Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Donald C Sheppard"'
Autor:
Quynh T Phan, Norma V Solis, Jianfeng Lin, Marc Swidergall, Shakti Singh, Hong Liu, Donald C Sheppard, Ashraf S Ibrahim, Aaron P Mitchell, Scott G Filler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010681 (2022)
During hematogenously disseminated candidiasis, blood borne fungi must invade the endothelial cells that line the blood vessels to infect the deep tissues. Although Candida albicans, which forms hyphae, readily invades endothelial cells, other medica
Externí odkaz:
https://doaj.org/article/743b5ca3cf9542828ee062ad7674967c
Autor:
Brendan D Snarr, Guillaume St-Pierre, Benjamin Ralph, Mélanie Lehoux, Yukiko Sato, Ann Rancourt, Takahiro Takazono, Shane R Baistrocchi, Rachel Corsini, Matthew P Cheng, Michele Sugrue, Lindsey R Baden, Koichi Izumikawa, Hiroshi Mukae, John R Wingard, Irah L King, Maziar Divangahi, Masahiko S Satoh, Bryan G Yipp, Sachiko Sato, Donald C Sheppard
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008741 (2020)
Aspergillus fumigatus is an opportunistic mold that infects patients who are immunocompromised or have chronic lung disease, causing significant morbidity and mortality in these populations. While the factors governing the host response to A. fumigat
Externí odkaz:
https://doaj.org/article/414657841db046fa861b75d2c1b81a56
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007411 (2018)
Externí odkaz:
https://doaj.org/article/61cda074886e4b6fb21e35a1b14f9b25
Autor:
Dustin J Little, Roland Pfoh, François Le Mauff, Natalie C Bamford, Christina Notte, Perrin Baker, Manita Guragain, Howard Robinson, Gerald B Pier, Mark Nitz, Rajendar Deora, Donald C Sheppard, P Lynne Howell
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006998 (2018)
Poly-β(1,6)-N-acetyl-D-glucosamine (PNAG) is a major biofilm component of many pathogenic bacteria. The production, modification, and export of PNAG in Escherichia coli and Bordetella species require the protein products encoded by the pgaABCD opero
Externí odkaz:
https://doaj.org/article/eb91361e84b14e24a860218a28db4e5a
Autor:
Mark J Lee, Hong Liu, Bridget M Barker, Brendan D Snarr, Fabrice N Gravelat, Qusai Al Abdallah, Christina Gavino, Shane R Baistrocchi, Hanna Ostapska, Tianli Xiao, Benjamin Ralph, Norma V Solis, Mélanie Lehoux, Stefanie D Baptista, Arsa Thammahong, Robert P Cerone, Susan G W Kaminskyj, Marie-Christine Guiot, Jean-Paul Latgé, Thierry Fontaine, Donald C Vinh, Scott G Filler, Donald C Sheppard
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005187 (2015)
Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and N-acetyl-galactosamine (GalNAc) that med
Externí odkaz:
https://doaj.org/article/b6d5e976b224466ca13478d65ff74e9e
Autor:
Fabrice N Gravelat, Anne Beauvais, Hong Liu, Mark J Lee, Brendan D Snarr, Dan Chen, Wenjie Xu, Ilia Kravtsov, Christopher M Q Hoareau, Ghyslaine Vanier, Mirjam Urb, Paolo Campoli, Qusai Al Abdallah, Melanie Lehoux, Josée C Chabot, Marie-Claude Ouimet, Stefanie D Baptista, Jörg H Fritz, William C Nierman, Jean Paul Latgé, Aaron P Mitchell, Scott G Filler, Thierry Fontaine, Donald C Sheppard
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003575 (2013)
Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The mechanisms underlying the adherence of this mold to host cells and macromolecules have remained elusive. Using mutants with different adhesive properties and compa
Externí odkaz:
https://doaj.org/article/d06a822e71b545c58886aa7785638637
Autor:
Jenny-Lee Thomassin, Mark J Lee, John R Brannon, Donald C Sheppard, Samantha Gruenheid, Hervé Le Moual
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82475 (2013)
Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) are food-borne pathogens that colonize the small intestine and colon, respectively. To cause disease, these pathogens must overcome the action of different host antimicrobial pep
Externí odkaz:
https://doaj.org/article/45d9db1887254ff8905678f9b6f40112
Autor:
Mirjam Urb, Donald C Sheppard
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002619 (2012)
Externí odkaz:
https://doaj.org/article/c68f0d0f21204d17949b1b1599624793
Autor:
Qusai Al Abdallah, Se-In Choe, Paolo Campoli, Stefanie Baptista, Fabrice N Gravelat, Mark J Lee, Donald C Sheppard
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49959 (2012)
MedA is a developmental regulator that is conserved in the genome of most filamentous fungi. In the pathogenic fungus Aspergillus fumigatus MedA regulates conidiogenesis, adherence to host cells, and pathogenicity. The mechanism by which MedA governs
Externí odkaz:
https://doaj.org/article/64e7d39632734643b83eb0e639a0150e
Autor:
Quynh T Phan, Carter L Myers, Yue Fu, Donald C Sheppard, Michael R Yeaman, William H Welch, Ashraf S Ibrahim, John E Edwards, Scott G Filler
Publikováno v:
PLoS Biology, Vol 5, Iss 3, p e64 (2007)
Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C. albicans hyphae invade endothelial ce
Externí odkaz:
https://doaj.org/article/7de12b1cc3b141c5b28ce0aacaecaed3