Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Donald D. Smyth"'
Autor:
Donald D. Smyth, Francis M. Amara
Publikováno v:
Medical Science Educator. 25:455-466
Medical schools are engaged in curricular renewal to meet the demands of training physicians in a changing healthcare environment for the twenty-first century. Therefore, there is an urgent need to reassess the breath and depth of basic sciences requ
Autor:
Grant N. Pierce, James A. Thliveris, Floribeth Aguilar, Donald D. Smyth, Clayton E. Heyliger, Asad Junaid, Tod A. Clark, Hae K. Kim, Andrea L. Edel, Michele A Merchant, Melanie A. Kopilas
Publikováno v:
Metabolism. 61:742-753
Vanadium can induce potent hypoglycemic effects in type 1 and type 2 diabetes mellitus animals, but toxic adverse effects have inhibited the translation of these findings. Administration of vanadate in a black tea decoction has shown impressive hypog
Publikováno v:
Hepatology. 35:167-175
The regulation of renal sodium and water excretion through a hepatorenal reflex activated by the changes in hemodynamics of the portal circulation has been suggested. We hypothesize that the changes in intrahepatic blood flow and flow-related intrahe
Autor:
S. Brian Penner, Donald D. Smyth
Publikováno v:
Journal of the Autonomic Nervous System. 72:155-162
The ability of imidazoline agonists, such as moxonidine and rilmenidine, to lower blood pressure has been attributed to a central effect resulting in a decrease in peripheral sympathetic nerve activity. A similar decrease in sympathetic nerve activit
Autor:
H.D. Intengan, Donald D. Smyth
Publikováno v:
British Journal of Pharmacology. 121:861-866
1. The alpha 2a/d-adrenoceptor subtype in the rat kidney modulates solute excretion (osmolar clearance). Since the kidney plays a role in chronic regulation of blood pressure, altered renal function may be implicated in the development of hypertensio
Autor:
S. Brian Penner, Donald D. Smyth
Publikováno v:
Neurochemistry International. 30:55-62
Previous studies have reported on the effects of intracerebroventricular (icv) administration of the I1-imidazoline receptor agonist moxonidine. In the present study, the relationship between increasing doses of the I1-agonist rilmenidine (administer
Autor:
S. Brian Penner, Donald D. Smyth
Publikováno v:
Annals of the New York Academy of Sciences. 763:353-356
Autor:
Henry Osborne, Francis K. Darkwa, Gordon F. Anderson, C.H. Cho, Joseph C. Dunbar, A.K. Bashir, Pablo Muriel, B.H. Alia, Patricia Bolaños González, Donald D. Smyth, Robin A. Barraco, Elaine Breslin, J.K.S. Ko, Carolyn Clough-Helfman, James Geraghty, X.G. Liu, Teresa Cawley, Jaseem Anwer, M.O.M. Tanira, Magdi R.I. Soliman, Lourdes Rodríguez-Fragoso, James R. Docherty
Publikováno v:
Pharmacology. 51:I-IV
Autor:
M.O.M. Tanira, Teresa Cawley, Pablo Muriel, Elaine Breslin, Donald D. Smyth, Gordon F. Anderson, Lourdes Rodríguez-Fragoso, Jaseem Anwer, Francis K. Darkwa, J.K.S. Ko, Magdi R.I. Soliman, James Geraghty, B.H. Alia, Joseph C. Dunbar, James R. Docherty, Henry Osborne, Robin A. Barraco, A.K. Bashir, Carolyn Clough-Helfman, X.G. Liu, Patricia Bolaños González, C.H. Cho
Publikováno v:
Pharmacology. 51:400-404
Publikováno v:
The Journal of Clinical Pharmacology. 33:1110-1115
In animal studies, acute interruption of the activity of renal alpha-1 adrenoceptors by renal denervation results in an increase in sodium and water excretion. Chronic selective blockade of alpha-1 adrenoceptors by prazosin in clinical practice has b