genetic polymorphisms with a reduced risk of HIV sensory
Externí odkaz:
https://doaj.org/article/b6001d46828e41dc99eca8d1e55d15d3