Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Donald Bierer"'
Autor:
Qiupeng Peng, Bingjia Yan, Fangyi Li, Ming Lang, Bei Zhang, Donghui Guo, Donald Bierer, Jian Wang
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-7 (2021)
Organocatalysed 1,3-proton shifts can offer efficient access to chiral nonracemic fluorinated products. Here chiral amino amides are obtained in high enantiomeric ratio via enantioselective 1,3- proton shift of β,β-difluoro-αimino amides.
Externí odkaz:
https://doaj.org/article/1de551ea3e41486491b5d7bb4b7f4168
Publikováno v:
Molecules, Vol 26, Iss 6, p 1790 (2021)
DNA-encoded libraries (DEL) are increasingly being used to identify new starting points for medicinal chemistry in drug discovery. Herein, we discuss the development of methods that allow the conversion of both primary amines and anilines, attached t
Externí odkaz:
https://doaj.org/article/6adef572abf9432084b35d904d3f6eb2
Publikováno v:
New Journal of Chemistry. 47:4213-4217
We report a new diaminodiacid containing an ethylene glycol bridge for the synthesis of disulfide surrogate peptides.
Autor:
Alexandros Vakalopoulos, Frank Wunder, Ingo V. Hartung, Gorden Redlich, Rolf Jautelat, Philipp Buchgraber, Jorma Hassfeld, Alexey V. Gromov, Niels Lindner, Donald Bierer, Jörg Gries, Walter Kroh, Holger Paulsen, Joachim Mittendorf, Dieter Lang, Eva Becker-Pelster, Damian Brockschnieder, Volker Geiss, Volkhart Li, Alexander Straub, Andreas Knorr, Thomas Mondritzki, Hubert Trübel, Marian Raschke, Martina Schaefer, Dirk Thomas, Peter Sandner, Johannes-Peter Stasch, Markus Follmann
Publikováno v:
Journal of Medicinal Chemistry.
Autor:
Wei-Wei Shi, Chaowei Shi, Tong-Yue Wang, Yu-Lei Li, Yong-Kang Zhou, Xu-Han Zhang, Donald Bierer, Ji-Shen Zheng, Lei Liu
Publikováno v:
Journal of the American Chemical Society. 144:349-357
Autor:
Rui Zhao, Pan Shi, Ji‐bin Cui, Chaowei Shi, Xiao‐Xiong Wei, Jie Luo, Zhemin Xia, Wei‐Wei Shi, Yingxin Zhou, Jiahui Tang, Changlin Tian, Mark Meininghaus, Donald Bierer, Jing Shi, Yi‐Ming Li, Lei Liu
Publikováno v:
Angewandte Chemie. 135
Chemical synthesis of insulin superfamily proteins (ISPs) has recently been widely studied to develop next-generation drugs. Separate synthesis of multiple peptide fragments and tedious chain-to-chain folding are usually encountered in these studies,
Autor:
Kevin Kretschmer, Jan Stichel, Kathrin Bellmann‐Sickert, Lars Baumann, Donald Bierer, Bernd Riedl, Annette G. Beck‐Sickinger
Publikováno v:
Journal of Peptide Science. 29
Semaphorin-3A (Sema-3A) is a chemorepellant protein with various biological functions, including kidney development. It interacts with a protein complex consisting of the receptors neuropilin-1 (NRP-1) and plexin-A1. After acute kidney injury, Sema-3
Autor:
Anke Schink, Anu Bheemaiah Machettira, Elisabeth Asmus, Neil R. Judge, Donald Bierer, Géraud Chacktas, Rainer Buckpesch, Hansjörg Dietrich, Ling Ma, Dirk Schmutzler, Michael Charles Mcleod
Publikováno v:
European Journal of Organic Chemistry. 2021:5677-5684
Autor:
Yanyan Guo, Junyou Chen, Rui Zhao, Yi-Ming Li, Jiahui Tang, Donald Bierer, Tingting Cui, Yulei Li, Lei Liu
Publikováno v:
Chinese Journal of Chemistry. 39:2517-2522
Autor:
Yanyan Guo, Jun Wang, Donald Bierer, Shuaishuai Sun, Yi-Ming Li, Jingnan Chen, Tingting Cui, Junyou Chen
Publikováno v:
The Journal of Organic Chemistry. 86:8610-8619
Lactam cyclic peptides are a class of interesting and pharmaceutically active molecules, but their previous syntheses have required the use of heavy metals and/or forcing conditions. Here, we describe the efficient application of the previously repor