Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Donald C. Shields"'
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2581 (2023)
Osteoporosis is a common skeletal disorder which can severely limit one’s ability to complete daily tasks due to the increased risk of bone fractures, reducing quality of life. Spinal cord injury (SCI) can also result in osteoporosis and sarcopenia
Externí odkaz:
https://doaj.org/article/cd12a93aff08471eb8c7002d90ecaca5
Autor:
Nicole C.R. McLaughlin, Darin D. Dougherty, Emad Eskandar, Herbert Ward, Kelly D. Foote, Donald A. Malone, Andre Machado, William Wong, Mark Sedrak, Wayne Goodman, Brian H. Kopell, Fuad Issa, Donald C. Shields, Osama A. Abulseoud, Kendall Lee, Mark A. Frye, Alik S. Widge, Thilo Deckersbach, Michael S. Okun, Dawn Bowers, Russell M. Bauer, Dana Mason, Cynthia S. Kubu, Ivan Bernstein, Kyle Lapidus, David L. Rosenthal, Robert L. Jenkins, Cynthia Read, Paul F. Malloy, Stephen Salloway, David R. Strong, Richard N. Jones, Steven A. Rasmussen, Benjamin D. Greenberg
Publikováno v:
Contemporary Clinical Trials Communications, Vol 22, Iss , Pp 100785- (2021)
Obsessive-compulsive disorder (OCD), a leading cause of disability, affects ~1–2% of the population, and can be distressing and disabling. About 1/3 of individuals demonstrate poor responsiveness to conventional treatments. A small proportion of th
Externí odkaz:
https://doaj.org/article/7cf60de9e0aa4ef1986809aeae845de9
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 1, p 020 (2022)
Parkinson’s disease (PD) is a progressive, neurodegenerative condition of the central nervous system (CNS) affecting 6.3 million people worldwide with no curative treatments. Current therapies aim to mitigate PD’s effects and offer symptomatic re
Externí odkaz:
https://doaj.org/article/ddfa32cf1c074a9587f9e4d22c4b81d1
Autor:
Kelsey P. Drasites, Ramsha Shams, Vandana Zaman, Denise Matzelle, Donald C. Shields, Dena P. Garner, Christopher J. Sole, Azizul Haque, Narendra L. Banik
Publikováno v:
Brain Sciences, Vol 10, Iss 12, p 933 (2020)
A spinal cord injury (SCI) may lead to loss of strength, sensation, locomotion and other body functions distal to the lesion site. Individuals with SCI also develop secondary conditions due to the lack of skeletal muscle activity. As SCI case numbers
Externí odkaz:
https://doaj.org/article/74bf4abe01134d5c9fec3a0f787b4e25
Publikováno v:
Interdisciplinary Neurosurgery, Vol 2, Iss 4, Pp 169-176 (2015)
Background: Treatment modalities for degenerative cervical spine disease are widely debated and refined as new surgical techniques are developed. The current case series compares two common cervical spine procedures, anterior cervical discectomy and
Externí odkaz:
https://doaj.org/article/2fdf354570014495b0ad28f1e2970d45
Autor:
Abhay K. Varma, Russel J. Reiter, Arabinda Das, Narendra L Banik, Azizul Haque, Donald C. Shields
Publikováno v:
Melatonin Research. 4:336-347
Recent studies suggest ex vivo modeling of neuronal injury is a robust approach for the mechanistic study of neurodegeneration. Melatonin, an indolamine, is a versatile molecule with antioxidative, antiapoptotic, neuroprotective, and anti-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64eeec38140528af4ee0fd1f9a74aeff
https://doi.org/10.32794/mr11250098
https://doi.org/10.32794/mr11250098
Autor:
Azizul Haque, Denise Matzelle, Donald C. Shields, Kelsey P. Drasites, Narendra L. Banik, Ramsha Shams, Vandana Zaman
Publikováno v:
Metab Brain Dis
Parkinson's disease (PD) is a neurodegenerative disorder etiologically linked to the loss of substantia nigra (SN) dopaminergic neurons in the mid-brain. The etiopathology of sporadic PD is still unclear; however, the interaction of extrinsic and int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233dd3abb6de18faf335991c78a45006
https://doi.org/10.1007/s11011-021-00689-5
https://doi.org/10.1007/s11011-021-00689-5
Autor:
Naren L. Banik, Mollie Capone, Denise Matzelle, Abhay K. Varma, Azizul Haque, Alexey Vertegel, Donald C. Shields, April Cox, Mikhail Bredikhin
Publikováno v:
Journal of Neurotrauma. 38:342-352
Spinal cord injury (SCI) patients sustain significant functional impairments; this is causally related to restricted neuronal regeneration after injury. The ensuing reactive gliosis, inflammatory cascade, and glial scar formation impede axonal regrow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e873f2a7fa095c57301bd9e096f7ea
https://doi.org/10.1089/neu.2020.7047
https://doi.org/10.1089/neu.2020.7047
Publikováno v:
J Cereb Blood Flow Metab
Although relatively few in number compared to astrocytes and neurons, microglia demonstrate multiple, varied neuroimmunological functions in the central nervous system during normal and pathological states. After injury to the brain or spinal cord, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e03766f106042554d69b8637d29d97
https://doi.org/10.1177/0271678x20965786
https://doi.org/10.1177/0271678x20965786
Autor:
Jun Inoue, John J. Woodward, Supriti Samantaray, Naren L. Banik, Mitsuyoshi Azuma, Varduhi H. Knaryan, Angelo M. Del Re, Donald C. Shields, Swapan K. Ray
Publikováno v:
Neurotox Res
Extra-nigral central nervous system sites have been found to be affected in Parkinson’s disease (PD). In addition to substantia nigra, degeneration of spinal cord motor neurons may play a role in the motor symptoms of PD. To this end, hybrid rodent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a28ee9c97a3486c8e1ca2eeaaaecbb0
https://doi.org/10.1007/s12640-020-00264-3
https://doi.org/10.1007/s12640-020-00264-3