Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Donald E. Hill"'
Publikováno v:
Developmental Pharmacology and Therapeutics. 14:238-244
We investigated the cardiovascular effects of chlorpromazine (CPZ) during normoxia and during alveolar hypoxia (HYP) in 9 chronically instrumented piglets aged 10-14 days. Each animal was instrumented for measurements of pulmonary and systemic arteri
Publikováno v:
Toxicology and Applied Pharmacology. 73:256-267
A commonly observed result of ethanol administration to experimental animals is a reduction in voluntary dietary intake. The purpose of this investigation was to examine the role of this reduction in the developmental/reproductive toxicity of ethanol
Autor:
Phillip T. Goad, William Slikker, John R. Bailey, Andrew G Hendrickx, Thomas J. Sziszak, Donald E. Hill
Publikováno v:
Developmental Pharmacology and Therapeutics. 6:259-268
Three cynomolgus and 6 rhesus monkeys (106-160 days gestational age) were administered ethanol (0.8-1.5 g/kg i.v.) over a 30-min period. Blood samples were drawn under anesthesia from catheters in the maternal femoral artery, fetal umbilical circulat
Publikováno v:
Pediatric Research. 20:834-837
We investigated the effect of cromolyn sodium, a mast cell stabilizing agent, on the pulmonary vascular response to alveolar hypoxia in six chronically instrumented lambs aged 9 to 11 days. Each lamb was instrumented on day 6 or 7 for measurements of
Autor:
Robert W. Arrington, Richard M. Nestrud, Donald E. Hill, Richard I. Readinger, Pui-Yan Lau, William T. Dungan, Alice G. Beard, J.B. Norton
Publikováno v:
Developmental Pharmacology and Therapeutics. 1:125-136
23 premature infants were placed on a randomized double-blind study to evaluate the effectiveness of indomethacin in closing a patent ductus arteriosus. Infants received 0.2 mg/kg indomethacin or placebo by gavage. In the treatment group, 7 patients
Publikováno v:
Journal of Antimicrobial Chemotherapy. 10:297-301
Ceftizoxime was used to treat 20 infants with suspected bacterial infections. The dosages of ceftizoxime ranged from 140 mg to 300 mg/kg/day with a mean of 232 mg/kg/day. The duration of therapy ranged from 1 to 12 days with a mean of 4.5 days. Satis
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 89:63-70
Man's response to clinical doses of protamine is highly variable. We investigated the influence of circulating heparin in nine swine (mean age 6 weeks, weight 10 kg). Through a sternotomy we implanted an electromagnetic flow probe around the pulmonar
Autor:
Thomas J. Sziszak, William Slikker, Donald E. Hill, Edward D. Helton, George W. Lipe, Glenn D. Newport, John R. Bailey
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 50:811-818
Experiments were performed to describe and compare the transplacental pharmacokinetics of the teratogen and transplacental carcinogen, diethylstilbestrol [4,4'-dihydroxy-alpha,alpha'-diethyl-trans, cis-stilbene (DES)], and the endogenous estrogen, 17
Publikováno v:
Developmental Pharmacology and Therapeutics. 7:319-333
The metabolism of radiolabeled cortisol and triamcinolone acetonide (TAC) was compared in the early, middle, and late gestational age rhesus monkeys. Trace amounts of 14C-cortisol and 10 mg/kg 3H-TAC (Kenalog) were simultaneously administered i.m. to
Publikováno v:
Sleep. 8:254-260
We investigated the effect of sleep on blood pressure control in seven lambs aged 10-14 days. Each lamb had previously been anesthetized and instrumented for measurements of electrocorticogram, electron-oculogram, nuchal and diaphragm electromyograms