Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Donald Buchsbaum"'
2
Manipulating the epigenetic framework of T cells with histone deacetylase inhibitors for more robust and durable anti-tumor responses
Autor: Tyler R. McCaw, Mingyong Liu, Mei Li, Dmytro Starenki, Sara Cooper, Rebecca Arend, Andres Forero, Donald Buchsbaum, Troy Randall
Publikováno v: The Journal of Immunology. 200:57.41-57.41
Malignant cells often harbor an imbalance in histone acetyltransferase and histone deacetylase (HDAC) activity, which can be disrupted by HDAC inhibitors. We hypothesized that HDAC inhibition can boost anti-tumor T cell responses by modifying tumor c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8eba303ba2e420347c2291c0a544ec24
https://doi.org/10.4049/jimmunol.200.supp.57.41
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3
Induced MHCII expression on breast cancer cells broadens the responding T cell repertoire, delays tumor-specific T cell exhaustion, and impairs tumor growth
Autor: Tyler R McCaw, Mei Li, Dmytro Starenki, Sara Cooper, Selene Meza-Perez, Donald Buchsbaum, Andres Forero, Troy D. Randall
Publikováno v: The Journal of Immunology. 198:204.26-204.26
We recently reported that aberrant expression of Major Histocompatibility Class II (MHCII) on human triple negative breast cancer cells correlates with increased tumor infiltrating lymphocytes and prolonged progression free survival. This observation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::254c8aebff424c3918840142ceb9070d
https://doi.org/10.4049/jimmunol.198.supp.204.26
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5
Experimental radioimmunotherapy
Autor: Donald Buchsbaum
Publikováno v: Seminars in radiation oncology. 10(2)
Experimental radioimmunotherapy (RIT) studies in animal models have contributed significantly to the design of clinical RIT protocols, although the results have not always been directly translated. Reviewed in this article are current areas of active
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdada8833a2e02bc9a3ab22119fd638c
https://pubmed.ncbi.nlm.nih.gov/10727604
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6
Antigenic modulation by anti-CD5 immunotoxins
Autor: Manske, J. M., Donald Buchsbaum, Azemove, S. M., Hanna, D. E., Vallera, D. A.
Publikováno v: Scopus-Elsevier
We evaluated the modulation of T101 immunotoxins (IT) and free T101 antibody from the surface of normal and leukemic cells to determine whether the presence of toxin on antibody affected antigenic modulation. Reagents were made by conjugating T101, w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504876de74b326d337c01666fa9005ea
https://doi.org/10.4049/jimmunol.136.12.4721
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8
The role of ricin B chain in the intracellular trafficking of anti-CD5 immunotoxins
Autor: Manske, J. M., Donald Buchsbaum, Vallera, D. A.
Publikováno v: Scopus-Elsevier
The mAb anti-CD5 was linked to purified ricin A chain (RTA) or intact ricin (Rc) containing B chain to determine the role of ricin B chain in the intracellular trafficking of anti-CD5 immunotoxins (IT). IT were radiolabeled with iodine-125 and then s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46c52c15ef48f7418c5723a1f0d874b
http://www.scopus.com/inward/record.url?eid=2-s2.0-0024565152&partnerID=MN8TOARS
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