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Autor:
Robert M. Arduini, Mary Beth Carter, Wen-Cherng Lee, Feng Shan, Xiamei Zhang, Juswinder Singh, Jessica E. Friedman, H.-Kam Cheung, Alan Gill, Mark Cornebise, Harry Sweigard, Donald Costa, Kai Fu, Michael J. Choi, Scott Bowes, P. Ann Boriack-Sjodin, Serene Josiah, Dongyu Sun, Michael J. Corbley, Claudio Chuaqui, Miki N. Newman, Jonathan N. Mead, Lihong Sun, James L. Papadatos, Leona E. Ling, Xin Zhang, Frank Lutterodt
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:665-671
Objective— TGF-β plays a significant role in vascular injury-induced stenosis. This study evaluates the efficacy of a novel, small molecule inhibitor of ALK5/ALK4 kinase, in the rat carotid injury model of vascular fibrosis. Methods and Results—