Výsledky vyhledávání - "Donald F. Gleason"

The Bicalutamide 150 Mg Early Prostate Cancer Program: Findings of the North American Trial at 7.7-Year Median Followup

Autor: Gregory Bernstein, William A. See, Donald F. Gleason, Clive Morris, Jonathon Armstrong, David G. McLeod, Ira W. Klimberg, Gerald W. Chodak, James E. Montie

Publikováno v: Journal of Urology. 176:75-80

We describe the results of North American Trial 23 of the bicalutamide (Casodex) early prostate cancer program in the context of the overall early prostate cancer program findings.In Trial 23, 3,292 men with T1b-4, N0-Nx (N+ not allowed) M0 prostate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c25ad0865d9f1c41a359932019c7e37
https://doi.org/10.1016/s0022-5347(06)00495-2

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Outcomes for men with clinically nonmetastatic prostate carcinoma managed with radical prostactectomy, external beam radiotherapy, or expectant management

Autor: Horst Zincke, Erik J. Bergstralh, Michael J. Barry, Steven J. Jacobsen, Richard S. Cox, Michael L. Blute, Donald F. Gleason M.D., Malcolm A. Bagshaw, Peter C. Albertsen, Richard G. Middleton

Publikováno v: Cancer. 91:2302-2314

BACKGROUND With a lack of data from randomized trials, the optimal management of men with nonmetastatic prostate carcinoma is controversial. The authors sought to define the outcomes of three common strategies for managing patients with nonmetastatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c8194ea62dfb985bfbff230a8fba035
https://doi.org/10.1002/1097-0142(20010615)91:12<2302::aid-cncr1262>3.0.co

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TRENDS IN GLEASON SCORE FOR PROSTATE CANCER DIAGNOSED BETWEEN 1983 AND 1993

Autor: Noell Stone, Frank D. Gilliland, Linda C. Harlan, Donald F. Gleason, Charles R. Key, William C. Hunt

Publikováno v: The Journal of Urology. :846-850

Purpose: During the 1980s and 1990s the number, incidence rate and proportion of moderately differentiated prostate cancer cases ascertained by population based cancer registries increased substantially. The increase is thought to have resulted from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36971d44f4cd4f2cc5fd9c1ffb98fca5
https://doi.org/10.1097/00005392-200103000-00027

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Codistribution of procathepsin B and mature cathepsin B forms in human prostate tumors detected by confocal and immunofluorescence microscopy

Autor: Pratap K. Reddy, Michael J. Wilson, Akhouri A. Sinha, Bonnie F. Sloane, Donald F. Gleason, Barry J. Quast

Publikováno v: The Anatomical Record. 252:281-289

Cathepsin B (CB) is involved in invasion and metastasis of a variety of solid organ tumors, including human prostate cancer. The tertiary structures of the proenzyme and mature forms of CB are related closely, as revealed by crystallographic studies.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2274119cd5f62f28522b442c2be2b64
https://doi.org/10.1002/(sici)1097-0185(199810)252:2<281::aid-ar14>3.0.co

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Antibody immunoglobulin G (IgG) against human prostatic specific antigen (PSA) as a carrier protein for chemotherapeutic drugs to human prostate tumors: Part 1. A double immunofluorescence analysis

Autor: Onofrea F. Deleon, Akhouri A. Sinha, Donald F. Gleason, James L. Sackrison, Michael J. Wilson

Publikováno v: The Anatomical Record. 245:652-661

Background Adenocarcinoma of the prostate (CaP) is the second highest cause of cancer deaths in U.S. males. Current chemotherapeutic and/or endocrine treatments do not specifically and selectively target tumor cells of prostate cancer and benign pros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c31d0c034b223dbaa0fbb720b2c6292f
https://doi.org/10.1002/(sici)1097-0185(199608)245:4<652::aid-ar5>3.0.co

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Prediction of prognosis in untreated stage A2 prostatic carcinoma

Autor: Yousuf Sharief, Isabell A. Sesterhenn, Jonathan I. Epstein, Robert L. Becker, Alan W. Partin, Donald S. Coffey, Donald F. Gleason, Ulrika V. Mikel, James L. Mohler, F. Kash Mostofi

Publikováno v: Cancer. 69:511-519

Carcinoma is found unexpectedly in approximately 10% or more of the 400,000 prostatectomies performed annually in the United States. Patients with Stage A2 carcinoma die of their disease in only 35% of the cases. To alter the course of disease in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9401bfd76b8fce567650a3a3fe7f0e54
https://doi.org/10.1002/1097-0142(19920115)69:2<511::aid-cncr2820690239>3.0.co

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Is the efficacy of hormonal therapy affected by lymph node status? data from the bicalutamide (Casodex) Early Prostate Cancer program

Autor: Gerald W. Chodak, William A. See, Donald F. Gleason, Karl P.J. Delaere, Kevin Carroll, C.J. Tyrrell, Peter Iversen, James E. Montie, David G. McLeod, D. M. A. Wallace, Ira W. Klimberg, Jan-Erik Johansson, P. E. R. Lundmo, Teuvo L.J. Tammela, Thomas Morris, Manfred P. Wirth

Publikováno v: Urology. 63(5)

Objectives To report an exploratory subgroup analysis assessing the extent to which the overall benefit found in the Early Prostate Cancer program is dependent on lymph node status at randomization. The program is ongoing, and the overall survival da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e987c8b8ab703644ac450910857cf1ec
https://pubmed.ncbi.nlm.nih.gov/15134983

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A phase 3, multicenter, open-label, randomized study of abarelix versus leuprolide acetate in men with prostate cancer

Autor: Donald F. Gleason, David G. McLeod, Kevin M. Tomera, Nick Fotheringham, Marilyn Campion, Norman Zinner, Marc B. Garnick

Publikováno v: Urology. 58(5)

Objectives. To evaluate the levels of testosterone and other hormones in men with prostate cancer treated with abarelix versus leuprolide acetate. Methods. Patients (n = 269) were randomized to receive open-label abarelix 100 mg or leuprolide acetate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf0598954fb9b10ca637c661ac8cdb3
https://pubmed.ncbi.nlm.nih.gov/11711355

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