Zobrazeno 1 - 10
of 64 726
pro vyhledávání: '"Donald E"'
Autor:
Mary Lorraine Mationg, Archie C. A. Clements, Gail M. Williams, Matthew Kelly, Donald E. Stewart, Catherine A. Gordon, Kinley Wangdi, Sirikachorn Tangkawattana, Apiporn T. Suwannatrai, Vanathom Savathdy, Visal Khieu, Sangduan Wannachart, Suji Yoo O’Connor, Simon Forsyth, Sean Gannon, Peter Odermatt, Donald P. McManus, Somphou Sayasone, Virak Khieu, Banchob Sripa, Darren J. Gray
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Opisthorchis viverrini (OV) and soil-transmitted helminths (STH) are two of the most common helminths contributing to the Neglected Tropical Disease (NTDs) burden in the Lower Mekong Basin. Although mass drug administration is the
Externí odkaz:
https://doaj.org/article/3d45a826c81e40a29dc36f9bdec6db56
Autor:
Ryan Folks, Siny Tsang, Donald E. Brown, Zachary D. Blanks, Nazanin Moradinasab, Michael Mazzeffi, Bhiken I. Naik
Publikováno v:
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background To investigate if intraoperative very short-term variability in blood pressure measured by sample entropy improves discrimination of postoperative acute kidney injury after noncardiac surgery. Methods Adult surgical patients under
Externí odkaz:
https://doaj.org/article/335ee42de0594da4baa1f43ed9dc454f
Autor:
Nicole Lamanna, Constantine S. Tam, Jennifer A. Woyach, Alvaro J. Alencar, M. Lia Palomba, Pier Luigi Zinzani, Ian W. Flinn, Bita Fakhri, Jonathon B. Cohen, Arrin Kontos, Heiko Konig, Amy S. Ruppert, Anindya Chatterjee, Richard Sizelove, Livia Compte, Donald E. Tsai, Wojciech Jurczak
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 929-939 (2024)
Abstract Clinical bleeding events are reported here from 773 patients with B‐cell malignancies receiving pirtobrutinib monotherapy from the phase 1/2 BRUIN study (ClinicalTrials.gov identifier: NCT03740529), either in the presence or absence of ant
Externí odkaz:
https://doaj.org/article/82cd9c8755ab4351873ea8a263b45176
Autor:
Donald E. Casey, Jr., MD, MPH, MBA, Alexander J. Blood, MD, MSc, Stephen D. Persell, MD, MPH, Daniel Pohlman, MD, Jeff D. Williamson, MD, MHS
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 8, Iss 4, Pp 384-395 (2024)
An estimated 45% of adult Americans currently have high blood pressure (HBP). Effective blood pressure (BP) control is essential for preventing major adverse events from cardiovascular and other vascular-related diseases, such as chronic kidney disea
Externí odkaz:
https://doaj.org/article/5e6fe755c98a4d6692ebcddc96c23207
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 7, Pp 1252-1263 (2024)
Abstract Both primary and acquired resistance mechanisms that involve intra‐tumoral cell heterogeneity limit the use of BH3‐mimetics to trigger tumor cell apoptosis. This article proposes a new quantitative systems pharmacology (QSP)‐based meth
Externí odkaz:
https://doaj.org/article/3ab3f61c609f4c81ab5bf9286f895dde
Immune regulatory adjuvant approach to mitigate subcutaneous immunogenicity of monoclonal antibodies
Autor:
Nicole L. Jarvi, Manali Patel, Krithika A. Shetty, Nhan H. Nguyen, Brooke F. Grasperge, Donald E. Mager, Robert M. Straubinger, Sathy V. Balu-Iyer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmunogenicity continues to be a challenge for development and clinical utility of monoclonal antibodies, and there are gaps in our current ability to prevent anti-drug antibody development in a safe and antigen-specific manner.MethodsTo
Externí odkaz:
https://doaj.org/article/7c7da71065644d71b0fbb527a18021ab
Autor:
Katie Stringer Lucero, Donald E. Moore
Publikováno v:
Journal of CME, Vol 13, Iss 1 (2024)
A considerable amount of continuing professional development (CPD) for health professionals is online and voluntary. There is evidence that some CPD activities impact clinical practice outcomes from self-reported and objective, administrative data. S
Externí odkaz:
https://doaj.org/article/b940a9cbaf624c1c9e187c55827251e8
Autor:
Michela Centinari, Donald E. Smith
Publikováno v:
HortTechnology, Vol 34, Iss 6 (2024)
‘Marquette’ is a cold-hardy hybrid grape cultivar that has received increased attention for its use in wine production in the upper midwestern and northeastern United States since it was released in 2006. However, ‘Marquette’ is an early budb
Externí odkaz:
https://doaj.org/article/d96882506dcb49ccad332f9158c9a248
Autor:
Rajesh Melaram, James Adefisoye, Donald E. Warden, Stephen Potter, Hasan Arshad, Hongmei Zhang
Publikováno v:
World Allergy Organization Journal, Vol 17, Iss 10, Pp 100976- (2024)
Background: Pollen exposure is an environmental risk factor for asthma symptoms and allergic reactions in children. The extent to which pollen exposure in pregnancy and the first year of life influences the development of childhood asthma and rhiniti
Externí odkaz:
https://doaj.org/article/96074f0aaef740f195a753ea45089897
Autor:
Nirav N. Shah, Michael Wang, Lindsey E. Roeker, Krish Patel, Jennifer A. Woyach, William G. Wierda, Chaitra S. Ujjani, Toby A. Eyre, Pier Luigi Z inzani, Alvaro J. Alencar, Paolo Ghia, Nicole Lamanna, Marc S. Hoffmann, Manish R. Patel, Ian Flinn, James N. Gerson, Shuo Ma, Catherine C. Coombs, Chan Y. Cheah, Ewa Lech-Maranda, Bita Fakhri, Won Seog Kim, Minal A. Barve, Jonathon B. Cohen, Wojciech Jurczak, Talha Munir, Meghan C. Thompson, Donald E. Tsai, Katherine Bao, Nicholas A. Cangemi, Jennifer F. Kherani, Richard A. Walgren, Hongmei Han, Amy S. Ruppert, Jennifer R. Brown
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Bruton tyrosine kinase inhibitors (BTKi) have transformed the treatment of B-cell malignancies, but intolerance has often led to their discontinuation. The phase 1/2 BRUIN study evaluated pirtobrutinib, a highly selective non-covalent (reversible) BT
Externí odkaz:
https://doaj.org/article/14e14931fbe749748bffaa96d517c4bb