Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Donald Bankston"'
Autor:
Ruoxi Lan, Hui Tian, Dusica Santos, Lizbeth Celeste Deselm, Jing Lin, Donald Bankston, Constantin Neagu, Sherer Brian A, Jennifer Jackson, Jared Head, Jianguo Ma, Xuliang Jiang, Sakeena Syed, Anderson Clark, Andreas Machl, Yufang Xiao, Erik Wilker, Anna Gardberg, Xiaoling Chen, Igor Mochalkin, Bayard R. Huck, Hui Qiu, Christopher Charles Victor Jones, Vikram Dutt, Johnson Theresa L, Andreas Goutopoulos
Publikováno v:
Bioorganicmedicinal chemistry letters. 50
Activation of the PI3K/Akt/mTOR kinase pathway is associated with human cancers. A dual p70S6K/Akt inhibitor is sufficient to inhibit strong tumor growth and to block negative impact of the compensatory Akt feedback loop activation. A scaffold dockin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c34ccf70712c4f9a6c835cbbed5b0bb
https://pubmed.ncbi.nlm.nih.gov/35484006
https://pubmed.ncbi.nlm.nih.gov/35484006
Autor:
Yufang Xiao, Bayard R. Huck, Ruoxi Lan, Lizbeth DeSelm, Xiaoling Chen, Hui Qiu, Constantin Neagu, Theresa Johnson, Igor Mochalkin, Anna Gardberg, Xuliang Jiang, Hui Tian, Vikram Dutt, Dusica Santos, Jared Head, Jennifer Jackson, Sakeena Syed, Jing Lin, Erik Wilker, Jianguo Ma, Anderson Clark, Andreas Machl, Donald Bankston, Christopher C.V. Jones, Andreas Goutopoulos, Brian Sherer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 67:128758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e61734db4df8304c34df6aa92d38de6
https://doi.org/10.1016/j.bmcl.2022.128758
https://doi.org/10.1016/j.bmcl.2022.128758
Autor:
Barbara Hibner, Nancy Kennure, Bernd Riedl, Donald John Wolanin, Wendy Lee, Xiao-Gao Liu, Reina Natero, Donald Bankston, Hong Rong, Uday Khire, Todd Gane, Roger A. Smith, Robert O. Carlson, Jacques Dumas, Ian McAlexander, Jill Kingery-Wood, Sarah Heald, Timothy B. Lowinger, Jeffrey Johnson, Robert Sibley, James Barbosa, Joel Renick, Michael E Katz, Yolanda V Caringal, David R. Brittelli, Mary-Katherine Monahan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:783-786
Bis-aryl ureas have been disclosed previously as a potent class of Raf kinase inhibitors. Modifications in the amide portion led to an improvement in aqueous solubility, an important characteristic for an oral drug. Based on this finding, we hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93687468b54d65b2e0109513b7ee5eb5
https://doi.org/10.1016/j.bmcl.2003.11.041
https://doi.org/10.1016/j.bmcl.2003.11.041
Autor:
Mary-Katherine Monahan, Robert Sibley, Jacques Dumas, Reina Natero, Donald Bankston, Bernd Riedl
Publikováno v:
Organic Process Research & Development. 6:777-781
Urea 3 (BAY 43-9006), a potent Raf kinase inhibitor, was prepared in four steps with an overall yield of 63%. Significant process research enabled isolation of each intermediate and target without chromatographic purification, and overall yield incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fb964f8c2274e5d0f2677b9f43cdef0
https://doi.org/10.1021/op020205n
https://doi.org/10.1021/op020205n
Autor:
Donald Bankston
Publikováno v:
ChemInform. 35
Aqueous dimethylamine is an efficient reagent for the conversion of a variety of benzal halides to their corresponding benzaldehydes. Studies indicate that aqueous dimethylamine significantly accelerates aldehyde formation from benzal halide precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd86631c207ff9aecabfdefc3d0b5ff
https://doi.org/10.1002/chin.200423096
https://doi.org/10.1002/chin.200423096
Autor:
Uday R, Khire, Donald, Bankston, James, Barbosa, David R, Brittelli, Yolanda, Caringal, Robert, Carlson, Jacques, Dumas, Todd, Gane, Sarah L, Heald, Barbara, Hibner, Jeffrey S, Johnson, Michael E, Katz, Nancy, Kennure, Jill, Kingery-Wood, Wendy, Lee, Xiao-Gao, Liu, Timothy B, Lowinger, Ian, McAlexander, Mary-Katherine, Monahan, Reina, Natero, Joel, Renick, Bernd, Riedl, Hong, Rong, Robert N, Sibley, Roger A, Smith, Donald, Wolanin
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(3)
Bis-aryl ureas have been disclosed previously as a potent class of Raf kinase inhibitors. Modifications in the amide portion led to an improvement in aqueous solubility, an important characteristic for an oral drug. Based on this finding, we hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79292863887c92f448aa8823dbad5d77
https://pubmed.ncbi.nlm.nih.gov/14741289
https://pubmed.ncbi.nlm.nih.gov/14741289
Autor:
Donald Bankston
Publikováno v:
Organic Syntheses
Oxidative cleavage of an aromatic ring: cis,cis-monomethyl muconate from 1,2-dihydroxybenzene solvent: 400 mL of pyridine product: cis,cis-monomethyl muconate Keywords: oxidation, CC 2 CO2H; ring opening reactions; pyridine; benzene; apparatus, for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad215e95bcc19c2cf98a7402090ade8b
https://doi.org/10.1002/0471264180.os066.23
https://doi.org/10.1002/0471264180.os066.23
